Detalhe da pesquisa
1.
Human topoisomerases and their roles in genome stability and organization.
Nat Rev Mol Cell Biol
; 23(6): 407-427, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35228717
2.
XRCC1 prevents toxic PARP1 trapping during DNA base excision repair.
Mol Cell
; 81(14): 3018-3030.e5, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34102106
3.
A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia.
Mol Cell
; 80(6): 1013-1024.e6, 2020 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33338401
4.
BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.
Mol Cell
; 73(6): 1267-1281.e7, 2019 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30704900
5.
Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations.
Mol Cell
; 75(2): 267-283.e12, 2019 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31202576
6.
PARP1 UFMylation ensures the stability of stalled replication forks.
Proc Natl Acad Sci U S A
; 121(18): e2322520121, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38657044
7.
The proofreading exonuclease of leading-strand DNA polymerase epsilon prevents replication fork collapse at broken template strands.
Nucleic Acids Res
; 51(22): 12288-12302, 2023 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37944988
8.
Physiological concentrations of glucocorticoids induce pathological DNA double-strand breaks.
Genes Cells
; 28(1): 53-67, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36415926
9.
Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes.
Mol Cell
; 64(3): 580-592, 2016 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27814490
10.
HTLV-1 bZIP factor impairs DNA mismatch repair system.
Biochem Biophys Res Commun
; 657: 43-49, 2023 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36972660
11.
XRCC1 counteracts poly(ADP ribose)polymerase (PARP) poisons, olaparib and talazoparib, and a clinical alkylating agent, temozolomide, by promoting the removal of trapped PARP1 from broken DNA.
Genes Cells
; 27(5): 331-344, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35194903
12.
Replication-dependent cytotoxicity and Spartan-mediated repair of trapped PARP1-DNA complexes.
Nucleic Acids Res
; 49(18): 10493-10506, 2021 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34551432
13.
The fragility of a structurally diverse duplication block triggers recurrent genomic amplification.
Nucleic Acids Res
; 49(1): 244-256, 2021 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33290559
14.
Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells.
Proc Natl Acad Sci U S A
; 117(25): 14412-14420, 2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32513688
15.
ATAD5 deficiency alters DNA damage metabolism and sensitizes cells to PARP inhibition.
Nucleic Acids Res
; 48(9): 4928-4939, 2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32297953
16.
Genetic evidence for the involvement of mismatch repair proteins, PMS2 and MLH3, in a late step of homologous recombination.
J Biol Chem
; 295(51): 17460-17475, 2020 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33453991
17.
TDP2 suppresses genomic instability induced by androgens in the epithelial cells of prostate glands.
Genes Cells
; 25(7): 450-465, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32277721
18.
Follow-up genotoxicity assessment of Ames-positive/equivocal chemicals using the improved thymidine kinase gene mutation assay in DNA repair-deficient human TK6 cells.
Mutagenesis
; 36(5): 331-338, 2021 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34216473
19.
Correction: The BRCT Domain of PARP-1 Is Required for Immunoglobulin Gene Conversion.
PLoS Biol
; 16(3): e1002621, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29494577
20.
SUMOylation of PCNA by PIAS1 and PIAS4 promotes template switch in the chicken and human B cell lines.
Proc Natl Acad Sci U S A
; 115(50): 12793-12798, 2018 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30487218