Detalhe da pesquisa
1.
Dabigatran Reversal With Idarucizumab in Patients Requiring Urgent Surgery: A Subanalysis of the RE-VERSE AD Study.
Ann Surg
; 274(3): e204-e211, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31599808
2.
Idarucizumab for Dabigatran Reversal in the Management of Patients With Gastrointestinal Bleeding.
Circulation
; 139(6): 748-756, 2019 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30586692
3.
Idarucizumab for Dabigatran Reversal - Full Cohort Analysis.
N Engl J Med
; 377(5): 431-441, 2017 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28693366
4.
Idarucizumab, but not procoagulant concentrates, fully restores dabigatran-altered platelet and fibrin components of hemostasis.
Transfusion
; 59(7): 2436-2445, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30946491
5.
Cerebral Microbleeds in Murine Amyloid Angiopathy: Natural Course and Anticoagulant Effects.
Stroke
; 48(8): 2248-2254, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28706123
6.
Safety, tolerability, and efficacy of idarucizumab for the reversal of the anticoagulant effect of dabigatran in healthy male volunteers: a randomised, placebo-controlled, double-blind phase 1 trial.
Lancet
; 386(9994): 680-90, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26088268
7.
Idarucizumab Improves Outcome in Murine Brain Hemorrhage Related to Dabigatran.
Ann Neurol
; 78(1): 137-41, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25899749
8.
Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease.
Blood
; 123(11): 1747-56, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24449213
9.
Idarucizumab, a specific reversal agent for dabigatran: mode of action, pharmacokinetics and pharmacodynamics, and safety and efficacy in phase 1 subjects.
Am J Emerg Med
; 34(11S): 26-32, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27707528
10.
Characterization of thrombin-bound dabigatran effects on protease-activated receptor-1 expression and signaling in vitro.
Mol Pharmacol
; 88(1): 95-105, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25934730
11.
A specific antidote for dabigatran: functional and structural characterization.
Blood
; 121(18): 3554-62, 2013 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23476049
12.
Prothrombin Complex Concentrate Is Effective in Treating the Anticoagulant Effects of Dabigatran in a Porcine Polytrauma Model.
Anesthesiology
; 123(6): 1350-61, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26414500
13.
Reversal of dabigatran-induced bleeding by coagulation factor concentrates in a rat-tail bleeding model and lack of effect on assays of coagulation.
Anesthesiology
; 120(6): 1429-40, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24714118
14.
Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex-vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model.
Crit Care
; 18(1): R27, 2014 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24499559
15.
Impact of Rabeprazole on APO-Dabigatran Exposure in Healthy Volunteers.
CJC Open
; 5(1): 1-7, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36700178
16.
Antiinflammatory and antifibrotic effects of the oral direct thrombin inhibitor dabigatran etexilate in a murine model of interstitial lung disease.
Arthritis Rheum
; 63(5): 1416-25, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21312187
17.
Switching from enoxaparin to dabigatran etexilate: pharmacokinetics, pharmacodynamics, and safety profile.
Eur J Clin Pharmacol
; 68(5): 607-16, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22252796
18.
Idarucizumab: The Antidote for Reversal of Dabigatran.
Circulation
; 132(25): 2412-22, 2015 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26700008
19.
Hemostatic therapy in experimental intracerebral hemorrhage associated with the direct thrombin inhibitor dabigatran.
Stroke
; 42(12): 3594-9, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21998060
20.
Dabigatran: an oral novel potent reversible nonpeptide inhibitor of thrombin.
Arterioscler Thromb Vasc Biol
; 30(10): 1885-9, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20671233