An amino-rich polymer-coated magnetic nanomaterial for ultra-rapid separation of phosphorylated peptides in the serum of Parkinson's disease patients.

The elucidation of disease pathogenesis can be achieved by analyzing the low-abundance phosphopeptides in organisms. Herein, we developed a novel and easy-to-prepare polymer-coated nanomaterial. By improving the hydrophilicity and spatial conformation of the material, we effectively enhanced the adsorption of phosphopeptides and demonstrated excellent enrichment properties. The material was able to successfully enrich the phosphopeptides in only 1 min. Meanwhile, the material has high selectivity (1:2000), good loading capacity (100 µg/mg), excellent sensitivity (0.5 fmol), and great acid and alkali resistance. In addition, the material was applied to real samples, and 70 phosphopeptides were enriched from the serum of Parkinson's disease (PD) patients and 67 phosphopeptides were enriched from the serum of normal controls. Sequences Logo showed that PD is probably associated with threonine, glutamate, serine, and glutamine. Finally, gene ontology (GO) analysis was performed on phosphopeptides enriched in PD patients' serum. The results showed that PD patients expressed abnormal expression of the cholesterol metabolic process and cell-matrix adhesion in the biological process (BP), endoplasmic reticulum and lipoprotein in the cellular component (CC), and heparin-binding, lipid-binding, and receptor-binding in the molecular function (MF) as compared with normal individuals. All the experiments indicate that the nanomaterials have great potential in proteomics studies.

Applications of magnetic solid-phase extraction in the sample preparation of natural product analysis (2020-2023).

Sample preparation, including extraction, separation, and purification, is a vital process for natural product analysis. As an attractive sample pretreatment method, magnetic solid-phase extraction (MSPE) has gained plenty of attention, mainly due to its simpler operation, less consumption of organic solvents, and shorter processing time than traditional SPE. This updated review is devoted to summarizing the applications of MSPE based on different magnetic nanomaterials in the analysis of various natural products in complex matrixes, such as biological samples, plants, and Chinese herbal preparations in the past four years (2020-2023). The preparation and fabrication of different materials are briefly introduced. Furthermore, the extraction mechanism and interaction forces between adsorbent and analytes are elaborated, and the advantages and disadvantages of different adsorbents coupled with various analytical methods for MSPE of different natural products are summarized. Moreover, the future trends and opportunities for MSPE in the natural product analysis are discussed. It is expected that this work can provide updated information for future research on the applications of MSPE in such fields.

Synthesis of biochar-CoFe2O4 nanocomposite for adsorption of methylparaben from wastewater under full factorial experimental design.

The presence of endocrine-disrupting chemicals in municipal wastewater has emerged as a threat to human health and the environment. Therefore, this study aimed to develop biochar-cobalt ferrite (BCF) nanocomposite for the removal of methylparaben from water under the full factorial experimental design of 4 factors with 3 levels (34). The biochar-CoFe2O4 nanocomposite was developed by co-precipitation method from cobalt ferrite and biochar of Eucalyptus tree bark. Adsorbent surface morphology and functional and elemental composition were carried out by scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, and energy-dispersive X-ray spectroscopy (EDS) techniques which showed the presence of cracks with a rough surface, reasonable surface chemical composition, and many chemical functional groups, respectively. The experimental and predicted adsorption efficiencies ranged from 25.3 to 85.6% and 21.8 to 80.3%, respectively. The maximum adsorption performance (85.6%) reduced the methylparaben concentration from 27.5 to 4.0 mg/L at the optimum condition of adsorbent dose of 55 mg/100 mL, pH 6, contact time 90 min, and the initial methylparaben concentration of 27.5 mg/L. However, the adsorbent dose was the most influential main factor whereas the least influential was the interaction between solution pH and contact time under the regression model. The model also showed that 69% methylparaben removal was described by the regression model. The experimental data best fitted with the Freundlich model indicate multilayer adsorption which is the implication of physisorption. The sorption mechanism is attributed to Vander Waals forces, H-bonding, and dipole interaction. This BCF nanocomposite adsorbent appears to be promising for the removal of methylparaben from wastewater, but a further optimization process is essential to boost the treatment performance.

Current Applications of Magnetic Nanomaterials for Extraction of Mycotoxins, Pesticides, and Pharmaceuticals in Food Commodities.

