RESUMO
INTRODUCTION: The microscopic colitis (MC) is characterized by the presence of aqueous chronic diarrhea (ACD) with inflammatory elements in the colon only detectable by microscopy. OBJECTIVES: To know the prevalence of MC in the group of patients with ACD attending the Endoscopy Service of the British Hospital from Montevideo. MATERIAL AND METHODS: We retrospectively included patients with ACD who were studied by endoscopy during a period of 5 years and the endoscopy was normal or showed minimal alterations. Biopsies in different parts of the colon were taken to this group of patients aiming to diagnose this entity. RESULTS: We included 180 patients, 101 women (56%) and 79 men (44%). No lesion was found in the endoscopy in 67% of them, 27% had a diverticular colopathy and 5% a non-specific colitis. Out of the total number of patients, 9% had a histological study compatible with MC, 82% had lymphocytic colitis (CL) and 18% collagenous colitis (CC), with a ratio between men and women of 1.8:1 and 1:2, respectively. The mean age for the diagnosis was 43 years old in the group of CL and 61 years old in the group of CC. Endoscopic lesions were not found in 94% of patients with MC and only 1 patient presented a non-specific colitis at the endoscopy. The 65% of the remaining patients did not show histological alterations and 26% of them presented non-specific inflammatory changes. CONCLUSIONS: The prevalence of MC in our series was similar to that found in other publications and alterations in the colonic mucosa were not found in most cases. The CL was the most frequent form of presentation and was found at an earlier age than the CC. The CL was more frequent in men. Knowing that the CM is a rare illness in our environment, these findings suggest the importance of taking multiple biopsies from different parts of the colon when patients with ACD are studied.
Assuntos
Colite Microscópica/epidemiologia , Diarreia/epidemiologia , Adulto , Idoso , Doença Crônica , Colite Microscópica/complicações , Colonoscopia , Diarreia/etiologia , Feminino , Humanos , Mucosa Intestinal , Masculino , Pessoa de Meia-Idade , Prevalência , Estudos Retrospectivos , Uruguai/epidemiologia , Adulto JovemAssuntos
Medicina Baseada em Evidências , Refluxo Gastroesofágico/terapia , Alginatos/administração & dosagem , Alginatos/uso terapêutico , Antiácidos/administração & dosagem , Antiácidos/uso terapêutico , Antiulcerosos/administração & dosagem , Antiulcerosos/uso terapêutico , Estudos de Coortes , Consenso , Relação Dose-Resposta a Droga , Quimioterapia Combinada , Endoscopia , Esofagite/tratamento farmacológico , Feminino , Refluxo Gastroesofágico/tratamento farmacológico , Refluxo Gastroesofágico/epidemiologia , Refluxo Gastroesofágico/cirurgia , Humanos , América Latina , Estilo de Vida , Metanálise como Assunto , Obesidade/complicações , Omeprazol/administração & dosagem , Omeprazol/uso terapêutico , Guias de Prática Clínica como Assunto , Prevalência , Inibidores da Bomba de Prótons/uso terapêutico , Fatores de Risco , Fatores de Tempo , Aumento de PesoRESUMO
Se presenta la experiencia inicial del drenaje endoscópico de la vía biliar (DBE) utilizando 2 técnicas: DBE externo con sonda nasobiliar en 2 pacientes y DBE interno o endoprótesis en 3 casos. Las indicaciones fueron, colangitis por litiasis en los 2 casos de DBE externo. El DBE interno se utilizó en un caso de estenosis de vía biliar por neoplasma de páncreas, otro de estenosis de vía biliar por neoplasma de vesícula y un caso de litiasis coledociana con contraindicaciones quirúrgicas. Los resultados iniciales son muy buenos para el DBE externo en las colangitis y DBE interno por neoplasma. Deben evaluarse los resultados a largo plazo de este último grupo