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1.
Nano Lett ; 24(2): 708-714, 2024 Jan 17.
Artigo em Inglês | MEDLINE | ID: mdl-38165767

RESUMO

Angle-dependent next-generation displays have potential applications in 3D stereoscopic and head-mounted displays, image combiners, and encryption for augmented reality (AR) and security. Metasurfaces enable such exceptional functionalities with groundbreaking achievements in efficient displays over the past decades. However, limitations in angular dispersion control make them unfit for numerous nanophotonic applications. Here, we propose a spin-selective angle-dependent all-dielectric metasurface with a unique design strategy to manifest distinct phase information at different incident angles of light. As a proof of concept, the phase masks of two images are encoded into the metasurface and projected at the desired focal plane under different angles of left circularly polarized (LCP) light. Specifically, the proposed multifunctional metasurface generates two distinct holographic images under LCP illumination at angles of +35 and -35°. The presented holographic displays may provide a feasible route toward multifunctional meta-devices for potential AR displays, encrypted imaging, and information storage applications.

2.
Small ; : e2403156, 2024 Jun 14.
Artigo em Inglês | MEDLINE | ID: mdl-38874058

RESUMO

Energy-efficient glass windows are pivotal in modern infrastructure striving toward the "Zero energy" concept. Electrochromic (EC) energy storage devices emerge as a promising alternative to conventional glass, yet their widespread commercialization is impeded by high costs and dependence on external power sources. Addressing this, redox potential-based self-powered electrochromic (RP-SPEC) devices are introduced leveraging established EC materials like tungsten oxide (WO3) and vanadium-doped nickel oxide (V-NiO) along with aluminum (Al) as an anode. These devices produce open circuit voltages (OCV) exceeding ±0.3 V, enabling autonomous operation for multiple cycles. The WO3 film exhibits 1% transmission and 88% modulation in the colored state at 550 nm with a mere 260 nm thickness. The redox interactions facilitate coloring and bleaching cycles without external power, while photo-charging rejuvenates the system. Notably, the inherent voltages of the RP-SPEC device offer dual functionality, powering electronic devices for up to 81 h. Large-area (≈28 cm2) device feasibility is demonstrated, paving the way for industrial adoption. The RP-SPEC device promises to revolutionize smart window technology by offering both energy efficiency and autonomous operation, thus advancing sustainable infrastructure.

3.
Small ; 20(2): e2305327, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37670556

RESUMO

Low-cost fabric-based top-emitting polymer light-emitting devices (Fa-TPLEDs) have aroused increasing attention due to their remarkable potential applications in wearable displays. However, it is still challenging to realize efficient all-solution-processed devices from bottom electrodes to top electrodes with large-scale fabrication. Here, a smooth reflective Ag cathode integrated on fabric by one-step silver mirror reaction and a composite transparent anode of polydimethylsiloxane/silver nanowires/poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) via a water-assisted peeling method are presented, both of which possess excellent optoelectrical properties and robust mechanical flexibility. The Fa-TPLEDs are constructed by spin-coating functional layers on the bottom reflective cathodes and laminating the top transparent anodes. The Fa-TPLEDs show a current efficiency of 16.3 cd A-1 , an external quantum efficiency of 4.9% and angle-independent electroluminescence spectra. In addition, the Fa-TPLEDs possess excellent mechanical stability, maintaining a current efficiency of 14.3 cd A-1 after 200 bending cycles at a radius of 4 mm. The results demonstrate that the integration of solution-processed reflective cathodes and transparent anodes sheds light on a new avenue to construct low-cost and efficient fabric-based devices, showing great potential applications in emerging smart flexible/wearable electronics.

