Detalhe da pesquisa
1.
A naturally inspired antibiotic to target multidrug-resistant pathogens.
Nature
; 601(7894): 606-611, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34987225
2.
Normalizing granuloma vasculature and matrix improves drug delivery and reduces bacterial burden in tuberculosis-infected rabbits.
Proc Natl Acad Sci U S A
; 121(14): e2321336121, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38530888
3.
Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy.
Proc Natl Acad Sci U S A
; 119(15): e2201632119, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35380903
4.
Targeting Mycobacterium tuberculosis response to environmental cues for the development of effective antitubercular drugs.
PLoS Biol
; 19(7): e3001355, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34319985
5.
Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F420H2-dependent reduction.
Proc Natl Acad Sci U S A
; 118(25)2021 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34161270
6.
Staphylococcal ClpXP protease targets the cellular antioxidant system to eliminate fitness-compromised cells in stationary phase.
Proc Natl Acad Sci U S A
; 118(47)2021 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34782466
7.
Neural oscillatory activity serving sensorimotor control is predicted by superoxide-sensitive mitochondrial redox environments.
Proc Natl Acad Sci U S A
; 118(43)2021 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34686594
8.
Activity of Oral Tebipenem-Avibactam in a Mouse Model of Mycobacterium abscessus Lung Infection.
Antimicrob Agents Chemother
; 67(2): e0145922, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36688684
9.
Lung microenvironments harbor Mycobacterium tuberculosis phenotypes with distinct treatment responses.
Antimicrob Agents Chemother
; 67(9): e0028423, 2023 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37565762
10.
Drug distribution and efficacy of the DprE1 inhibitor BTZ-043 in the C3HeB/FeJ mouse tuberculosis model.
Antimicrob Agents Chemother
; 67(11): e0059723, 2023 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37791784
11.
Mitochondrial redox environments predict sensorimotor brain-behavior dynamics in adults with HIV.
Brain Behav Immun
; 107: 265-275, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36272499
12.
Elevated CRP and TNF-α levels are associated with blunted neural oscillations serving fluid intelligence.
Brain Behav Immun
; 114: 430-437, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37716379
13.
A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation.
Cell
; 133(3): 462-74, 2008 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18455987
14.
Mycobacterium tuberculosis DprE1 Inhibitor OPC-167832 Is Active against Mycobacterium abscessus In Vitro.
Antimicrob Agents Chemother
; 66(12): e0123722, 2022 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36350151
15.
Strongly Bactericidal All-Oral ß-Lactam Combinations for the Treatment of Mycobacterium abscessus Lung Disease.
Antimicrob Agents Chemother
; 66(9): e0079022, 2022 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36047786
16.
Cyclohexyl-griselimycin Is Active against Mycobacterium abscessus in Mice.
Antimicrob Agents Chemother
; 66(1): e0140021, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34723632
17.
Novel Regimens of Bedaquiline-Pyrazinamide Combined with Moxifloxacin, Rifabutin, Delamanid and/or OPC-167832 in Murine Tuberculosis Models.
Antimicrob Agents Chemother
; 66(4): e0239821, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35315690
18.
Activity of Tricyclic Pyrrolopyrimidine Gyrase B Inhibitor against Mycobacterium abscessus.
Antimicrob Agents Chemother
; 66(9): e0066922, 2022 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36005813
19.
A Rabbit Model to Study Antibiotic Penetration at the Site of Infection for Nontuberculous Mycobacterial Lung Disease: Macrolide Case Study.
Antimicrob Agents Chemother
; 66(3): e0221221, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35099272
20.
A Novel Oral GyrB/ParE Dual Binding Inhibitor Effective against Multidrug-Resistant Neisseria gonorrhoeae and Other High-Threat Pathogens.
Antimicrob Agents Chemother
; 66(9): e0041422, 2022 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35972242