Pesquisa | BVS CLAP/SMR-OPAS/OMS

1.

Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production.

Ito, Yukitaka; Nakamura, Sou; Sugimoto, Naoshi; Shigemori, Tomohiro; Kato, Yoshikazu; Ohno, Mikiko; Sakuma, Shinya; Ito, Keitaro; Kumon, Hiroki; Hirose, Hidenori; Okamoto, Haruki; Nogawa, Masayuki; Iwasaki, Mio; Kihara, Shunsuke; Fujio, Kosuke; Matsumoto, Takuya; Higashi, Natsumi; Hashimoto, Kazuya; Sawaguchi, Akira; Harimoto, Ken-Ichi; Nakagawa, Masato; Yamamoto, Takuya; Handa, Makoto; Watanabe, Naohide; Nishi, Eiichiro; Arai, Fumihito; Nishimura, Satoshi; Eto, Koji.

Cell ; 174(3): 636-648.e18, 2018 07 26.

Artigo em Inglês | MEDLINE | ID: mdl-30017246

2.

Hemostatic function of cold-stored platelets in a thrombocytopenic rabbit bleeding model.

Nogawa, Masayuki; Watanabe, Naohide; Koike, Toshiyasu; Fukuda, Kanae; Ishiguro, Mariko; Fujino, Hitomi; Hirayama, Junichi; Shiba, Masayuki; Handa, Makoto; Mori, Takehiko; Okamoto, Shinichiro; Miyata, Shigeki; Satake, Masahiro.

Transfusion ; 62(11): 2304-2313, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-36178666

3.

Adoptive cell therapy using tumor-infiltrating lymphocytes for melanoma refractory to immune-checkpoint inhibitors.

Hirai, Ikuko; Funakoshi, Takeru; Kamijuku, Hajime; Fukuda, Keitaro; Mori, Mariko; Sakurai, Masatoshi; Koda, Yuya; Kato, Jun; Mori, Takehiko; Watanabe, Naohide; Noji, Shinobu; Yaguchi, Tomonori; Iwata, Takashi; Ohta, Shigeki; Fujita, Tomonobu; Tanosaki, Ryuji; Handa, Makoto; Okamoto, Shinichiro; Amagai, Masayuki; Kawakami, Yutaka.

Cancer Sci ; 112(8): 3163-3172, 2021 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-34101300

4.

iPLAT1: the first-in-human clinical trial of iPSC-derived platelets as a phase 1 autologous transfusion study.

Sugimoto, Naoshi; Kanda, Junya; Nakamura, Sou; Kitano, Toshiyuki; Hishizawa, Masakatsu; Kondo, Tadakazu; Shimizu, Shin; Shigemasa, Akiko; Hirai, Hideyo; Arai, Yasuyuki; Minami, Manabu; Tada, Harue; Momose, Dai; Koh, Ki-Ryang; Nogawa, Masayuki; Watanabe, Naohide; Okamoto, Shinichiro; Handa, Makoto; Sawaguchi, Akira; Matsuyama, Nobuki; Tanaka, Mitsunobu; Hayashi, Tomoya; Fuchizaki, Akihiro; Tani, Yoshihiko; Takaori-Kondo, Akifumi; Eto, Koji.

Blood ; 140(22): 2398-2402, 2022 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-36112961

5.

Refined methods to evaluate the in vivo hemostatic function and viability of transfused human platelets in rabbit models.

Watanabe, Naohide; Nogawa, Masayuki; Ishiguro, Mariko; Maruyama, Hitomi; Shiba, Masayuki; Satake, Masahiro; Eto, Koji; Handa, Makoto.

Transfusion ; 57(8): 2035-2044, 2017 08.

Artigo em Inglês | MEDLINE | ID: mdl-28681458

6.

Calcium-dependent activation and autolysis of Arabidopsis metacaspase 2d.

Watanabe, Naohide; Lam, Eric.

J Biol Chem ; 286(12): 10027-40, 2011 Mar 25.