4.
Environ Sci Technol ; 58(28): 12400-12408, 2024 Jul 16.
Artigo em Inglês | MEDLINE | ID: mdl-38967412

RESUMO

Liquid crystal monomers (LCMs) are biphenyl- or cyclohexane-based organic chemicals used in electronic digital displays, and several of them possess bioaccumulative and toxic properties. Little is known about their occurrence in indoor dust from the United States. We analyzed 60 LCMs in 104 residential indoor dust samples collected from 16 states across the United States. Forty-seven of 60 LCMs were detected in dust samples at a median ∑LCM concentration of 402 ng/g (range: not detected to 4300 ng/g). Trans-4-propylcyclohexyl trans,trans-4'-propylbicyclohexyl-4-carboxylate (MPVBC) and (trans,trans)-4-fluorophenyl 4'-pentyl-[1,1'-bi(cyclohexane)]-4-carboxylate (FPeBC) were frequently detected in dust samples. We investigated potential sources of LCMs in dust by determining concentrations and profiles of these chemicals in smartphone screens, desktop and laptop computer monitors, and displays of other electronic devices and found that profiles in smartphones matched closely with those found in dust. The calculated median daily intake of ∑LCM through dust ingestion was 1.19 ng/kg bw/d for children, whereas that through dermal absorption was 0.18 ng/kg bw/d for adults in the United States.


Assuntos
Poluição do Ar em Ambientes Fechados , Poeira , Cristais Líquidos , Poeira/análise , Poluição do Ar em Ambientes Fechados/análise , Estados Unidos , Monitoramento Ambiental , Humanos
5.
Environ Sci Technol ; 58(23): 10185-10194, 2024 Jun 11.
Artigo em Inglês | MEDLINE | ID: mdl-38804824

RESUMO

The relaxation of restrictions on Chinese Spring Festival (SF) firework displays in certain regions has raised concerns due to intensive emissions exacerbating air quality deterioration. To evaluate the impacts of fireworks on air quality, a comparative investigation was conducted in a city between 2022 (restricted fireworks) and 2023 SF (unrestricted), utilizing high time-resolution field observations of particle chemical components and air quality model simulations. We observed two severe PM2.5 pollution episodes primarily triggered by firework emissions and exacerbated by static meteorology (contributing approximately 30%) during 2023 SF, contrasting with its absence in 2022. During firework displays, freshly emitted particles containing more primary inorganics (such as chloride and metals like Al, Mg, and Ba), elemental carbon, and organic compounds (including polycyclic aromatic hydrocarbons) were predominant; subsequently, aged particles with more secondary components became prevalent and continued to worsen air quality. The primary emissions from fireworks constituted 54% of the observed high PM2.5 during the displays, contributing a peak hourly PM2.5 concentration of 188 µg/m3 and representing over 70% of the ambient PM2.5. This study underscores that caution should be exercised when igniting substantial fireworks under stable meteorological conditions, considering both the primary and potential secondary effects.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Material Particulado , Material Particulado/análise , Poluentes Atmosféricos/análise , Monitoramento Ambiental , Férias e Feriados , Hidrocarbonetos Policíclicos Aromáticos/análise
6.
Nicotine Tob Res ; 2024 May 02.
Artigo em Inglês | MEDLINE | ID: mdl-38695345

RESUMO

INTRODUCTION: Addressing cigarette and e-cigarette use in China is key to reducing the global tobacco epidemic. Marketing exposure is one causal factor for adolescent smoking and e-cigarette use. Currently, China restricts cigarette and e-cigarette ads in public places and online; however, there may not be full policy compliance. We collected real-time data in the natural environment to estimate how much and where Chinese adolescents - a group susceptible to smoking and e-cigarette use - are exposed to cigarette and e-cigarette marketing to inform policy responses. METHODS: In June 2022, we conducted a seven-day ecological momentary assessment (EMA) study with 15-16-year-olds (n=96) across eight Chinese cities. Participants completed up to 42 EMA surveys (6 per day), sent at random intervals outside of school hours. In each survey, participants reported whether they saw (1) displays and (2) ads in the past hour (none, cigarette, e-cigarette, both) in the past hour. We also captured the source of cigarette/e-cigarette ad exposure. RESULTS: Most participants were exposed to cigarette and/or e-cigarette displays (89.6%) or ads (79.2%) over the seven days. On average, participants reported past-hour exposure to displays 12.7 times and past-hour exposure to ads 10.8 times over the week. The most common sources of cigarette ads were public places (e.g., kiosks, supermarkets); the most common sources of e-cigarette ad exposure were social media/internet or e-cigarette stores. CONCLUSIONS: Findings highlight the need to enhance enforcement of restrictions on cigarette and e-cigarette ads in public places and online in China and extend restrictions to ban displays. IMPLICATIONS: Marketing exposure is a causal factor in youth smoking and e-cigarette use. We used ecological momentary assessments to estimate cigarette and e-cigarette display and ad exposure among Chinese adolescents. On average, participants reported past-hour exposure to cigarette and/or e-cigarette displays 13 times and past-hour exposure to cigarette and/or e-cigarette ads 11 times over one week. Most saw ads in public places and online. Results suggest strengthening implementation of China's ban on cigarette and e-cigarette ads in public places and online and banning product displays. These are policy responses that can contribute to reducing adolescent cigarette and e-cigarette uptake in China.

