Detalhe da pesquisa
1.
Can Nitric Oxide-Based Therapy Be Improved for the Treatment of Cancers? A Perspective.
Int J Mol Sci
; 24(17)2023 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37686417
2.
Molecular Mechanisms of Cytotoxicity of NCX4040, the Non-Steroidal Anti-Inflammatory NO-Donor, in Human Ovarian Cancer Cells.
Int J Mol Sci
; 23(15)2022 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35955744
3.
Nitric oxide inhibits topoisomerase II activity and induces resistance to topoisomerase II-poisons in human tumor cells.
Biochim Biophys Acta
; 1860(7): 1519-27, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27095671
4.
DNA cleavage and detection of DNA radicals formed from hydralazine and copper (II) by ESR and immuno-spin trapping.
Chem Res Toxicol
; 27(4): 674-82, 2014 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24502259
5.
A Role for iNOS in Erastin Mediated Reduction of P-Glycoprotein Transport Activity.
Cancers (Basel)
; 16(9)2024 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38730685
6.
Effect of nitric oxide on the anticancer activity of the topoisomerase-active drugs etoposide and adriamycin in human melanoma cells.
J Pharmacol Exp Ther
; 347(3): 607-14, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24049059
7.
Role of nitric oxide in the chemistry and anticancer activity of etoposide (VP-16,213).
Chem Res Toxicol
; 26(3): 379-87, 2013 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23402364
8.
Ferroptosis-Mediated Cell Death Induced by NCX4040, The Non-Steroidal Nitric Oxide Donor, in Human Colorectal Cancer Cells: Implications in Therapy.
Cells
; 12(12)2023 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37371096
9.
Gene Expression Profiling Elucidates Cellular Responses to NCX4040 in Human Ovarian Tumor Cells: Implications in the Mechanisms of Action of NCX4040.
Cancers (Basel)
; 15(1)2022 Dec 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36612280
10.
NCX-4040, a Unique Nitric Oxide Donor, Induces Reversal of Drug-Resistance in Both ABCB1- and ABCG2-Expressing Multidrug Human Cancer Cells.
Cancers (Basel)
; 13(7)2021 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33918289
11.
Elucidation of Mechanisms of Topotecan-Induced Cell Death in Human Breast MCF-7 Cancer Cells by Gene Expression Analysis.
Front Genet
; 11: 775, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32765594
12.
Reversal of drug resistance by JS-K and nitric oxide in ABCB1- and ABCG2-expressing multi-drug resistant human tumor cells.
Biomed Pharmacother
; 120: 109468, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31605952
13.
Nitric oxide reverses drug resistance by inhibiting ATPase activity of p-glycoprotein in human multi-drug resistant cancer cells.
Biochim Biophys Acta Gen Subj
; 1862(12): 2806-2814, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30251669
14.
Nitric oxide inhibits ATPase activity and induces resistance to topoisomerase II-poisons in human MCF-7 breast tumor cells.
Biochem Biophys Rep
; 10: 252-259, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28955753
15.
Synergistic enhancement of topotecan-induced cell death by ascorbic acid in human breast MCF-7 tumor cells.
Free Radic Biol Med
; 113: 406-412, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29079526
16.
Nitric oxide: Friend or Foe in Cancer Chemotherapy and Drug Resistance: A Perspective.
J Cancer Sci Ther
; 8: 244-251, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-31844487
17.
IS METABOLIC ACTIVATION OF TOPOISOMERASE II POISONS IMPORTANT IN THE MECHANISM OF CYTOTOXICITY?
J Drug Metab Toxicol
; 6(3)2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-31171989
18.
Nitric Oxide Down-Regulates Topoisomerase I and Induces Camptothecin Resistance in Human Breast MCF-7 Tumor Cells.
PLoS One
; 10(11): e0141897, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26540186
19.
BIOTRANSFORMATION OF HYDRAZINE DERVATIVES IN THE MECHANISM OF TOXICITY.
J Drug Metab Toxicol
; 5(3)2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-31171988