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1.
Am J Otolaryngol ; 45(2): 104185, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38104469

RESUMO

INTRODUCTION: There has been historical controversy regarding the extent of resection in the management of pleomorphic adenomas. This study aims to evaluate the extent of surgery and short-term postoperative outcomes of partial superficial parotidectomy (PSP) for the management of pleomorphic adenomas at a tertiary, high-volume center. METHODS: A retrospective chart review of patients who underwent PSP was performed. Variables included demographics, pre-operative facial nerve function, operative techniques, postoperative complications/facial nerve function, and recurrence. RESULTS: 151 adults who underwent PSP for pleomorphic adenoma from January 1st, 2000 to December 31st, 2022 were identified. Median age was 55 (IQR 40-66) years with females representing 74 % of the cohort. Median tumor size at presentation was 1.8 (IQR 1.3-2.3) cm. Baseline facial nerve function was excellent for most patients (House-Brackmann I, 99 %). Most patients underwent a superficial inferior parotidectomy (88 %). Modified Blair incision (70 %) was the most common incision. Intraoperatively, the facial nerve was identified in 149 (99 %) patients. The main trunk was identified in 126 (85 %) patients. No patient had tumor spillage. Only two patients required parotid bed reconstruction. The most common complication was ear numbness (60 %). Postoperatively, 114 patients were House-Brackmann grade I at both preoperative and postoperative assessment, 8 went from grade I to II, and 1 went from grade VI to II (Bell's palsy that resolved to grade II following surgery). Median follow-up was 1(IQR 1-5) month. CONCLUSION: PSP is efficacious in the management of pleomorphic adenomas with preservation of facial nerve function, and minimal post-operative complications. Future study is needed to assess long term recurrence risk.


Assuntos
Adenoma Pleomorfo , Neoplasias Parotídeas , Adulto , Feminino , Humanos , Pessoa de Meia-Idade , Glândula Parótida/cirurgia , Glândula Parótida/patologia , Adenoma Pleomorfo/cirurgia , Adenoma Pleomorfo/patologia , Neoplasias Parotídeas/cirurgia , Neoplasias Parotídeas/patologia , Estudos Retrospectivos , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/patologia , Recidiva Local de Neoplasia/epidemiologia , Recidiva Local de Neoplasia/patologia
2.
Am J Otolaryngol ; 45(6): 104446, 2024 Jul 31.
Artigo em Inglês | MEDLINE | ID: mdl-39096567

RESUMO

OBJECTIVES: Acinic cell carcinoma (ACC) most frequently arises in the parotid gland. Treatment consists of surgical resection and sometimes adjuvant therapy. ACC is most often a low-grade malignancy with good prognosis. Higher-grade tumors are often treated aggressively with total parotidectomy, neck dissection, and adjuvant therapy; however, the effect of parotid gland resection extent on oncologic outcomes has not been studied. Herein, we examine predictors of oncologic outcomes, including the effect of extent of resection. METHODS: Patients with diagnosis of parotid ACC treated at our institution were included in this retrospective study. Patient factors were examined, and patients were grouped by extent of resection and tumor grade. RESULTS: 58 patients, including 32 low-grade, 7 intermediate-grade, and 14 high-grade were included. Patients with low-grade tumors were more likely to undergo lesser extent of parotidectomy and less likely to undergo neck dissection. Two patients with low grade tumors developed recurrence, one local and one regional. Recurrence rate did not differ with resection extent in low-grade tumors. High tumor grade was found to be associated with disease progression. There was no association with adjuvant treatment and outcomes. Across all tumor grades advanced AJCC stage was found to be associated with disease progression. CONCLUSIONS: In ACC patients with low-grade tumors and lower disease stage who undergo lesser extent of surgical resection oncologic outcomes were favorable. Patients with high-grade tumors carry a high risk of recurrence, despite aggressive treatment. AJCC stage and histopathologic grade may predict outcomes and guide treatment.