Environmental pollutants, such as mycotoxins, pesticides, and pharmaceuticals, are a group of contaminates that occur naturally, while others are produced from anthropogenic sources. With increased research on the adverse ecological and human health effects of these pollutants, there is an increasing need to regularly monitor their levels in food and the environment in order to ensure food safety and public health. The application of magnetic nanomaterials in the analyses of these pollutants could be promising and offers numerous advantages relative to conventional techniques. Due to their ability for the selective adsorption, and ease of separation as a result of magnetic susceptibility, surface modification, stability, cost-effectiveness, availability, and biodegradability, these unique magnetic nanomaterials exhibit great achievement in the improvement of the extraction of different analytes in food. On the other hand, conventional methods involve longer extraction procedures and utilize large quantities of environmentally unfriendly organic solvents. This review centers its attention on current applications of magnetic nanomaterials and their modifications in the extraction of pollutants in food commodities.

Electrochemical thrombin aptasensor based on using magnetic nanoparticles and porous carbon prepared by carbonization of a zinc(II)-2-methylimidazole metal-organic framework.

A homogeneous electrochemical aptasensor was obtained by modifying a glassy carbon electrode (GCE) with a porous carbon nanomaterial (Z-1000, about 70 nm, deteced by transmission electron microscopic) that was obtained by carbonization of a zinc(II)-2-methylimidazole metal-organic framework. Z-1000 possesses a large specific surface and outstanding electrochemical properties. A thrombin-binding aptamer (CP) was immobilized on the magnetite nanoparticles MNPs by the condensation reaction and further combined with reporter probe (RP) that is functionalized with electroactive methylene blue (MB). In the presence of thrombin, the CP was specifically recognized with it to form the CP/MNP/Thb complex, and the RP was dissociated from MNPs. The released RP was captured by the modified GCE through π-stacking interaction between nucleobases and carbon nanostructure. The electrical signal generated by MB can be monitored by differential pulse voltammetry (DPV). Under the optimized conditions, the DPV peak current at around -0.28 V (vs. SCE) increases with thrombin concentration. The sensor has a detection limit of 0.8 fM of thrombin and a linear range that extends from 10 fM to 100 nM. It was successfully applied to the analysis of spiked serum. The recoveries are 98.1-99.4% and RSDs are 3.9%-4.0%. Conceivably, this aptasensor scheme can be easily extended to other proteins and gives inspiration to manufacture sensitive aptasensor. Graphical abstract A homogeneous electrochemical aptasensor is obtained by modifying a glassy carbon electrode with the MOF-derived porous carbon. The sensor has a detection limit of 0.8 fM and a wide linear range from 10 fM to 100 nM for thrombin detection.

Electromagnetic Field Drives the Bioelectrocatalysis of γ-Fe2O3-Coated Shewanella putrefaciens CN32 to Boost Extracellular Electron Transfer.

The microbial hybrid system modified by magnetic nanomaterials can enhance the interfacial electron transfer and energy conversion under the stimulation of a magnetic field. However, the bioelectrocatalytic performance of a hybrid system still needs to be improved, and the mechanism of magnetic field-induced bioelectrocatalytic enhancements is still unclear. In this work, γ-Fe2O3 magnetic nanoparticles were coated on a Shewanella putrefaciens CN32 cell surface and followed by placing in an electromagnetic field. The results showed that the electromagnetic field can greatly boost the extracellular electron transfer, and the oxidation peak current of CN32@γ-Fe2O3 increased to 2.24 times under an electromagnetic field. The enhancement mechanism is mainly due to the fact that the surface modified microorganism provides an elevated contact area for the high microbial catalytic activity of the outer cell membrane's cytochrome, while the magnetic nanoparticles provide a networked interface between the cytoplasm and the outer membrane for boosting the fast multidimensional electron transport path in the magnetic field. This work sheds fresh scientific light on the rational design of magnetic-field-coupled electroactive microorganisms and the fundamentals of an optimal interfacial structure for a fast electron transfer process toward an efficient bioenergy conversion.

Magnetically Controlled Nanorobots Based on Red Emissive Peptide Dots and Artificial Antibodies for Specific Recognition and Smart Scavenging of Nε-(Carboxymethyl)lysine in Dairy Products.