7.
Artigo em Inglês | MEDLINE | ID: mdl-38598135

RESUMO

Adaptive teacher support fosters effective learning in one-to-one teaching sessions, which are a common way of learning complex visual tasks in the health sciences. Adaptive support is tailored to student needs, and this is difficult in complex visual tasks as visual problem-solving processes are covert and thus cannot be directly observed by the teacher. Eye-tracking apparatus can measure covert processes and make them visible in gaze displays: visualizations of where a student looks while executing a task. We investigate whether live dynamic gaze displays help teachers in being more adaptive to students' needs when teaching optical coherence tomography interpretation in one-to-one teaching sessions and whether this fosters learning. Forty-nine students and 10 teachers participated in a one-to-one teaching session in clinical optometry. In the control condition, teachers saw the learning task of the student and could discuss it with them, whereas in the gaze-display condition, teachers could additionally see where the student looked. After the 15-minute teaching session, a test was administered to examine achievement. Furthermore, students filled in the 'questionnaire on teacher support adaptivity', and teachers rated how adaptive their support was. Bayesian analyses provide some initial evidence that students did not experience support to be more adaptive in the gaze-display condition versus the control condition, nor were their post-test scores higher. Teachers rated their provided support as being more adaptive in the gaze-display versus the control condition. Further research could investigate if live dynamic gaze displays impact adaptive teaching when used over longer periods or with more teacher training.

8.
Ophthalmic Physiol Opt ; 44(5): 840-853, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38757445

RESUMO

PURPOSE: To compare the objective performance, acceptance and usability of head-mounted displays (HMDs) to provide evidence-based data that could be used to increase the efficiency of device referrals based upon a person's vision loss and functional needs. METHODS: A cross-sectional, counterbalanced, individually controlled crossover study was performed on 15 adults with various eye conditions. Performance was measured when using four HMDs: eSight4, Eyedaptic EYE3, Eyedaptic EYE4 and IrisVision Inspire. Performance on clinical visual acuity tests and contrast were assessed, as well as vision-related activities of daily living (ADL) which were divided into three categories: Reading, Searching & Identifying and Eye-hand Coordination. User-experience was also assessed. Logistic regression analyses, Friedman one-way repeated measure analyses of variance by ranks and multivariate permutation testing were used for analysis. RESULTS: There was a significant improvement in visual acuity when using all devices. For contrast tasks, only the eSight4 and Eyedaptic EYE3 improved performance relative to baseline. For most Reading and Searching & Identifying tasks, the odds of being able to perform the tasks were significantly higher while using the devices. However, the actual performance with most devices (e.g., number of words read or reading speed) did not improve significantly over baseline for most tasks. For the Eye-hand Coordination tasks, participants performed equivalent to or significantly poorer than baseline when using the devices. No demographic or clinical predictors of outcomes were identified. Participants expressed dissatisfaction with the devices' effectiveness, acceptability and usability. CONCLUSIONS: While performance on clinical tests was better when using the devices, performance on most real-world ADLs was equal to or worse than baseline. No single device improved performance on all tasks, and performance on any one task was not improved with all the devices. The overall dissatisfaction with the devices paralleled the lack of objective improvement in the performance of real-world tasks.


