Detalhe da pesquisa
1.
Characterization of functionally deficient SIM2 variants found in patients with neurological phenotypes.
Biochem J
; 479(13): 1441-1454, 2022 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35730699
2.
HIF has Biff - Crosstalk between HIF1a and the family of bHLH/PAS proteins.
Exp Cell Res
; 356(2): 141-145, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28366537
3.
Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel.
J Cell Sci
; 128(2): 225-31, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25413349
4.
Regulation of the neuronal transcription factor NPAS4 by REST and microRNAs.
Biochim Biophys Acta
; 1839(1): 13-24, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24291638
5.
Characterization of human variants in obesity-related SIM1 protein identifies a hot-spot for dimerization with the partner protein ARNT2.
Biochem J
; 461(3): 403-12, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24814368
6.
Reciprocal regulation of the basic helix-loop-helix/Per-Arnt-Sim partner proteins, Arnt and Arnt2, during neuronal differentiation.
Nucleic Acids Res
; 41(11): 5626-38, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23599003
7.
Identification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR.
Nucleic Acids Res
; 39(9): 3695-709, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21245039
8.
NanoFIRE: A NanoLuciferase and Fluorescent Integrated Reporter Element for Robust and Sensitive Investigation of HIF and Other Signalling Pathways.
Biomolecules
; 13(10)2023 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37892227
9.
Proteoliposomes reconstituted with human aquaporin-1 reveal novel single-ion-channel properties.
Biophys Rep (N Y)
; 3(1): 100100, 2023 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36949749
10.
Xenobiotics and loss of cell adhesion drive distinct transcriptional outcomes by aryl hydrocarbon receptor signaling.
Mol Pharmacol
; 82(6): 1082-93, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22936816
11.
Sulfonation and phosphorylation of regions of the dioxin receptor susceptible to methionine modifications.
Mol Cell Proteomics
; 8(4): 706-19, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19059900
12.
Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.
Proc Natl Acad Sci U S A
; 105(9): 3368-73, 2008 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-18299578
13.
Molecular characterisation of rare loss-of-function NPAS3 and NPAS4 variants identified in individuals with neurodevelopmental disorders.
Sci Rep
; 11(1): 6602, 2021 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33758288
14.
Amino acid substitutions in the aryl hydrocarbon receptor ligand binding domain reveal YH439 as an atypical AhR activator.
Mol Pharmacol
; 77(6): 1037-46, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20231332
15.
The bHLH/Per-Arnt-Sim transcription factor SIM2 regulates muscle transcript myomesin2 via a novel, non-canonical E-box sequence.
Nucleic Acids Res
; 36(11): 3716-27, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18480125
16.
Structural Models for the Dynamic Effects of Loss-of-Function Variants in the Human SIM1 Protein Transcriptional Activation Domain.
Biomolecules
; 10(9)2020 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32932609
17.
Functional Analysis of the SIM1 Variant p.G715V in 2 Patients With Obesity.
J Clin Endocrinol Metab
; 105(1)2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31872862
18.
The dioxin (aryl hydrocarbon) receptor as a model for adaptive responses of bHLH/PAS transcription factors.
FEBS Lett
; 581(19): 3616-25, 2007 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-17459381
19.
Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety.
Mol Metab
; 6(11): 1419-1428, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29107289
20.
MAGED1 is a novel regulator of a select subset of bHLH PAS transcription factors.
FEBS J
; 283(18): 3488-502, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27472814