Detalhe da pesquisa
1.
Parkin ubiquitination of Kindlin-2 enables mitochondria-associated metastasis suppression.
J Biol Chem
; 299(6): 104774, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37142218
2.
Interaction between TBP and Condensin Drives the Organization and Faithful Segregation of Mitotic Chromosomes.
Mol Cell
; 59(5): 755-67, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26257282
3.
A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity.
PLoS Biol
; 17(4): e3000204, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30951520
4.
Functional Interactions of Kluyveromyces lactis Telomerase Reverse Transcriptase with the Three-Way Junction and the Template Domains of Telomerase RNA.
Int J Mol Sci
; 23(18)2022 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36142669
5.
Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes.
Nucleic Acids Res
; 46(2): 972-984, 2018 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29228254
6.
Structural Analysis Reveals the Deleterious Effects of Telomerase Mutations in Bone Marrow Failure Syndromes.
J Biol Chem
; 292(11): 4593-4601, 2017 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28154186
7.
Single cell analysis of RNA-mediated histone H3.3 recruitment to a cytomegalovirus promoter-regulated transcription site.
J Biol Chem
; 288(27): 19882-99, 2013 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23689370
8.
Structure of the Tribolium castaneum telomerase catalytic subunit TERT.
Nature
; 455(7213): 633-7, 2008 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18758444
9.
Separation of telomere protection from length regulation by two different point mutations at amino acid 492 of RTEL1.
bioRxiv
; 2024 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38464183
10.
A cyclin D1 intrinsically disordered domain accesses modified histone motifs to govern gene transcription.
Oncogenesis
; 13(1): 4, 2024 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38191593
11.
Telomouse-a mouse model with human-length telomeres generated by a single amino acid change in RTEL1.
Nat Commun
; 14(1): 6708, 2023 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37872177
12.
Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation.
Hum Mol Genet
; 19(6): 1033-47, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20028791
13.
Asf1-like structure of the conserved Yaf9 YEATS domain and role in H2A.Z deposition and acetylation.
Proc Natl Acad Sci U S A
; 106(51): 21573-8, 2009 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19966225
14.
POT1-TPP1 binding stabilizes POT1, promoting efficient telomere maintenance.
Comput Struct Biotechnol J
; 20: 675-684, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35140887
15.
Telomere dysfunction implicates POT1 in patients with idiopathic pulmonary fibrosis.
J Exp Med
; 219(5)2022 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35420632
16.
Pol α-primase dependent nuclear localization of the mammalian CST complex.
Commun Biol
; 4(1): 349, 2021 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33731801
17.
Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth.
Cancer Res
; 81(5): 1252-1264, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33414169
18.
POT1-TPP1 telomere length regulation and disease.
Comput Struct Biotechnol J
; 18: 1939-1946, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32774788
19.
Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function.
Nat Commun
; 11(1): 2219, 2020 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32376827
20.
Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation.
Cell Rep
; 32(11): 108151, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32937140