Artigo em Inglês | MEDLINE | ID: mdl-21209078

7.

Arabidopsis metacaspase 2d is a positive mediator of cell death induced during biotic and abiotic stresses.

Watanabe, Naohide; Lam, Eric.

Plant J ; 66(6): 969-82, 2011 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-21395887

8.

Production and nonclinical evaluation of an autologous iPSC-derived platelet product for the iPLAT1 clinical trial.

Sugimoto, Naoshi; Nakamura, Sou; Shimizu, Shin; Shigemasa, Akiko; Kanda, Junya; Matsuyama, Nobuki; Tanaka, Mitsunobu; Hayashi, Tomoya; Fuchizaki, Akihiro; Nogawa, Masayuki; Watanabe, Naohide; Okamoto, Shinichiro; Handa, Makoto; Sawaguchi, Akira; Momose, Dai; Koh, Ki-Ryang; Tani, Yoshihiko; Takaori-Kondo, Akifumi; Eto, Koji.

Blood Adv ; 6(23): 6056-6069, 2022 12 13.

Artigo em Inglês | MEDLINE | ID: mdl-36149941

9.

SHD1 is a novel cytokine-inducible, negative feedback regulator of STAT5-dependent transcription.

Nakajima, Hideaki; Tamura, Toshiki; Ito, Miyuki; Shibata, Fumi; Kuroda, Kana; Fukuchi, Yumi; Watanabe, Naohide; Kitamura, Toshio; Ikeda, Yasuo; Handa, Makoto.

Blood ; 113(5): 1027-36, 2009 Jan 29.

Artigo em Inglês | MEDLINE | ID: mdl-18838617

10.

Genome-wide transposon tagging reveals location-dependent effects on transcription and chromatin organization in Arabidopsis.

Rosin, Faye M; Watanabe, Naohide; Cacas, Jean-Luc; Kato, Naohiro; Arroyo, Juana M; Fang, Yuda; May, Bruce; Vaughn, Matthew; Simorowski, Joseph; Ramu, Umamaheswari; McCombie, Richard W; Spector, David L; Martienssen, Robert A; Lam, Eric.

Plant J ; 55(3): 514-25, 2008 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-18410481

11.

Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3.

Han, Jaewon; Lim, Chinten James; Watanabe, Naohide; Soriani, Alessandra; Ratnikov, Boris; Calderwood, David A; Puzon-McLaughlin, Wilma; Lafuente, Esther M; Boussiotis, Vassiliki A; Shattil, Sanford J; Ginsberg, Mark H.

Curr Biol ; 16(18): 1796-806, 2006 Sep 19.

Artigo em Inglês | MEDLINE | ID: mdl-16979556

12.

Generation of megakaryocytes and platelets from human subcutaneous adipose tissues.

Matsubara, Yumiko; Saito, Emi; Suzuki, Hidenori; Watanabe, Naohide; Murata, Mitsuru; Ikeda, Yasuo.

Biochem Biophys Res Commun ; 378(4): 716-20, 2009 Jan 23.

Artigo em Inglês | MEDLINE | ID: mdl-19059379

13.

Bax Inhibitor-1, a conserved cell death suppressor, is a key molecular switch downstream from a variety of biotic and abiotic stress signals in plants.

Watanabe, Naohide; Lam, Eric.

Int J Mol Sci ; 10(7): 3149-3167, 2009 Jul 10.

Artigo em Inglês | MEDLINE | ID: mdl-19742129

14.

Moonlighting vacuolar protease: multiple jobs for a busy protein.

Rosin, Faye M; Watanabe, Naohide; Lam, Eric.

Trends Plant Sci ; 10(11): 516-8, 2005 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-16202638

15.

Analyzing the mechanism of Rap1 activation in platelets: Rap1 activation is related to the release reaction mediated through the collagen receptor GPVI.

Jung, Stephanie M; Ohnuma, Masaaki; Watanabe, Naohide; Sonoda, Mamiko; Handa, Makoto; Moroi, Masaaki.

Thromb Res ; 118(4): 509-21, 2006.

