Detalhe da pesquisa
1.
Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis.
Mol Genet Metab
; 132(2): 128-138, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33483253
2.
Reduced Shmt2 Expression Impairs Mitochondrial Folate Accumulation and Respiration, and Leads to Uracil Accumulation in Mouse Mitochondrial DNA.
J Nutr
; 151(10): 2882-2893, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34383924
3.
Alterations in Sulfur Amino Acids as Biomarkers of Disease.
J Nutr
; 150(Suppl 1): 2532S-2537S, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33000156
4.
Lessons Learned from Inherited Metabolic Disorders of Sulfur-Containing Amino Acids Metabolism.
J Nutr
; 150(Suppl 1): 2506S-2517S, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33000152
5.
p53 Disruption Increases Uracil Accumulation in DNA of Murine Embryonic Fibroblasts and Leads to Folic Acid-Nonresponsive Neural Tube Defects in Mice.
J Nutr
; 150(7): 1705-1712, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32271909
6.
Taurine alleviates repression of betaine-homocysteine S-methyltransferase and significantly improves the efficacy of long-term betaine treatment in a mouse model of cystathionine ß-synthase-deficient homocystinuria.
FASEB J
; 33(5): 6339-6353, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30768359
7.
Maternal Amino Acid Profiles to Distinguish Constitutionally Small versus Growth-Restricted Fetuses Defined by Doppler Ultrasound: A Pilot Study.
Am J Perinatol
; 37(11): 1084-1093, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32120425
8.
Taurine treatment prevents derangement of the hepatic γ-glutamyl cycle and methylglyoxal metabolism in a mouse model of classical homocystinuria: regulatory crosstalk between thiol and sulfinic acid metabolism.
FASEB J
; 32(3): 1265-1280, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29101223
9.
Biomarkers of oxidative stress, inflammation, and vascular dysfunction in inherited cystathionine ß-synthase deficient homocystinuria and the impact of taurine treatment in a phase 1/2 human clinical trial.
J Inherit Metab Dis
; 42(3): 424-437, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30873612
10.
Folate Deficiency Facilitates Genomic Integration of Human Papillomavirus Type 16 DNA In Vivo in a Novel Mouse Model for Rapid Oncogenic Transformation of Human Keratinocytes.
J Nutr
; 148(3): 389-400, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29546304
11.
Cystathionine beta-synthase deficiency alters hepatic phospholipid and choline metabolism: Post-translational repression of phosphatidylethanolamine N-methyltransferase is a consequence rather than a cause of liver injury in homocystinuria.
Mol Genet Metab
; 120(4): 325-336, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28291718
12.
Identification of ABC transporters acting in vitamin B12 metabolism in Caenorhabditis elegans.
Mol Genet Metab
; 122(4): 160-171, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29153845
13.
Evidence Favoring a Positive Feedback Loop for Physiologic Auto Upregulation of hnRNP-E1 during Prolonged Folate Deficiency in Human Placental Cells.
J Nutr
; 147(4): 482-498, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28250194
14.
Molecular and biochemical investigations of patients with intermediate or severe hyperhomocysteinemia.
Mol Genet Metab
; 117(3): 344-50, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26750749
15.
Hcfc1b, a zebrafish ortholog of HCFC1, regulates craniofacial development by modulating mmachc expression.
Dev Biol
; 396(1): 94-106, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25281006
16.
Vitamin B-12 Status Differs among Pregnant, Lactating, and Control Women with Equivalent Nutrient Intakes.
J Nutr
; 145(7): 1507-14, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25995278
17.
Altered hepatic sulfur metabolism in cystathionine ß-synthase-deficient homocystinuria: regulatory role of taurine on competing cysteine oxidation pathways.
FASEB J
; 28(9): 4044-54, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24891521
18.
Influence of physiologic folate deficiency on human papillomavirus type 16 (HPV16)-harboring human keratinocytes in vitro and in vivo.
J Biol Chem
; 287(15): 12559-77, 2012 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22351779
19.
Cystathionine protects against endoplasmic reticulum stress-induced lipid accumulation, tissue injury, and apoptotic cell death.
J Biol Chem
; 287(38): 31994-2005, 2012 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22854956
20.
Disruption of shmt1 impairs hippocampal neurogenesis and mnemonic function in mice.
J Nutr
; 143(7): 1028-35, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23700346