Detalhe da pesquisa
1.
Results of a phase II clinical trial of 6-mercaptopurine (6MP) and methotrexate in patients with BRCA-defective tumours.
Br J Cancer
; 122(4): 483-490, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31813938
2.
A phase 1 study to assess the safety, tolerability, and pharmacokinetics of CXD101 in patients with advanced cancer.
Cancer
; 125(1): 99-108, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30332497
3.
Focused Ultrasound Hyperthermia for Targeted Drug Release from Thermosensitive Liposomes: Results from a Phase I Trial.
Radiology
; 291(1): 232-238, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30644817
4.
Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial.
Lancet Oncol
; 19(8): 1027-1039, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30001990
5.
A first-in-human phase I study to determine the maximum tolerated dose of the oral Src/ABL inhibitor AZD0424.
Br J Cancer
; 118(6): 770-776, 2018 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29438361
6.
Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast.
Genes Dev
; 24(23): 2705-16, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21123655
7.
Prebiotic administration normalizes lipopolysaccharide (LPS)-induced anxiety and cortical 5-HT2A receptor and IL1-ß levels in male mice.
Brain Behav Immun
; 52: 120-131, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26476141
8.
Oxidative calcium release from catechol.
Bioorg Med Chem Lett
; 25(7): 1453-4, 2015 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25740160
9.
Systemic inflammation alters central 5-HT function as determined by pharmacological MRI.
Neuroimage
; 75: 177-186, 2013 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23473937
10.
Mechanistic studies of the inactivation of tyrosinase by resorcinol.
Bioorg Med Chem
; 21(5): 1166-73, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23352755
11.
The influence of hydroquinone on tyrosinase kinetics.
Bioorg Med Chem
; 20(14): 4364-70, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22698780
12.
Rapid halogen substitution and dibenzodioxin formation during tyrosinase-catalyzed oxidation of 4-halocatechols.
Chem Res Toxicol
; 24(3): 350-6, 2011 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21306115
13.
Corrigendum to "Systemic inflammation alters central 5-HT function as determined by pharmacological MRI" [Neuroimage 75 (2013) 177-186].
Neuroimage
; 94: 413, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28843644
14.
The influence of catechol structure on the suicide-inactivation of tyrosinase.
Org Biomol Chem
; 7(17): 3388-90, 2009 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19675891
15.
Enhanced fluorescence detection of cis-combretastatins by post-column photolysis.
J Chromatogr A
; 1181(1-2): 162-5, 2008 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18199444
16.
Evidence consistent with the requirement of cresolase activity for suicide inactivation of tyrosinase.
Tohoku J Exp Med
; 216(3): 231-8, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18987457
17.
Radiosensitization In Vivo by Histone Deacetylase Inhibition with No Increase in Early Normal Tissue Radiation Toxicity.
Mol Cancer Ther
; 17(2): 381-392, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28839000
18.
Synthesis and biological properties of bioreductively targeted nitrothienyl prodrugs of combretastatin A-4.
Mol Cancer Ther
; 5(11): 2886-94, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17121936
19.
A phase I pharmacokinetic and translational study of the novel vascular targeting agent combretastatin a-4 phosphate on a single-dose intravenous schedule in patients with advanced cancer.
Cancer Res
; 62(12): 3408-16, 2002 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12067983
20.
ZD6126: a novel vascular-targeting agent that causes selective destruction of tumor vasculature.
Cancer Res
; 62(24): 7247-53, 2002 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12499266