Assuntos
Atividades Cotidianas , Estudos Cross-Over , Acuidade Visual , Humanos , Masculino , Feminino , Acuidade Visual/fisiologia , Pessoa de Meia-Idade , Estudos Transversais , Adulto , Idoso , Baixa Visão/fisiopatologia , Baixa Visão/reabilitação , Pessoas com Deficiência Visual/reabilitação , Transtornos da Visão/fisiopatologia , Leitura
9.
Proc Natl Acad Sci U S A ; 118(18)2021 May 04.
Artigo em Inglês | MEDLINE | ID: mdl-33903240

RESUMO

Inorganic semiconductor-based microscale light-emitting diodes (micro-LEDs) have been widely considered the key solution to next-generation, ubiquitous lighting and display systems, with their efficiency, brightness, contrast, stability, and dynamic response superior to liquid crystal or organic-based counterparts. However, the reduction of micro-LED sizes leads to the deteriorated device performance and increased difficulties in manufacturing. Here, we report a tandem device scheme based on stacked red, green, and blue (RGB) micro-LEDs, for the realization of full-color lighting and displays. Thin-film micro-LEDs (size ∼100 µm, thickness ∼5 µm) based on III-V compound semiconductors are vertically assembled via epitaxial liftoff and transfer printing. A thin-film dielectric-based optical filter serves as a wavelength-selective interface for performance enhancement. Furthermore, we prototype arrays of tandem RGB micro-LEDs and demonstrate display capabilities. These materials and device strategies provide a viable path to advanced lighting and display systems.

10.
Proc Natl Acad Sci U S A ; 118(23)2021 06 08.
Artigo em Inglês | MEDLINE | ID: mdl-34074793

RESUMO

Liquid crystal displays (LCDs) have profoundly shaped the lifestyle of humans. However, despite extensive use, their impacts on indoor air quality are unknown. Here, we perform flow cell experiments on three different LCDs, including a new computer monitor, a used laptop, and a new television, to investigate whether their screens can emit air constituents. We found that more than 30 volatile organic compounds (VOCs) were emitted from LCD screens, with a total screen area-normalized emission rate of up to (8.25 ± 0.90) × 109 molecules ⋅ s-1 ⋅ cm-2 In addition to VOCs, 10 liquid crystal monomers (LCMs), a commercial chemical widely used in LCDs, were also observed to be released from those LCD screens. The structural identification of VOCs is based on a "building block" hypothesis (i.e., the screen-emitted VOCs originate from the "building block chemicals" used in the manufacturing of liquid crystals), which are the key components of LCD screens. The identification of LCMs is based upon the detailed information of 362 currently produced LCMs. The emission rates of VOCs and LCMs increased by up to a factor of 9, with an increase of indoor air humidity from 23 to 58% due to water-organic interactions likely facilitating the diffusion rates of organics. These findings indicate that LCD screens are a potentially important source for indoor VOCs that has not been considered previously.


Assuntos
Poluentes Atmosféricos/química , Cristais Líquidos/química , Compostos Orgânicos Voláteis/química , Poluição do Ar em Ambientes Fechados
11.
Nano Lett ; 23(2): 437-443, 2023 Jan 25.
Artigo em Inglês | MEDLINE | ID: mdl-36630612

RESUMO

Thanks to the narrow line width and high brightness, colloidal quantum dot (CQD) lasers show promising applications in next-generation displays. However, CQD laser-based displays have yet to be demonstrated because of two challenges in integrating red, green, and blue (RGB) lasers: absorption from red CQDs deteriorates the optical gain of blue and green CQDs, and imbalanced white spectra lack blue lasing due to the high lasing threshold of blue CQDs. Herein, we introduce a facile surfactant-free self-assembly method to assemble RGB CQDs into high-quality whispering-gallery-mode (WGM) RGB lasers with close lasing thresholds among them. Moreover, these RGB lasers can lase nearly independently even when they are closely integrated, and they can construct an ultrawide color space whose color gamut is 105% of that of the BT.2020 standard. These combined strategies allow us to demonstrate the first full-color liquid crystal displays using CQD lasers as the backlight source.