Food-borne advanced glycation end products (AGEs) are highly related to various irreversible diseases, and Nε-(carboxymethyl)lysine (CML) is the typical hazardous AGE. The development of feasible strategies to monitor and reduce CML exposure has become desirable to address the problems. In this work, we proposed magnetically controlled nanorobots by integrating an optosensing platform with specific recognition and binding capability, realizing specific anchoring and accurate determination as well as efficient scavenging of CML in dairy products. The artificial antibodies offered CML imprinted cavities for highly selective absorption, and the optosensing strategy was designed based on electron transfer from red emissive self-assembling peptide dots (r-SAPDs) to CML, which was responsible for the identity, response, and loading process. The r-SAPDs overcame the interference from autofluorescence, and the limit of detection was 0.29 µg L-1, which bestowed accuracy and reliability for in situ monitoring. The selective binding process was accomplished within 20 min with an adsorption capacity of 23.2 mg g-1. Through an external magnetic field, CML-loaded nanorobots were oriented, moved, and separated from the matrix, which enabled their scavenging effects and reusability. The fast stimuli-responsive performance and recyclability of the nanorobots provided a versatility strategy for effective detection and control of hazards in food.

Fabrication of poly-dopamine-modified magnetic nanomaterial and development of integrated QuEChERS method for 122 pesticides residue analysis in fruits.

A rapid and accurate integrated QuEChERS method was established for the determination of multi-pesticide residues in fruits. Poly-dopamine-modified magnetic nanomaterial (Fe3O4-pDA) was homemade and characterized. The prepared Fe3O4-pDA has the functional group of absorbing the saccharides, and can be used as co-adsorbent with 3-(N, n­diethyl amino) propyl trimethoxy-silane (PSA) in the developed integrated QuEChERS method to purify the fruit matrix, thus achieve the accurate determination of multi-pesticides residue. Grape was used as the representative sample to explore the influence of the salting out agent and each purification adsorbent on the pesticide recoveries. Under the optimized conditions, the proposed method showed good linearity for 92.6% of pesticides in the concentration range of 1-150 µg L-1 with method limit of quantitative (mLOQs) ranged from 10 to 18 µg kg-1. Spiked recoveries experiments were performed on four kinds of grapes and other fruits (apple, watermelon, pear, jujube and peach), in which satisfactory recoveries and precision were obtained for most of the pesticides. Meanwhile, comparison experiments also verified this method was superior to the traditional QuEChERS method in terms of convenient operation, high efficiency and low reagent consumption. The further real sample analysis was performed using this method, and the overall detection rate was 52%, while 2% of samples were exceeding the maximum residue limits. All results confirmed that the proposed method could be used for the rapid, simple, low-costing and effective analyses of trace multi-pesticides residue in fruit samples.

An Ultrathin Tunable Metamaterial Absorber for Lower Microwave Band Based on Magnetic Nanomaterial.

At frequencies below 1 GHz, conventional microwave absorbers are limited by their large thickness or narrow absorption bandwidth; therefore, new techniques for efficient absorption for the lower microwave band are highly demanded. Here, we propose and fabricate an ultrathin tunable metamaterial absorber combining magnetic nanomaterials and metamaterial resonant structures for use in the lower microwave band (P band). The proposed absorber utilizes electrically controlled varactors to enable frequency tunability and magnetic nanomaterials as dielectric slabs for thickness reduction and bandwidth expansion at low frequencies. By adjusting the bias voltages of varactors, the resonant behavior of the absorbing structure can be dynamically tuned that covers a continuously tunable absorbing band from 0.41 to 1.02 GHz (85.3% in fractional bandwidth) with at least 10 dB reflection reduction. The total thickness of this absorber is 5 mm, which is only about 1/146 the wavelength of the lowest frequency. The agreement between the simulated and measured results validates the proposed design, and the structure has good angular stability that may be used as complex targets for low-RCS applications.

Photonic and magnetic materials for on-demand local drug delivery.

Nanomedicine has been considered a promising tool for biomedical research and clinical practice in the 21st century because of the great impact nanomaterials could have on human health. The generation of new smart nanomaterials, which enable time- and space-controlled drug delivery, improve the limitations of conventional treatments, such as non-specific targeting, poor biodistribution and permeability. These smart nanomaterials can respond to internal biological stimuli (pH, enzyme expression and redox potential) and/or external stimuli (such as temperature, ultrasound, magnetic field and light) to further the precision of therapies. To this end, photonic and magnetic nanoparticles, such as gold, silver and iron oxide, have been used to increase sensitivity and responsiveness to external stimuli. In this review, we aim to report the main and most recent systems that involve photonic or magnetic nanomaterials for external stimulus-responsive drug release. The uniqueness of this review lies in highlighting the versatility of integrating these materials within different carriers. This leads to enhanced performance in terms of in vitro and in vivo efficacy, stability and toxicity. We also point out the current regulatory challenges for the translation of these systems from the bench to the bedside, as well as the yet unresolved matter regarding the standardization of these materials.

