Detalhe da pesquisa
1.
Using [2H]water to quantify the contribution of de novo palmitate synthesis in plasma: enabling back-to-back studies.
Am J Physiol Endocrinol Metab
; 315(1): E63-E71, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29351479
2.
Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor.
J Pharmacol Exp Ther
; 361(2): 229-244, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193636
3.
Quantifying rates of glucose production in vivo following an intraperitoneal tracer bolus.
Am J Physiol Endocrinol Metab
; 311(6): E911-E921, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27651111
4.
Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers.
Mol Syst Biol
; 8: 594, 2012 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22806142
5.
Genetic and pharmacological evaluation of cathepsin s in a mouse model of asthma.
Am J Respir Cell Mol Biol
; 45(1): 81-7, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20855652
6.
Pharmacological characterization of MK-7246, a potent and selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells) antagonist.
Mol Pharmacol
; 79(1): 69-76, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20943773
7.
ANKRD13C acts as a molecular chaperone for G protein-coupled receptors.
J Biol Chem
; 285(52): 40838-51, 2010 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20959461
8.
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases.
Bioorg Med Chem Lett
; 21(1): 288-93, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21106375
9.
A robust protocol for regional evaluation of methacholine challenge in mouse models of allergic asthma using hyperpolarized (3)He MRI.
NMR Biomed
; 28(9): 1185, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26174861
10.
A robust protocol for regional evaluation of methacholine challenge in mouse models of allergic asthma using hyperpolarized 3He MRI.
NMR Biomed
; 22(5): 502-15, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19204996
11.
Discovery of potent and selective DP1 receptor antagonists in the azaindole series.
Bioorg Med Chem Lett
; 19(8): 2125-8, 2009 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19307115
12.
Adenovirus IL-13-induced airway disease in mice: a corticosteroid-resistant model of severe asthma.
Am J Respir Cell Mol Biol
; 39(1): 26-35, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18258919
13.
Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524).
J Med Chem
; 50(4): 794-806, 2007 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17300164
14.
Differential regulation of the signaling and trafficking of the two prostaglandin D2 receptors, prostanoid DP receptor and CRTH2.
Eur J Pharmacol
; 557(2-3): 115-23, 2007 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17207480
15.
Effects of corticosteroid treatment on airway inflammation, mechanics, and hyperpolarized ³He magnetic resonance imaging in an allergic mouse model.
J Appl Physiol (1985)
; 112(9): 1437-44, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22241062
16.
Structure-function relationships in the neuropeptide S receptor: molecular consequences of the asthma-associated mutation N107I.
J Biol Chem
; 281(34): 24704-12, 2006 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-16790440
17.
Comparison between two classes of selective EP(3) antagonists and their biological activities.
Bioorg Med Chem Lett
; 16(21): 5639-42, 2006 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16931013
18.
Identification of an indole series of prostaglandin D2 receptor antagonists.
Bioorg Med Chem Lett
; 16(11): 3043-8, 2006 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16529930
19.
Gob-5 is not essential for mucus overproduction in preclinical murine models of allergic asthma.
Am J Respir Cell Mol Biol
; 33(3): 303-14, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15947424
20.
Structure-activity relationship studies on ortho-substituted cinnamic acids, a new class of selective EP(3) antagonists.
Bioorg Med Chem Lett
; 15(3): 527-30, 2005 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15664806