12.
Nano Lett ; 23(7): 3014-3022, 2023 Apr 12.
Artigo em Inglês | MEDLINE | ID: mdl-36939681

RESUMO

Herein, we demonstrate video-rate color three-dimensional (3D) volumetric displays using elemental-migration-assisted full-color-tunable upconversion nanoparticles (UCNPs). In the heavily doped NaErF4:Tm-based core@multishell UCNPs, erbium migration was observed. By tailoring this migration through adjustment of the intermediate shell thickness between the core and the sensitizer-doped second shell, red-green orthogonal upconversion luminescence (UCL) was achieved. Furthermore, highly efficient red-green-blue orthogonal UCL and full-color tunability were achieved in the UCNPs through a combination of elemental-migration-assisted color tuning and selective photon blocking. Finally, 3D volumetric displays were fabricated using a UCNP-polydimethylsiloxane composite. More specifically, 3D color images were created and motion pictures based on the expansion, rotation, and up/down movement of the displayed images were realized in the display matrix. Overall, our study provides new insights into upconversion color tuning and the achievement of motion pictures in the UCNP-polydimethylsiloxane composite is expected to accelerate the further development of solid-state full-color 3D volumetric displays.

13.
Molecules ; 29(12)2024 Jun 13.
Artigo em Inglês | MEDLINE | ID: mdl-38930893

RESUMO

The growing demand for wearable and attachable displays has sparked significant interest in flexible quantum-dot light-emitting diodes (QLEDs). However, the challenges of fabricating and operating QLEDs on flexible substrates persist due to the lack of stable and low-temperature processable charge-injection/-transporting layers with aligned energy levels. In this study, we utilized NiOx nanoparticles that are compatible with flexible substrates as a hole-injection layer (HIL). To enhance the work function of the NiOx HIL, we introduced a self-assembled dipole modifier called 4-(trifluoromethyl)benzoic acid (4-CF3-BA) onto the surface of the NiOx nanoparticles. The incorporation of the dipole molecules through adsorption treatment has significantly changed the wettability and electronic characteristics of NiOx nanoparticles, resulting in the formation of NiO(OH) at the interface and a shift in vacuum level. The alteration of surface electronic states of the NiOx nanoparticles not only improves the carrier balance by reducing the hole injection barrier but also prevents exciton quenching by passivating defects in the film. Consequently, the NiOx-based red QLEDs with interfacial modification demonstrate a maximum current efficiency of 16.1 cd/A and a peak external quantum efficiency of 10.3%. This represents a nearly twofold efficiency enhancement compared to control devices. The mild fabrication requirements and low annealing temperatures suggest potential applications of dipole molecule-modified NiOx nanoparticles in flexible optoelectronic devices.

14.
Scand J Psychol ; 2024 Jun 14.
Artigo em Inglês | MEDLINE | ID: mdl-38877602

RESUMO

The present study investigated the effects of expansive and contractive body displays on adaptive behavior and affective outcomes. Addressing limitations in past research, the effects were investigated in two different contexts (i.e., fear context and sadness context), compared with two types of control conditions and the moderating effects of motivational traits and symptoms of psychopathology were accounted for. A sample of 186 adults completed a fear experiment involving a mock job interview and a sadness experiment involving sad mood induction. For each experiment, participants were randomly assigned to one of four body manipulations: (1) expansive; (2) contractive; (3) active control (i.e., running in place); or 4) passive control (i.e., doing nothing). The primary outcome was adaptive behavior (i.e., appropriate job-interview behavior and positive recall bias). Secondary affective outcomes were emotions, action tendencies, and appraisals. Results revealed small, non-significant effects of body displays on primary outcomes (ds = 0.19-0.28). For secondary outcomes, significant effects were identified for positive emotions (ds = 0.33). Across secondary outcomes, pairwise comparisons revealed that expansive displays led to more favorable outcomes than contractive displays. For participants with the highest levels of depression, body display conditions led to less favorable affective outcomes than control conditions. The results suggest that body displays do not influence adaptive behavior within the investigated contexts. When compared to contractive displays, expansive displays were found to yield more favorable affective changes. Lastly, the findings indicate that further investigations into body manipulations in the context of psychopathology are warranted.