Ionic liquid-based magnetic nanoparticles for magnetic dispersive solid-phase extraction: A review.

Due to their highly tunable nature and outstanding physicochemical properties, ionic liquids (ILs) have been widely reported for use in the synthesis of multitudinous magnetic nanoparticles (MNPs). IL-based magnetic nanoparticles (IL-MNPs) have great potential in magnetic dispersive solid-phase extraction (MDSPE). At present, IL-MNPs have been successfully applied in the pretreatment of MDSPE samples from medicines, pesticides, veterinary drugs, heavy metals, dyes, additives, and proteins in agricultural products, foods and beverages, environmental water, and biological samples. In this review, the preparation of IL-MNPs and their application in MDSPE are comprehensively summarized. The structural characteristics of the introduced ILs used to prepare the IL-MNPs and the synthetic routes employed to obtain the IL-MNPs are described, including physical coating and chemical bonding methods. The IL-MNPs are then classified and described according to different modified materials, including silica-based materials, carbon-based materials, metal-organic frameworks, molecularly imprinted polymers and other interesting large/small molecules. Finally, the research prospects and development directions of IL-MNPs in the context of MDSPE are further identified.

Simultaneous adsorption of mercury species from aquatic environments using magnetic nanoparticles coated with nanomeric silver functionalized with l-Cysteine.

We introduce a novel, efficient and fast method for the total and simultaneous removal of monomethylmercury, dimethylmercury, ethylmercury and Hg (II) from aquatic environments using magnetic core nanoparticles, coated with metallic nanomeric silver and functionalized with l-Cysteine. As far as the authors know, simultaneous removal has not been achieved previously. The experimental design was based on exploring a wide range of experimental conditions, including pH of the medium (2-12), contact time (up to 20 min), adsorbent dose (50-800 µL) and temperature (293-323 K), in order to achieve the highest adsorption efficiency. The results show that, for a pH equal to 6.2 at room temperature, 400 µL of nanoparticles is sufficient to achieve 100% adsorption efficiency for all the studied Hg species after a contact time of 30 s. The adsorbent was characterized by means of Scanning Electron Microscopy, Energy Dispersive X-ray Analysis, Fourier-Transform Infrared Spectroscopy and a BET test. Moreover, the procedure allows the total recovery and recycling of the nanoparticles using 50 µL of 0.01 M KI. As regards reuse, the adsorbent exhibits no loss of adsorption capacity during the first three adsorption cycles. Thermodynamics reveals that adsorption is of a physicochemical nature, the equilibrium isotherms being described by a Langmuir model for all the Hg species. The ability of the method to simultaneously adsorb all species of mercury present in water, achieving full adsorption in just a few seconds, along with the simple experimental conditions and its cost-effectiveness, strongly support the approach as an alternative to current procedures.

[Effects of Superparamagnetic Nanomaterials on Soil Microorganisms and Enzymes in Cadmium-Contaminated Paddy Fields].

Using Fe3O4 and hydroxyapatite as raw materials, superparamagnetic nanometer-sized Fe3O4-phosphate functionalized materials (MFH) were prepared. Soil was subsequently magnetically repaired by adding MFH to cadmium-contaminated paddy field soil. Two kinds of rice with high (Yuzhenxiang) and low (Xiangwanxian-13) cadmium enrichment were selected for conduct pot experiments to study the effect of MFH magnetic separation on soil microorganisms and enzymes, and explore the possibility of application in the remediation of cadmium-polluted farmland. The results showed that MFH application improved the soil remediation effect, with significantly reduced total Cd (38.9%) and available Cd (27.3%) contents. In addition, the Cd content of the two kinds of rice grain was significantly reduced. After MFH magnetic separation, soil microbial community diversity and richness were decreased during the jointing, heading, and maturing stages of the two rice varieties. Treatment of cultivated Yuzhenxiang rice with high concentrations of Cd significantly increased the abundance of dominant Firmicute bacteria in the rice field during the jointing and heading stages. With the use of MFH in the magnetic separation, urease, catalase, and soil peroxidase activity were improved during the jointing, heading, and maturing stages of the two rice soils. The POD enzyme activity in the soil planted with Yuzhenxiang was slightly higher than that planted with Xiangwanxian-13, while urease activity showed the opposite trend.

