Detalhe da pesquisa
1.
Long-term effect of Toll-like receptor-2, -4, -5, -7 and NOD2 stimulation on Na+,K+-ATPase activity and expression in intestinal epithelial cells.
Am J Physiol Cell Physiol
; 324(5): C1028-C1038, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36847442
2.
Effect of Toll-like receptor-2, -4, -5, -7, and NOD2 stimulation on potassium channel conductance in intestinal epithelial cells.
Am J Physiol Gastrointest Liver Physiol
; 323(5): G410-G419, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36040119
3.
Inactivation Mechanism of the Fatty Acid Amide Hydrolase Inhibitor BIA 10-2474.
Chembiochem
; 23(20): e202200166, 2022 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35843872
4.
Effect of Opicapone on Levodopa Pharmacokinetics in Patients with Fluctuating Parkinson's Disease.
Mov Disord
; 37(11): 2272-2283, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36054562
5.
Absorption, metabolism and excretion of opicapone in human healthy volunteers.
Br J Clin Pharmacol
; 88(10): 4540-4551, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35508762
6.
Opicapone versus placebo in the treatment of Parkinson's disease patients with end-of-dose motor fluctuation-associated pain: rationale and design of the randomised, double-blind OCEAN (OpiCapone Effect on motor fluctuations and pAiN) trial.
BMC Neurol
; 22(1): 88, 2022 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35279112
7.
Opicapone Use in Clinical Practice across Germany: A Sub-Analysis of the OPTIPARK Study in Parkinson's Disease Patients with Motor Fluctuations.
Eur Neurol
; 85(5): 389-397, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35350024
8.
Non-clinical toxicology evaluation of BIA 10-2474.
Crit Rev Toxicol
; 51(1): 65-75, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33528291
9.
Complex effects of eslicarbazepine on inhibitory micro networks in chronic experimental epilepsy.
Epilepsia
; 62(2): 542-556, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33452820
10.
Antagonistic modulation of SIK1 and SIK2 isoforms in high blood pressure and cardiac hypertrophy triggered by high-salt intake.
Clin Exp Hypertens
; 43(5): 428-435, 2021 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33688765
11.
Long-term efficacy and safety of eslicarbazepine acetate monotherapy for adults with newly diagnosed focal epilepsy: An open-label extension study.
Epilepsia
; 61(10): 2129-2141, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32944934
12.
Analysis of cutaneous allergic reactions in clinical trials of eslicarbazepine acetate.
Acta Neurol Scand
; 141(5): 397-404, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-31894578
13.
Efficacy and safety of eslicarbazepine acetate as adjunctive therapy for refractory focal-onset seizures in children: A double-blind, randomized, placebo-controlled, parallel-group, multicenter, phase-III clinical trial.
Epilepsy Behav
; 105: 106962, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32151803
14.
Effects of nepicastat upon dopamine-ß-hydroxylase activity and dopamine and norepinephrine levels in the rat left ventricle, kidney, and adrenal gland.
Clin Exp Hypertens
; 42(2): 118-125, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-30821508
15.
Polyamine Modulation of Anticonvulsant Drug Response: A Potential Mechanism Contributing to Pharmacoresistance in Chronic Epilepsy.
J Neurosci
; 38(24): 5596-5605, 2018 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29789377
16.
Bioelectrical impedance analysis of body composition for the anesthetic induction dose of propofol in older patients.
BMC Anesthesiol
; 19(1): 180, 2019 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31604419
17.
Effects of eslicarbazepine on slow inactivation processes of sodium channels in dentate gyrus granule cells.
Epilepsia
; 59(8): 1492-1506, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29953587
18.
Efficacy and safety of eslicarbazepine acetate versus controlled-release carbamazepine monotherapy in newly diagnosed epilepsy: A phase III double-blind, randomized, parallel-group, multicenter study.
Epilepsia
; 59(2): 479-491, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29369348
19.
Elucidation of the Impact of P-glycoprotein and Breast Cancer Resistance Protein on the Brain Distribution of Catechol-O-Methyltransferase Inhibitors.
Drug Metab Dispos
; 45(12): 1282-1291, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28916530
20.
Pharmacokinetics of opicapone, a third-generation COMT inhibitor, after single and multiple oral administration: A comparative study in the rat.
Toxicol Appl Pharmacol
; 323: 9-15, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28322896