Detalhe da pesquisa
1.
Mitochondrial Dysfunction, Oxidative Stress, and Inter-Organ Miscommunications in T2D Progression.
Int J Mol Sci
; 25(3)2024 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38338783
2.
A Novel Role for DOC2B in Ameliorating Palmitate-Induced Glucose Uptake Dysfunction in Skeletal Muscle Cells via a Mechanism Involving ß-AR Agonism and Cofilin.
Int J Mol Sci
; 25(1)2023 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38203312
3.
Mechanisms by Which Skeletal Muscle Myokines Ameliorate Insulin Resistance.
Int J Mol Sci
; 23(9)2022 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35563026
4.
Conventional and Unconventional Mechanisms by which Exocytosis Proteins Oversee ß-cell Function and Protection.
Int J Mol Sci
; 22(4)2021 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33673206
5.
DOC2B promotes insulin sensitivity in mice via a novel KLC1-dependent mechanism in skeletal muscle.
Diabetologia
; 62(5): 845-859, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30707251
6.
Depletion of the membrane-fusion regulator Munc18c attenuates caerulein hyperstimulation-induced pancreatitis.
J Biol Chem
; 293(7): 2510-2522, 2018 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29284677
7.
Novel approaches to restore beta cell function in prediabetes and type 2 diabetes.
Diabetologia
; 61(9): 1895-1901, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29947922
8.
The actin-related p41ARC subunit contributes to p21-activated kinase-1 (PAK1)-mediated glucose uptake into skeletal muscle cells.
J Biol Chem
; 292(46): 19034-19043, 2017 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28972183
9.
Inflammatory stress of pancreatic beta cells drives release of extracellular heat-shock protein 90α.
Immunology
; 151(2): 198-210, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28190264
10.
Exocytosis proteins as novel targets for diabetes prevention and/or remediation?
Am J Physiol Regul Integr Comp Physiol
; 312(5): R739-R752, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28356294
11.
The p21-activated kinase (PAK1) is involved in diet-induced beta cell mass expansion and survival in mice and human islets.
Diabetologia
; 59(10): 2145-55, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27394663
12.
VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells.
Diabetologia
; 58(11): 2573-81, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26224100
13.
YES, a Src family kinase, is a proximal glucose-specific activator of cell division cycle control protein 42 (Cdc42) in pancreatic islet ß cells.
J Biol Chem
; 289(16): 11476-11487, 2014 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24610809
14.
Fetal hyperglycemia and a high-fat diet contribute to aberrant glucose tolerance and hematopoiesis in adult rats.
Pediatr Res
; 77(2): 316-25, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25412163
15.
Doc2b serves as a scaffolding platform for concurrent binding of multiple Munc18 isoforms in pancreatic islet ß-cells.
Biochem J
; 464(2): 251-8, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25190515
16.
Doc2b enrichment enhances glucose homeostasis in mice via potentiation of insulin secretion and peripheral insulin sensitivity.
Diabetologia
; 57(7): 1476-84, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24705606
17.
Novel roles for insulin receptor (IR) in adipocytes and skeletal muscle cells via new and unexpected substrates.
Cell Mol Life Sci
; 70(16): 2815-34, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23052216
18.
Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion.
PLoS Genet
; 7(10): e1002323, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21998599
19.
Munc18-1 regulates first-phase insulin release by promoting granule docking to multiple syntaxin isoforms.
J Biol Chem
; 287(31): 25821-33, 2012 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22685295
20.
Toward Ameliorating Insulin Resistance: Targeting a Novel PAK1 Signaling Pathway Required for Skeletal Muscle Mitochondrial Function.
Antioxidants (Basel)
; 12(9)2023 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37759961