15.
Ergonomics ; : 1-10, 2024 Apr 13.
Artigo em Inglês | MEDLINE | ID: mdl-38613402

RESUMO

Head-up displays (HUDs) have the potential to change work in operation environments by providing hands-free information to wearers. However, these benefits may be accompanied by trade-offs, primarily by increasing cognitive load due to dividing attention. Previous studies have attempted to understand the trade-offs of HUD usage; however, all of which were focused on land-based tasks. A gap in understanding exists when examining HUD use in aquatic environments as immersion introduces unique environmental and physiological factors that could affect multitasking. In this study, we investigated multitasking performance associated with swimming with a HUD. Eighteen participants completed three tasks: swimming only, a HUD-administered word recall task, and a dual-task combining both tasks. Results revealed significant dual-task interference in both tasks, though possibly less pronounced than in land-based tasks. These findings enhance not only help characterise dual-task performance, but also offer valuable insights for HUD design for aquatic settings.


HUDs have become an increasingly popular tool to present information to users in complex working environments. However, past research examining HUD task performance has been restricted to land-based contexts. The current study examines HUD use while swimming and provides characterisation of multitasking performance within aquatic environments.

16.
J Relig Health ; 63(1): 788-816, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38227155

RESUMO

This study explores the dynamics of coping strategies of Czech religious leaders during a peak of the COVID-19 pandemic. An interpretative phenomenological analysis reveals that mental health among pastors is closely linked to a need to maintain community and social contact, while physical health is related to limitations upon ritual elements. In all narratives, the lived experience of mental health in the form of prosocial behavior is significantly prioritized despite the possibility of spreading infection. The analysis also shows that maintaining the community is closely linked to risky behaviors, which positively affected group and individual well-being.


Assuntos
COVID-19 , Canto , Humanos , Clero , República Tcheca/epidemiologia , Pandemias
17.
Neuroimage ; 270: 119909, 2023 04 15.
Artigo em Inglês | MEDLINE | ID: mdl-36801370

RESUMO

Accurate motion perception requires that the visual system integrate the 2D retinal motion signals received by the two eyes into a single representation of 3D motion. However, most experimental paradigms present the same stimulus to the two eyes, signaling motion limited to a 2D fronto-parallel plane. Such paradigms are unable to dissociate the representation of 3D head-centric motion signals (i.e., 3D object motion relative to the observer) from the associated 2D retinal motion signals. Here, we used stereoscopic displays to present separate motion signals to the two eyes and examined their representation in visual cortex using fMRI. Specifically, we presented random-dot motion stimuli that specified various 3D head-centric motion directions. We also presented control stimuli, which matched the motion energy of the retinal signals, but were inconsistent with any 3D motion direction. We decoded motion direction from BOLD activity using a probabilistic decoding algorithm. We found that 3D motion direction signals can be reliably decoded in three major clusters in the human visual system. Critically, in early visual cortex (V1-V3), we found no significant difference in decoding performance between stimuli specifying 3D motion directions and the control stimuli, suggesting that these areas represent the 2D retinal motion signals, rather than 3D head-centric motion itself. In voxels in and surrounding hMT and IPS0 however, decoding performance was consistently superior for stimuli that specified 3D motion directions compared to control stimuli. Our results reveal the parts of the visual processing hierarchy that are critical for the transformation of retinal into 3D head-centric motion signals and suggest a role for IPS0 in their representation, in addition to its sensitivity to 3D object structure and static depth.


