Detalhe da pesquisa
1.
Development of UTX-143, a selective sodium-hydrogen exchange subtype 5 inhibitor, using amiloride as a lead compound.
Bioorg Med Chem
; 99: 117603, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38246115
2.
The membrane-linked adaptor FRS2ß fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis.
Proc Natl Acad Sci U S A
; 118(43)2021 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34663724
3.
m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-ß-induced epithelial-mesenchymal transition of lung cancer cells.
J Biol Chem
; 298(11): 102554, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36183833
4.
ASH2L, a COMPASS core subunit, is involved in the cell invasion and migration of triple-negative breast cancer cells through the epigenetic control of histone H3 lysine 4 methylation.
Biochem Biophys Res Commun
; 669: 19-29, 2023 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37262949
5.
KDM2B is involved in the epigenetic regulation of TGF-ß-induced epithelial-mesenchymal transition in lung and pancreatic cancer cell lines.
J Biol Chem
; 296: 100213, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33779563
6.
The m6A methyltransferase METTL3 contributes to Transforming Growth Factor-beta-induced epithelial-mesenchymal transition of lung cancer cells through the regulation of JUNB.
Biochem Biophys Res Commun
; 524(1): 150-155, 2020 03 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31982139
7.
MEG8 long noncoding RNA contributes to epigenetic progression of the epithelial-mesenchymal transition of lung and pancreatic cancer cells.
J Biol Chem
; 293(47): 18016-18030, 2018 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30262664
8.
MEG3 Long Noncoding RNA Contributes to the Epigenetic Regulation of Epithelial-Mesenchymal Transition in Lung Cancer Cell Lines.
J Biol Chem
; 292(1): 82-99, 2017 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27852821
9.
Epigenetic regulation of epithelial-mesenchymal transition by KDM6A histone demethylase in lung cancer cells.
Biochem Biophys Res Commun
; 490(4): 1407-1413, 2017 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28698146
10.
Genome-wide DNA methylation patterns in LSH mutant reveals de-repression of repeat elements and redundant epigenetic silencing pathways.
Genome Res
; 24(10): 1613-23, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25170028
11.
The ATP binding site of the chromatin remodeling homolog Lsh is required for nucleosome density and de novo DNA methylation at repeat sequences.
Nucleic Acids Res
; 43(3): 1444-55, 2015 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25578963
12.
CG hypomethylation in Lsh-/- mouse embryonic fibroblasts is associated with de novo H3K4me1 formation and altered cellular plasticity.
Proc Natl Acad Sci U S A
; 111(16): 5890-5, 2014 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24711395
13.
Jmjd5 functions as a regulator of p53 signaling during mouse embryogenesis.
Cell Tissue Res
; 363(3): 723-33, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26334721
14.
Jmjd5, an H3K36me2 histone demethylase, modulates embryonic cell proliferation through the regulation of Cdkn1a expression.
Development
; 139(4): 749-59, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22241836
15.
EED regulates epithelial-mesenchymal transition of cancer cells induced by TGF-ß.
Biochem Biophys Res Commun
; 453(1): 124-30, 2014 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25264103
16.
Roles of histone methyl-modifying enzymes in development and progression of cancer.
Cancer Sci
; 104(7): 795-800, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23560485
17.
PLU1 histone demethylase decreases the expression of KAT5 and enhances the invasive activity of the cells.
Biochem J
; 437(3): 555-64, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21574959
18.
Erratum: TGF-ß1 facilitates MT1-MMP-mediated proMMP-9 activation and invasion in oral squamous cell carcinoma cells (BBREP_101072).
Biochem Biophys Rep
; 27: 101093, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34557602
19.
TGF-ß1 facilitates MT1-MMP-mediated proMMP-9 activation and invasion in oral squamous cell carcinoma cells.
Biochem Biophys Rep
; 27: 101072, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34381878
20.
The tumor suppressor Rb and its related Rbl2 genes are regulated by Utx histone demethylase.
Biochem Biophys Res Commun
; 399(2): 238-44, 2010 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20650264