Application of magnetic nanomaterials in bioanalysis.

The importance of magnetic nanomaterials and magnetic hybrid materials, which are classified as new generation materials, in analytical applications is increasingly understood, and research on the adaptation of these materials to analytical methods has gained momentum. Development of sample preparation techniques and sensor systems using magnetic nanomaterials for the analysis of inorganic, organic and biomolecules in biological samples, which are among the samples that analytical chemists work on most, are among the priority issues. Therefore in this review, we focused on the use of magnetic nanomaterials for the bioanalytical applications including inorganic and organic species and biomolecules in different biological samples such as primarily blood, serum, plasma, tissue extracts, urine and milk. We summarized recent progresses, prevailing techniques, applied formats, and future trends in sample preparation-analysis methods and sensors based on magnetic nanomaterials (Mag-NMs). First, we provided a brief introduction of magnetic nanomaterials, especially their magnetic properties that can be utilized for bioanalytical applications. Second, we discussed the synthesis of these Mag-NMs. Third, we reviewed recent advances in bioanalytical applications of the Mag-NMs in different formats. Finally, recently literature studies on the relevance of Mag-NMs for bioanalysis applications were presented.

Preparation of poly(4-vinylpyridine)-functionalized magnetic Al-MOF for the removal of naproxen from aqueous solution.

In this work, a novel poly(4-vinylpyridine)-functionalized magnetic Al-MOF (Al-MOF-Fe3O4@P4VP) was synthesized successfully as an adsorbent for the adsorption of naproxen from aqueous solution. The resulting adsorbent was characterized with scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, vibrating sample magnetometer (VSM), BET surface area and X-ray photoelectron spectroscopy (XPS). Al-MOF-Fe3O4@P4VP had high surface area (123.68 m2/g), porous structure, rough surface and magnetic property. The maximum adsorption capacity of Al-MOF-Fe3O4@P4VP for naproxen could reach up to 31.67 mg/g and the adsorption process was well described by the Freundlich isotherm. The adsorption rate of naproxen on Al-MOF-Fe3O4@P4VP was very fast and the kinetics could be well modeled by the pseudo-second-order model. The adsorbent exhibited good adsorption ability even after ten adsorption-desorption cycles. Al-MOF-Fe3O4@P4VP had the characteristics of high removal efficiency, fast adsorption speed, good reusability and easy separation, making it a novel environment-friendly and effective magnetic nanomaterial in adsorbing naproxen from wastewater.

γ-Fe2O3 magnetic nanoparticle functionalized with carboxylated multi walled carbon nanotube for magnetic solid phase extractions and determinations of Sudan dyes and Para Red in food samples.

Hybrid nanostructures composed of γ-Fe2O3 (maghemite) and carboxylated-multi walled carbon nanotube (cMWCNT) were used for the magnetic solid phase extractions and determination of Sudan I, II, III, IV, Para Red, Sudan Black B and Sudan Red 7B in chili products. High performance liquid chromatography (HPLC) was employed for the measurements. Limit of quantification (LOQ) values were found in the range 0.44-2.82ngmL-1 for analytes. The best extraction parameters were determined as pH 8.0, 40mg of magnetic nanoparticle, 4.0min of contact time, 0.3mL desorption by acetonitrile. The samples were dissolved in acetone-dichloromethane-methanol (3:2:1, v/v/v) and diluted with acetonitrile-methanol (v/v; 80:20) before the method was applied. Concentrations of Sudan dyes and Para Red were determined in four samples of chili powder from less than LOQ to 31.21±1.6ngg-1, two samples of chili tomato sauces (lower than LOQ) and two samples of ketchup (lower than LOQ).

Simultaneous determination of cadmium, lead and mercury ions at trace level by magnetic solid phase extraction with Fe@Ag@Dimercaptobenzene coupled to high performance liquid chromatography.

