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Clin Exp Pharmacol Physiol ; 44 Suppl 1: 86-92, 2017 12.
Artigo em Inglês | MEDLINE | ID: mdl-28556290

RESUMO

The present study aimed to investigate the relationship between normal serum concentrations of thyrotropin (TSH) and urinary incontinence (IU), urinary infections, and quality of life in old women. Euthyroid post-menopausal women without sarcopenia, estrogen replacement, emotional illness, and/or cancer were enrolled as participants. Anthropometric indicators, serum glucose and estradiol, and thyroid profile were measured. Sociodemographic, clinical, physical activity, and quality of life (SF-36) surveys were applied. One-hour pad test and International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) were used to determine UI. Urinalysis was also done. In agreement with results from the pad test (cut-off point ≥1.4 g), the ICIQ-SF reveled approximately 50% of incontinent women. A high percentage of women had moderate-high bacteriuria and urinary infections. Logistic regression analysis showed that age is a risk factor for both UI and urinary infection. Diabetes, number of pregnancies or childbirths, urinary infections, and bacteriuria did not influence the presence of UI. To allocate women into four groups according to their age (<65 or ≥65 years old) and TSH concentrations (0.3-1.9 or 2-10 µUI/mL), we found that moderate-to-high normal levels of TSH is a risk factor for UI and a worse quality of life in the oldest women. Our results highlight the profit of measuring TSH concentrations in post-menopausal women.


Assuntos
Qualidade de Vida , Tireotropina/sangue , Incontinência Urinária/sangue , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Biomarcadores/sangue , Biomarcadores/urina , Feminino , Nível de Saúde , Humanos , Saúde Mental , Pessoa de Meia-Idade , Pós-Menopausa/sangue , Fatores de Risco , Fatores Sexuais , Regulação para Cima , Incontinência Urinária/diagnóstico , Incontinência Urinária/etiologia , Incontinência Urinária/psicologia , Infecções Urinárias/sangue , Infecções Urinárias/microbiologia , Infecções Urinárias/psicologia
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