Detalhe da pesquisa
1.
Regulation of Wnt receptor activity: Implications for therapeutic development in colon cancer.
J Biol Chem
; 296: 100782, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34000297
2.
PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice.
Gastroenterology
; 146(5): 1301-12.e1-10, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24530606
3.
Protein phosphatase PPM1G regulates protein translation and cell growth by dephosphorylating 4E binding protein 1 (4E-BP1).
J Biol Chem
; 288(32): 23225-33, 2013 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23814053
4.
Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer.
bioRxiv
; 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38260423
5.
Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA.
Carcinogenesis
; 33(9): 1782-90, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22696593
6.
mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells.
J Biol Chem
; 286(8): 6510-20, 2011 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21177869
7.
Mutation of the galectin-3 glycan-binding domain (Lgals3-R200S) enhances cortical bone expansion in male mice and trabecular bone mass in female mice.
FEBS Open Bio
; 12(10): 1717-1728, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36062328
8.
Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1.
J Biol Chem
; 285(32): 24987-98, 2010 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20530489
9.
LGR4: Not Just for Wnt Anymore?
Cancer Res
; 81(17): 4397-4398, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34470783
10.
Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer.
Oncogene
; 39(44): 6789-6801, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32973331
11.
De Novo Fatty Acid Synthesis-Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal Cancer.
Mol Cancer Res
; 17(1): 140-152, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30154249
12.
Erbin Suppresses KSR1-Mediated RAS/RAF Signaling and Tumorigenesis in Colorectal Cancer.
Cancer Res
; 78(17): 4839-4852, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29980571
13.
PHLPP negatively regulates cell motility through inhibition of Akt activity and integrin expression in pancreatic cancer cells.
Oncotarget
; 7(7): 7801-15, 2016 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26760962
14.
Downregulation of PHLPP expression contributes to hypoxia-induced resistance to chemotherapy in colon cancer cells.
Mol Cell Biol
; 33(22): 4594-605, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24061475
15.
PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth.
Mol Cell Biol
; 31(24): 4917-27, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21986499
16.
mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.
Cancer Res
; 71(9): 3246-56, 2011 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21430067