Pollution resulted from heavy metal ions have absorbed much attention, and it is of great importance to develop sensitive and simultaneous determination method for them with common technologies without highly sensitive instruments. We prepared a new and functional core-shell magnetic nano-material, Fe@Ag@dimercaptobenzene (Fe@Ag@DMB), by a one-step method with sodium borohydride as the reducing agent and transmission electron microscopy (TEM) and energy dispersive spectrometer (EDS) were used for characterisation. The mercapto functional groups on the newly synthesised magnetic nanoparticles could interact with Cd2+, Pb2+, and Hg2+ ions in water samples and then efficient extraction for Cd2+, Pb2+, and Hg2+ ions was achieved. DDTC-Na solution was a good elutent for elution of these ions from Fe@Ag@DMB nanoparticles. Based on these, a sensitive method was developed for simultaneous preconcentration and determination of the aforementioned ions using magnetic Fe@Ag@DMB nanoparticles as the magnetic solid phase extraction adsorbent prior to high performance liquid chromatography coupled with variable wavelength detection. Under the optimal conditions, the detection limits of the three metal ions were in the range of 0.011-0.031µgL-1, and precisions were below 2.37% (n=6). The proposed method was evaluated with real water samples, and excellent spiked recoveries achieved indicated that the developed method would be a promising tool for monitoring these heavy metal ions in water samples.

Recycling Fe and improving organic pollutant removal via in situ forming magnetic core-shell Fe3O4@CaFe-LDH in Fe(II)-catalyzed oxidative wastewater treatment.

Due to its high efficiency, Fe(II)-based catalytic oxidation has been one of the most popular types of technology for treating growing organic pollutants. A lot of chemical Fe sludge along with various refractory pollutants was concomitantly produced, which may cause secondary environmental problems without proper disposal. We here innovatively proposed an effective method of achieving zero Fe sludge, reusing Fe resources (Fe recovery = 100%) and advancing organics removal (final TOC removal > 70%) simultaneously, based on the in situ formation of magnetic Ca-Fe layered double hydroxide (Fe3O4@CaFe-LDH) nano-material. Cations (Ca2+ and Fe3+) concentration (≥ 30 mmol/L) and their molar ratio (Ca:Fe ≥ 1.75) were crucial to the success of the method. Extrinsic nano Fe3O4 was designed to be involved in the Fe(II)-catalytic wastewater treatment process, and was modified by oxidation intermediates/products (especially those with COO- structure), which promoted the co-precipitation of Ca2+ (originated from Ca(OH)2 added after oxidation process) and by-produced Fe3+ cations on its surface to in situ generate core-shell Fe3O4@CaFe-LDH. The oxidation products were further removed during Fe3O4@CaFe-LDH material formation via intercalation and adsorption. This method was applicable to many kinds of organic wastewater, such as bisphenol A, methyl orange, humics, and biogas slurry. The prepared magnetic and hierarchical CaFe-LDH nanocomposite material showed comparable application performance to the recently reported CaFe-LDHs. This work provides a new strategy for efficiently enhancing the efficiency and economy of Fe(II)-catalyzed oxidative wastewater treatment by producing high value-added LDHs materials.

Magnetic nanomaterial derived from graphene oxide/layered double hydroxide hybrid for efficient removal of methyl orange from aqueous solution.

Magnetic hybrid nanomaterials composed of reduced graphene oxide, zero-valent nickel, and NiAl-mixed metal oxides (rGO/Ni/MMO) have been synthesized by calcining graphene oxide (GO)/layered double hydroxide (LDH) hybrid in nitrogen atmosphere. Structural characterizations demonstrate that with the presence of GO substrate, NiAl-LDHs can be reduced into zero-valent Ni and NiAl-MMOs during calcination. Transmission electron microscopy (TEM) is used to investigate the morphology of the as-prepared hybrid nanomaterials, demonstrating that the introduction of GO substrate prevents the aggregation of LDHs. Magnetism characterization proves the ferromagnetic property of rGO/Ni/MMO hybrid. This magnetic hybrid nanomaterial exhibits excellent adsorption ability toward methyl orange (MO) in aqueous solutions. The kinetics of the adsorption process and the adsorption isotherm are investigated. The MO removal process is found to obey the Redlich-Peterson isotherm model, and its kinetics follows pseudo-second-order rate equation. In addition, the magnetic hybrid also exhibits good recycle ability for MO removal. This novel magnetic hybrid nanomaterial derived from GO/LDH hybrid demonstrates great potential in the applications of water treatment.