Detalhe da pesquisa
1.
mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient.
Cell
; 171(3): 642-654.e12, 2017 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29053970
2.
The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway.
Cell
; 165(1): 153-164, 2016 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26972053
3.
Induction of DEPP1 by HIF Mediates Multiple Hallmarks of Ischemic Cardiomyopathy.
Circulation
; 2024 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38881449
4.
KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.
Nature
; 543(7645): 438-442, 2017 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28199306
5.
Expanding the Therapeutic World of Tryptophan Metabolism.
Circulation
; 145(24): 1799-1802, 2022 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35696459
6.
Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy.
Proc Natl Acad Sci U S A
; 109(43): E2939-48, 2012 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23019585
7.
Mitochondrial remodeling and ischemic protection by G protein-coupled receptor 35 agonists.
Science
; 377(6606): 621-629, 2022 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35926043
8.
A PEROXO-Tag Enables Rapid Isolation of Peroxisomes from Human Cells.
iScience
; 23(5): 101109, 2020 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32417403
9.
NUFIP1 is a ribosome receptor for starvation-induced ribophagy.
Science
; 360(6390): 751-758, 2018 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29700228
10.
Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates.
Elife
; 72018 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29745899
11.
SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism.
Science
; 362(6416)2018 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30442778
12.
Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes.
Science
; 358(6364): 807-813, 2017 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29074583
13.
Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.
Science
; 347(6218): 188-94, 2015 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25567906
14.
Supramolecular nanoparticles that target phosphoinositide-3-kinase overcome insulin resistance and exert pronounced antitumor efficacy.
Cancer Res
; 73(23): 6987-97, 2013 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24121488
15.
Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.
Cancer Cell
; 24(6): 751-65, 2013 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24332043
16.
"Take it up a NOTCH": novel strategies for cancer therapy.
Cell Cycle
; 12(2): 191-2, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23287472