3.
Am J Otolaryngol ; 45(4): 104260, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38613928

RESUMO

OBJECTIVE: The aim of the study was to trace the development of surgical therapy in a large cohort, examine its changes at one single institution that has been specializing in salivary gland pathologies over the last 22 years, and to determine the extent to which a possible shift in the surgical therapy of parotid benign tumors towards less radical methods was correlated with a change in the incidence of facial palsy and Frey's syndrome. STUDY DESIGN: Retrospective clinical study. METHODS: A retrospective evaluation of the records of all patients treated for benign parotid tumors at a tertiary referral center between 2000 and 2022 was carried out. Surgical methods were classified into four groups: extracapsular dissection, partial superficial parotidectomy, superficial parotidectomy and complete parotidectomy. RESULTS: A total of 4037 patients were included in the study. Our analysis demonstrated an increase in the total number of parotidectomies for benign lesions from 71 (2000) to 298 (2022), mostly due to the increase in extracapsular dissections (from 9 to 212). The increased performance of less radical surgery was associated with a significantly decreased incidence of perioperative complications. CONCLUSIONS: Our study showed that the increased performance of less radical surgery was associated with better functional outcomes over the years.


Assuntos
Dissecação , Paralisia Facial , Glândula Parótida , Neoplasias Parotídeas , Humanos , Estudos Retrospectivos , Neoplasias Parotídeas/cirurgia , Neoplasias Parotídeas/patologia , Masculino , Feminino , Pessoa de Meia-Idade , Glândula Parótida/cirurgia , Dissecação/métodos , Paralisia Facial/etiologia , Paralisia Facial/epidemiologia , Sudorese Gustativa/etiologia , Sudorese Gustativa/epidemiologia , Sudorese Gustativa/prevenção & controle , Adulto , Resultado do Tratamento , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Idoso , Incidência
4.
Artigo em Inglês | MEDLINE | ID: mdl-39271589

RESUMO

PURPOSE: This study aimed to evaluate the feasibility, safety, and patient satisfaction of outpatient partial parotidectomies in a French university hospital, addressing the lack of national data on such procedures amidst a push for increased ambulatory surgeries. METHODS: A prospective cohort study was conducted, involving patients undergoing partial parotidectomy for non-malignant tumors from March 2021 to May 2023. Inclusion was based on surgical, medical, and social criteria. A control group was also reviewed for comparison. The study followed a standardized surgical and anesthesia protocol, with patient satisfaction assessment. RESULTS: From an initial pool of 104, 64 patients passed surgical screening, and 45 remained after anesthesia and social considerations, marking a 70% inclusion rate for outpatient care. The success rate of outpatient procedures stood at 98%, with complication incidences mirroring those of inpatient counterparts. 91% of participants expressed high satisfaction, scoring their experiences 7/10 or above. CONCLUSION: Outpatient partial parotidectomies within the French health infrastructure are both viable and align with patient expectations, reinforcing the shift towards ambulatory surgery.

5.
Eur Arch Otorhinolaryngol ; 281(10): 5429-5436, 2024 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-38847842

RESUMO

BACKGROUND: Scar formation after neck surgery is a frequent concern, impacting patients both physically and psychologically. Cosmetic appearance plays a crucial role in assessing surgical success. At present, the evolving medical technologies introduces innovations like Geometric Electron Modulation (GEM) electrocautery. GEM technology offers potential benefits such as reduced thermal injury and consistent heat emission during surgery compared to conventional electrocautery. OBJECTIVES: To compare the difference between postoperative neck scars from the surgical blade as the gold standard and geometric electron modulation electrocautery. MATERIAL AND METHODS: A randomized controlled study was performed on the patients who were diagnosed with surgical conditions requiring neck surgery at the Department of Otolaryngology Head and Neck Surgery, King Chulalongkorn Memorial Hospital, from 2023 to 2024. The Patient and Observer Scar Assessment Scale was utilized to assess scar appearance at 1 and 3 months following the surgery, and the amount of blood loss during incision was recorded. RESULTS: 22 patients were enrolled to this study. At 1-month follow-up, we saw significant difference between GEM (20.32 ± 4.11) and the surgical blade (23.27 ± 4.59) (P = 0.008) from POSAS, patient scale but no significant difference in doctor scale, (GEM 21.55 ± 7.34, surgical blade 24.27 ± 7.88, P = 0.155). At 3-month follow-up, there were no significant difference between the groups both doctor (GEM 16.45 ± 4.62, surgical blade 17.65 ± 4.50, P = 0.411) and patient scale (GEM 13.15 ± 2.96, surgical blade 14.05 ± 3.33, P = 0.328). CONCLUSION: GEM electrocautery had a superior scar outcome to a surgical blade at 1 month from the patient perspective. There was also significantly less blood loss in GEM compared with the surgical blade.


