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Clin Immunol ; 142(2): 176-93, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22154868

RESUMO

Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children and adolescents. Immunomodulatory drugs are used frequently in its treatment. Using the nominal group technique (NGT) and Delphi method, we created a multidisciplinary, evidence- and consensus-based treatment guideline for JIA based on a systematic literature analysis and three consensus conferences. Conferences were headed by a professional moderator and were attended by representatives who had been nominated by their scientific societies or organizations. 15 statements regarding drug therapy, symptomatic and surgical management were generated. It is recommended that initially JIA is treated with NSAID followed by local glucocorticoids and/or methotrexate if unresponsive. Complementing literature evidence with long-standing experience of caregivers allows creating guidelines that may potentially improve the quality of care for children and adolescents with JIA.


Assuntos
Anti-Inflamatórios não Esteroides/uso terapêutico , Anticorpos Monoclonais/uso terapêutico , Artrite Juvenil/terapia , Conferências de Consenso como Assunto , Metotrexato/uso terapêutico , Adolescente , Criança , Pré-Escolar , Terapia Combinada , Medicina Baseada em Evidências , Glucocorticoides/uso terapêutico , Humanos , Guias de Prática Clínica como Assunto , Adulto Jovem
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