Detalhe da pesquisa
1.
Design, synthesis and biological evaluation of indane derived GPR40 agoPAMs.
Bioorg Med Chem Lett
; 29(14): 1842-1848, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31109791
2.
GPR40 reduces food intake and body weight through GLP-1.
Am J Physiol Endocrinol Metab
; 313(1): E37-E47, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28292762
3.
Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus.
Bioorg Med Chem Lett
; 27(9): 2069-2073, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28284804
4.
Discovery of orally active hepatoselective glucokinase activators for treatment of Type II Diabetes Mellitus.
Bioorg Med Chem Lett
; 27(9): 2063-2068, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28284809
5.
Seroprevalence of anti-hepatitis E virus antibodies in domestic pigs in Mexico.
BMC Vet Res
; 13(1): 289, 2017 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28934965
6.
SAR exploration at the C-3 position of tetrahydro-ß-carboline sstr3 antagonists.
Bioorg Med Chem Lett
; 26(6): 1529-1535, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26898814
7.
Increase of drug use and genotype 3 in HCV-infected patients from Central West and Northeast Mexico.
Ann Hepatol
; 14(5): 642-51, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26256892
8.
Spontaneous hepatitis C viral clearance and hepatitis C chronic infection are associated with distinct cytokine profiles in Mexican patients.
Mem Inst Oswaldo Cruz
; 110(2): 267-71, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25946254
9.
Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.
CPT Pharmacometrics Syst Pharmacol
; 13(1): 79-92, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37794724
10.
Epidemiology of Hepatitis C Virus in HIV Patients from West Mexico: Implications for Controlling and Preventing Viral Hepatitis.
Pathogens
; 13(5)2024 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38787212
11.
Vericiguat, a novel sGC stimulator: Mechanism of action, clinical, and translational science.
Clin Transl Sci
; 16(12): 2458-2466, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37997225
12.
Assessing QTc Effects of Vericiguat Using Two Different Concentration-QTc Modeling Approaches.
Clin Pharmacokinet
; 62(11): 1639-1648, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37672197
13.
Design of a Rheumatology Transition Clinic for a Resource-Constrained Setting.
Indian J Pediatr
; 90(1): 29-37, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35476251
14.
Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy.
Nat Med
; 11(7): 797-803, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15965483
15.
Population Pharmacokinetics of Vericiguat in Patients With Heart Failure With Reduced Ejection Fraction: An Integrated Analysis.
Clin Pharmacol Ther
; 112(5): 1061-1069, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35841202
16.
Adipose tissue-derived factors: impact on health and disease.
Endocr Rev
; 27(7): 762-78, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17056740
17.
Obesity-associated improvements in metabolic profile through expansion of adipose tissue.
J Clin Invest
; 117(9): 2621-37, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17717599
18.
Visceral fat adipokine secretion is associated with systemic inflammation in obese humans.
Diabetes
; 56(4): 1010-3, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17287468
19.
Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase.
ACS Med Chem Lett
; 9(1): 39-44, 2018 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29348809
20.
Structure-Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs.
ACS Med Chem Lett
; 9(7): 685-690, 2018 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30034601