Detalhe da pesquisa
1.
A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system.
Nucleic Acids Res
; 2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38726879
2.
Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
Mol Ther
; 31(6): 1661-1674, 2023 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37177784
3.
Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
Mol Ther
; 31(11): 3355-3356, 2023 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37751745
4.
mRNA nuclear clustering leads to a difference in mutant huntingtin mRNA and protein silencing by siRNAs in vivo.
bioRxiv
; 2024 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38774633
5.
Dendritic amphiphilic siRNA: Selective albumin binding, in vivo efficacy, and low toxicity.
Mol Ther Nucleic Acids
; 34: 102080, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38089931
6.
A programmable dual-targeting di-valent siRNA scaffold supports potent multi-gene modulation in the central nervous system.
bioRxiv
; 2023 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38187561
7.
Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo.
Res Sq
; 2023 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37398145
8.
Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo.
bioRxiv
; 2023 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292886
9.
Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin.
Nat Commun
; 14(1): 7099, 2023 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37925520