Assuntos
Percepção de Movimento , Córtex Visual , Humanos , Retina/diagnóstico por imagem , Percepção Visual , Córtex Visual/diagnóstico por imagem , Movimento (Física) , Estimulação Luminosa
18.
Small ; : e2307216, 2023 Dec 11.
Artigo em Inglês | MEDLINE | ID: mdl-38078782

RESUMO

Phosphors with narrow-band green emissions and high photoluminescent quantum efficiency (PLQY) are significantly required for backlighting displays with wider color gamut. In this work, two centimeter-sized manganese (II) halide single crystals TMG2 MnCl4 and TMG2 MnBr4 (TMG = 1,1,3,3-tetramethylguanidine) are synthesized, exhibiting bright narrow-band green emissions with high PLQYs up to 62% and 90%, respectively. The narrow-band green light emission is located at 520 nm with a full-width at half-maximum (FWHM) of only 57 nm. The photoluminescence mechanisms of two single crystals are elaborated. Two white-light-emitting diodes for backlighting displays (BD-WLEDs) based on them are fabricated, exhibiting the widest color gamut of 122% National Television Standards Committee (NTSC), and a luminous efficacy reached ≈93 lm W-1 with excellent luminescence stability at high temperatures. These properties indicate the potential applications of tetrahedral manganese (II) hybrids in wide-color gamut backlighting displays.

19.
Small ; 19(39): e2302241, 2023 09.
Artigo em Inglês | MEDLINE | ID: mdl-37260144

RESUMO

Precisely delivering light to multiple locations in biological tissue is crucial for advancing multiregional optogenetics in neuroscience research. However, conventional implantable devices typically have rigid geometries and limited light sources, allowing only single or dual probe placement with fixed spacing. Here, a fully flexible optogenetic device with multiple thin-film microscale light-emitting diode (µ-LED) displays scattering from a central controller is presented. Each display is heterogeneously integrated with thin-film 5 × 10 µ-LEDs and five optical fibers 125 µm in diameter to achieve cellular-scale spatial resolution. Meanwhile, the device boasts a compact, flexible circuit capable of multichannel configuration and wireless transmission, with an overall weight of 1.31 g, enabling wireless, real-time neuromodulation of freely moving rats. Characterization results and finite element analysis have demonstrated excellent optical properties and mechanical stability, while cytotoxicity tests further ensure the biocompatibility of the device for implantable applications. Behavior studies under optogenetic modulation indicate great promise for wirelessly modulating neural functions in freely moving animals. The device with multisite and multiregional optogenetic modulation capability offers a comprehensive platform to advance both fundamental neuroscience studies and potential applications in brain-computer interfaces.


Assuntos
Optogenética , Próteses e Implantes , Ratos , Animais , Optogenética/métodos , Fibras Ópticas , Tecnologia sem Fio , Córtex Cerebral
20.
Chemistry ; 29(61): e202301746, 2023 Nov 02.
Artigo em Inglês | MEDLINE | ID: mdl-37706626

RESUMO

The three-dimensional arrangement of atoms in molecules is essential for understanding their properties and behavior. Traditional 2D representations and digital 3D models presented on 2D media often fall short in conveying the complexity of molecular structures. Autostereoscopic displays, often marketed as "holographic" displays, pose a potential solution to this challenge. These displays, with their multi-view and single-view configurations, promise to advance chemistry education and research by offering accurate 3D representations with depth and parallax. In this perspective, I delve into the possibilities and limitations of autostereoscopic displays in chemistry, discussing the underlying technology and potential applications, from research to teaching and science communication. Multi-view autostereoscopic displays excel in facilitating collaborative work by enabling multiple viewers to simultaneously perceive the same 3D structure from different angles. However, they currently suffer from low resolution and high cost, which could limit their immediate widespread adoption. Conversely, single-view autostereoscopic displays with eye-tracking, while limited to one viewer at a time, provide higher resolution at a lower cost, thus suggesting that they might become the technology of the future given the balance of price to performance. Despite current limitations, autostereoscopic displays possess undeniable potential for shaping the future of chemistry education and research.

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