Detalhe da pesquisa
1.
Evaluation of [18F]fluoroestradiol and ChRERα as a gene expression PET reporter system in rhesus monkey brain.
Mol Ther
; 2024 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38796702
2.
In vivo evaluation of a novel 18F-labeled PET radioligand for translocator protein 18 kDa (TSPO) in monkey brain.
Eur J Nucl Med Mol Imaging
; 50(10): 2962-2970, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37249618
3.
PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study.
J Neuroinflammation
; 17(1): 140, 2020 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32359360
4.
First-in-human evaluation of [11C]PS13, a novel PET radioligand, to quantify cyclooxygenase-1 in the brain.
Eur J Nucl Med Mol Imaging
; 47(13): 3143-3151, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32399622
5.
Neuroinflammation in neocortical epilepsy measured by PET imaging of translocator protein.
Epilepsia
; 60(6): 1248-1254, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31144767
6.
2-(4-Methylsulfonylphenyl)pyrimidines as Prospective Radioligands for Imaging Cyclooxygenase-2 with PET-Synthesis, Triage, and Radiolabeling.
Molecules
; 23(11)2018 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30400142
7.
[O-methyl-11C]N-(4-(4-(3-Chloro-2-methoxyphenyl)-piperazin-1-yl)butyl)-1H-indole-2-carboxamide ([11C]BAK4-51) Is an Efflux Transporter Substrate and Ineffective for PET Imaging of Brain D3 Receptors in Rodents and Monkey.
Molecules
; 23(11)2018 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30360553
8.
(18)F-FCWAY, a serotonin 1A receptor radioligand, is a substrate for efflux transport at the human blood-brain barrier.
Neuroimage
; 138: 134-140, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27211474
9.
The Inhibitor Ko143 Is Not Specific for ABCG2.
J Pharmacol Exp Ther
; 354(3): 384-93, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26148857
10.
In vitro and in vivo evaluation of (11)C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors.
Neuroimage
; 84: 733-41, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24076222
11.
Retest imaging of [11C]NOP-1A binding to nociceptin/orphanin FQ peptide (NOP) receptors in the brain of healthy humans.
Neuroimage
; 87: 89-95, 2014 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24225488
12.
Evaluation in monkey of two candidate PET radioligands, [11 C]RX-1 and [18 F]RX-2, for imaging brain 5-HT4 receptors.
Synapse
; 68(12): 613-623, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25088028
13.
In vivo radioligand binding to translocator protein correlates with severity of Alzheimer's disease.
Brain
; 136(Pt 7): 2228-38, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23775979
14.
Lysosomal trapping of a radiolabeled substrate of P-glycoprotein as a mechanism for signal amplification in PET.
Proc Natl Acad Sci U S A
; 108(6): 2593-8, 2011 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21262843
15.
Robust Quantification of Phosphodiesterase-4D in Monkey Brain with PET and 11C-Labeled Radioligands That Avoid Radiometabolite Contamination.
J Nucl Med
; 65(5): 788-793, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38423785
16.
Synthesis and preclinical evaluation of [11C]uPSEM792 for PSAM4-GlyR based chemogenetics.
Sci Rep
; 14(1): 1886, 2024 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38253691
17.
Evaluation in vitro and in animals of a new 11C-labeled PET radioligand for metabotropic glutamate receptors 1 in brain.
Eur J Nucl Med Mol Imaging
; 40(2): 245-53, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23135321
18.
Candidate 3-benzazepine-1-ol type GluN2B receptor radioligands (11C-NR2B-Me enantiomers) have high binding in cerebellum but not to σ1 receptors.
EJNMMI Res
; 13(1): 28, 2023 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37017827
19.
Discovery of a High-Affinity Fluoromethyl Analog of [11C]5-Cyano-N-(4-(4-methylpiperazin-1-yl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide ([11C]CPPC) and Their Comparison in Mouse and Monkey as Colony-Stimulating Factor 1 Receptor Positron Emission Tomography Radioligands.
ACS Pharmacol Transl Sci
; 6(4): 614-632, 2023 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37082755
20.
Whole-Body PET Imaging in Humans Shows That 11C-PS13 Is Selective for Cyclooxygenase-1 and Can Measure the In Vivo Potency of Nonsteroidal Antiinflammatory Drugs.
J Nucl Med
; 64(1): 159-164, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35798558