Detalhe da pesquisa
1.
NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation.
Int J Mol Sci
; 24(9)2023 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37175412
2.
PAICS/DYRK3 Multienzyme Interactions as Coregulators of Purinosome Formation and Metabolism on Radioresistance in Oral Squamous Cell Carcinoma.
Int J Mol Sci
; 24(24)2023 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38139175
3.
Role of GDF15/MAPK14 Axis in Chondrocyte Senescence as a Novel Senomorphic Agent in Osteoarthritis.
Int J Mol Sci
; 23(13)2022 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35806043
4.
Targeting the SREBP-1/Hsa-Mir-497/SCAP/FASN Oncometabolic Axis Inhibits the Cancer Stem-like and Chemoresistant Phenotype of Non-Small Cell Lung Carcinoma Cells.
Int J Mol Sci
; 23(13)2022 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35806291
5.
HNMT Upregulation Induces Cancer Stem Cell Formation and Confers Protection against Oxidative Stress through Interaction with HER2 in Non-Small-Cell Lung Cancer.
Int J Mol Sci
; 23(3)2022 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163585
6.
Novel NFκB Inhibitor SC75741 Mitigates Chondrocyte Degradation and Prevents Activated Fibroblast Transformation by Modulating miR-21/GDF-5/SOX5 Signaling.
Int J Mol Sci
; 22(20)2021 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34681754
7.
4-Acetyl-Antroquinonol B Improves the Sensitization of Cetuximab on Both Kras Mutant and Wild Type Colorectal Cancer by Modulating the Expression of Ras/Raf/miR-193a-3p Signaling Axis.
Int J Mol Sci
; 22(14)2021 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34299137
8.
PDK1 Inhibitor BX795 Improves Cisplatin and Radio-Efficacy in Oral Squamous Cell Carcinoma by Downregulating the PDK1/CD47/Akt-Mediated Glycolysis Signaling Pathway.
Int J Mol Sci
; 22(21)2021 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34768921
9.
The E3 Ubiquitin Ligase NEDD4-1 Mediates Temozolomide-Resistant Glioblastoma through PTEN Attenuation and Redox Imbalance in Nrf2-HO-1 Axis.
Int J Mol Sci
; 22(19)2021 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34638586
10.
In-Silico Evaluation of Genetic Alterations in Ovarian Carcinoma and Therapeutic Efficacy of NSC777201, as a Novel Multi-Target Agent for TTK, NEK2, and CDK1.
Int J Mol Sci
; 22(11)2021 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34072728
11.
Ovatodiolide, isolated from Anisomeles indica, suppresses bladder carcinogenesis through suppression of mTOR/ß-catenin/CDK6 and exosomal miR-21 derived from M2 tumor-associated macrophages.
Toxicol Appl Pharmacol
; 401: 115109, 2020 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32544403
12.
Notopterol mitigates IL-1ß-triggered pyroptosis by blocking NLRP3 inflammasome via the JAK2/NF-kB/hsa-miR-4282 route in osteoarthritis.
Heliyon
; 10(6): e28094, 2024 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38532994
13.
Underlying mechanisms of novel cuproptosis-related dihydrolipoamide branched-chain transacylase E2 (DBT) signature in sunitinib-resistant clear-cell renal cell carcinoma.
Aging (Albany NY)
; 16(3): 2679-2701, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38305803
14.
PROX1 interaction with α-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance.
Aging (Albany NY)
; 16(2): 1620-1639, 2024 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38244581
15.
Synergistic disruption of BTK and BCL-2 causes apoptosis while inducing ferroptosis in double-hit lymphoma.
Eur J Pharmacol
; 943: 175526, 2023 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36693553
16.
Furanocoumarin Notopterol: Inhibition of Hepatocellular Carcinogenesis through Suppression of Cancer Stemness Signaling and Induction of Oxidative Stress-Associated Cell Death.
Nutrients
; 15(11)2023 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37299411
17.
Tumor-Associated Macrophages Affect the Tumor Microenvironment and Radioresistance via the Upregulation of CXCL6/CXCR2 in Hepatocellular Carcinoma.
Biomedicines
; 11(7)2023 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37509721
18.
Therapeutic targeting of hepatocellular carcinoma cells with antrocinol, a novel, dual-specificity, small-molecule inhibitor of the KRAS and ERK oncogenic signaling pathways.
Chem Biol Interact
; 370: 110329, 2023 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36565974
19.
Correction: Chen et al. Hydroxychloroquine (HCQ) Modulates Autophagy and Oxidative DNA Damage Stress in Hepatocellular Carcinoma to Overcome Sorafenib Resistance via TLR9/SOD1/hsa-miR-30a-5p/Beclin-1 Axis. Cancers 2021, 13, 3227.
Cancers (Basel)
; 15(4)2023 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36831696
20.
Exosomal miR-21 determines lung-to-brain metastasis specificity through the DGKB/ERK axis within the tumor microenvironment.
Life Sci
; 329: 121945, 2023 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37454756