Artigo em Inglês | MEDLINE | ID: mdl-16380154

16.

[RIAM: bridge between Rap1 and integrin].

Watanabe, Naohide.

Rinsho Ketsueki ; 51(6): 377-83, 2010 Jun.

Artigo em Japonês | MEDLINE | ID: mdl-20622482

17.

[Red cell autoantibodies].

Watanabe, Naohide; Handa, Makoto.

Nihon Rinsho ; 68 Suppl 6: 687-90, 2010 Jun.

Artigo em Japonês | MEDLINE | ID: mdl-20942164

18.

[Anti-platelet autoantibodies].

Watanabe, Naohide; Handa, Makoto.

Nihon Rinsho ; 68 Suppl 6: 691-3, 2010 Jun.

Artigo em Japonês | MEDLINE | ID: mdl-20942165

19.

Flagellin from an incompatible strain of Acidovorax avenae mediates H2O2 generation accompanying hypersensitive cell death and expression of PAL, Cht-1, and PBZ1, but not of Lox in rice.

Tanaka, Noriko; Che, Fang-Sik; Watanabe, Naohide; Fujiwara, Satsuki; Takayama, Seiji; Isogai, Akira.

Mol Plant Microbe Interact ; 16(5): 422-8, 2003 May.

Artigo em Inglês | MEDLINE | ID: mdl-12744513

20.

A novel polymorphism, 70Leu/Phe, disrupts a consensus Leu residue within the leucine-rich repeat sequence of platelet glycoprotein Ibalpha.

Matsubara, Yumiko; Murata, Mitsuru; Moriki, Takanori; Yokoyama, Kenji; Watanabe, Naohide; Nakajima, Hideaki; Handa, Makoto; Kawano, Koichi; Aoki, Nobuo; Yoshino, Hideaki; Ikeda, Yasuo.

Thromb Haemost ; 87(5): 867-72, 2002 May.

Artigo em Inglês | MEDLINE | ID: mdl-12038791

BVS CLAP/SMR-OPAS/OMS

Centro Latino Americano de Perinatologia, Saúde da Mulher e Reprodutiva

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Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production.

Hemostatic function of cold-stored platelets in a thrombocytopenic rabbit bleeding model.

Adoptive cell therapy using tumor-infiltrating lymphocytes for melanoma refractory to immune-checkpoint inhibitors.

iPLAT1: the first-in-human clinical trial of iPSC-derived platelets as a phase 1 autologous transfusion study.

Refined methods to evaluate the in vivo hemostatic function and viability of transfused human platelets in rabbit models.

Calcium-dependent activation and autolysis of Arabidopsis metacaspase 2d.

Arabidopsis metacaspase 2d is a positive mediator of cell death induced during biotic and abiotic stresses.

Production and nonclinical evaluation of an autologous iPSC-derived platelet product for the iPLAT1 clinical trial.

SHD1 is a novel cytokine-inducible, negative feedback regulator of STAT5-dependent transcription.

Genome-wide transposon tagging reveals location-dependent effects on transcription and chromatin organization in Arabidopsis.

Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3.

Generation of megakaryocytes and platelets from human subcutaneous adipose tissues.

Bax Inhibitor-1, a conserved cell death suppressor, is a key molecular switch downstream from a variety of biotic and abiotic stress signals in plants.

Moonlighting vacuolar protease: multiple jobs for a busy protein.

Analyzing the mechanism of Rap1 activation in platelets: Rap1 activation is related to the release reaction mediated through the collagen receptor GPVI.

[RIAM: bridge between Rap1 and integrin].

[Red cell autoantibodies].

[Anti-platelet autoantibodies].

Flagellin from an incompatible strain of Acidovorax avenae mediates H2O2 generation accompanying hypersensitive cell death and expression of PAL, Cht-1, and PBZ1, but not of Lox in rice.

A novel polymorphism, 70Leu/Phe, disrupts a consensus Leu residue within the leucine-rich repeat sequence of platelet glycoprotein Ibalpha.