[Syndrome of catecholamine hypersecretion secondary to a jejuno-ileal bypass]. / Sindrome da iperincrezione catecolaminica secondaria a by-pass digiuno-ileale.

Hypersecretion of catecholamine primarily affecting adrenaline levels arose in a patient given a jejunoileal bypass for severe obesity. Apart from organic factors, including a hetero and/or orthotopic pheochromocytoma and the therapeutic effect of beta-blocking drugs, it is suggested that the pathogenesis of the patient's condition is based on a hypersecretion of VIP, as sometimes occurs in patients with short intestine/syndrome.

[Changes in some plasma parameters in the course of dextran 40]. / Sulle modificazioni di talune varianti plasmatiche in corso di terapia perfusionale con Dextran 40

Changes in certainplasma parameters (Hc, arterial and venous VP, creatinine clearance, potassium, PA and FC) induced by Dextran 40 perfusions (500 ml at 40 drops/min and 250 ml at 20 drops/min) were examined in 50 patients. The expander effect was more intense, though less protracted when the larger quantity was used. A rebound effect 24 hr after the test was also more frequent percentage-wise in this group. Significant changes in Hc were not observed for 24 hr and 96 hr respectively with the higher and the lower dose. The venous district was primarily concerned. There were also increases in blood potassium, FC and max PA, while min PA and blood proteins fell. No relation could be demonstrated between creatinine clearance and diuresis at the end of the test with respect to the amount of Dextran employed. None of these latter modifications was significant. There were no signs of intolerance.

[Relations between athero-arteriosclerosis and chronic liver diseases. Anatomopathological and statistical studies]. / Sui rapporti tra atero-arteriosclerosi ed epatopatie croniche. Indagine anatomopatologica e statistica.

Starting from well known anatomopathological premises and on the basis of relative physiopathological concepts, particularly lipid metabolism and the lipidaemic fractions in patients suffering from chronic hepatopathy and athero-arteriosclerosis, a statistical investigation was carried out into the relations between the two disease conditions on the basis of the anatomopathological material collected over a period of six years in the S. Giovanni and S. Giacomo Hospitals in Rome. The conclusion is that there is a smaller incidence of athero-arteriosclerotic pathology in patients suffering from chronic hepatopathy up to the sixth decade of life.

[Clinical and aetiopathogenetic notes on 6 cases of acute amentia in patients with gangrene due to obstruction of the lower extremity arteries]. / La sindrome amenziale acuta nelle gangrene da arteriopatia ostruttiva degli arti inferiori (considerazioni cliniche ed etiopatogenetiche).

Six cases of acute amentia in a series of 58 subjects with lower extremity artery obstruction are described and their possible pathogenesis is discussed in the light of present biological, physiopathological and psychopharmacological views. Radical surgery brings resolution of amentia syndromes of this type and its desirability in such cases is stressed.

[Changes of plasma renin activity during perfusion with dextran 40. Functional study; statistical evaluations and cl-nical considerations]. / Variazioni della attività plasmatica reninica in corso di perfusione con dextran "40". Studio funzionale; valutazioni statistiche e considerazioni cliniche.

Changes in RAP, AP (max and min), Ht and R.R. induced by daily perfusion with 250 and 500 ml Dextran 40 in a 10% isotonic solution were examined in two groups of patients with peripheral obstructive arteriopathy. Systemic AP showed no appreciable changes, whereas RAP and Ht fell in direct proportion of the dose given. This effect tended to disappear after 96 hr. Administration of this plasma volume extender 4 days per week is recommended.