Detalhe da pesquisa
1.
Loss of nuclear UBE3A activity is the predominant cause of Angelman syndrome in individuals carrying UBE3A missense mutations.
Hum Mol Genet
; 30(6): 430-442, 2021 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33607653
2.
Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model.
Gut
; 71(11): 2266-2283, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35074907
3.
SENP6 regulates localization and nuclear condensation of DNA damage response proteins by group deSUMOylation.
Nat Commun
; 14(1): 5893, 2023 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37735495
4.
Inhibition of SUMOylation enhances DNA hypomethylating drug efficacy to reduce outgrowth of hematopoietic malignancies.
Leukemia
; 37(4): 864-876, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36792656
5.
Mono-ubiquitination of Rabphilin 3A by UBE3A serves a non-degradative function.
Sci Rep
; 11(1): 3007, 2021 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33542309