Assuntos
Cicatriz , Eletrocoagulação , Humanos , Eletrocoagulação/métodos , Cicatriz/etiologia , Masculino , Feminino , Pessoa de Meia-Idade , Adulto , Pescoço/cirurgia , Resultado do Tratamento , Idoso , Perda Sanguínea Cirúrgica , Procedimentos Cirúrgicos Otorrinolaringológicos/métodos
6.
Eur Arch Otorhinolaryngol ; 281(10): 5555-5558, 2024 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-39025975

RESUMO

It is well known that the digastric posterior belly is one of the essential landmarks for facial nerve identification during parotid surgery. While there were multiple reports about variations of the digastric anterior belly, only a few anatomical variations of the posterior belly of the digastric muscle have been described.In this article, we describe an anatomical variation of the posterior belly of digastric muscle found during superficial parotidectomy of a patient with pleomorphic adenoma. This anatomical variation also led to an anatomical variation in the position of the facial nerve.To our knowledge, this is the first report of an absent posterior belly of digastric muscle found during live parotid surgery. The knowledge of current anatomical variation may help to avoid facial nerve injury during parotid surgery and preserve the function of muscles of facial expression.


Assuntos
Adenoma Pleomorfo , Glândula Parótida , Neoplasias Parotídeas , Humanos , Neoplasias Parotídeas/cirurgia , Glândula Parótida/cirurgia , Adenoma Pleomorfo/cirurgia , Nervo Facial/cirurgia , Nervo Facial/anormalidades , Músculos do Pescoço/anormalidades , Músculos do Pescoço/cirurgia , Masculino , Pessoa de Meia-Idade , Feminino , Traumatismos do Nervo Facial/prevenção & controle , Traumatismos do Nervo Facial/etiologia
7.
Eur Arch Otorhinolaryngol ; 281(8): 4305-4313, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38649542

RESUMO

BACKGROUND: The preoperative diagnosis of salivary gland cancer (SGC) is crucial for the application of appropriate treatment, particularly involving the extension of the resection. METHODS: Retrospective search of medical database identified 116 patients treated surgically with malignant tumors of salivary gland between 2010 and 2020. Analysis included the demographical data, clinical course, type of surgical and adjuvant treatment, histology type and margin status, perivascular invasion (LVI), perineural invasion (PNI), metastatic lymph nodes (LN). Facial nerve function, recurrence-free and overall survival were evaluated. Adequate statistics were used for data analysis. RESULTS: The final cohort included 63 SGC patients, with adenoid cystic carcinoma the most common pathological type (27%, n = 17), followed by adenocarcinoma (17.4% n = 11). T1 and T2 patients accounted for majority cases (n = 46). The lymph node metastases were confirmed with the histopathology in 31.7% (n = 20). Distant metastases were observed in 4.8% of cases (n = 3). 38% (n = 24) of SGC were treated selectively with surgery, 49.2% (n = 31) had postoperative radiotherapy and 15.9% (n = 10)-radio-chemotherapy. The final facial nerve function was impaired in 38% of patients. Mean overall survival (OS) for all patients was 108.7 (± 132.1) months, and was the most favorable for acinar cell carcinoma (118.9 ± 45.4) and the poorest for squamous cell carcinoma (44 ± 32). Cox regression analysis of disease-free survival and OS identified significant association only with patients' age over 65 years, the hazard ratio of 7.955 and 6.486, respectively. CONCLUSIONS: The efficacy of treatment modalities for SGC should be verified with regard to the histopathological type, but also the patients' age should be taken into account.


Assuntos
Neoplasias das Glândulas Salivares , Humanos , Masculino , Neoplasias das Glândulas Salivares/terapia , Neoplasias das Glândulas Salivares/patologia , Neoplasias das Glândulas Salivares/mortalidade , Feminino , Estudos Retrospectivos , Pessoa de Meia-Idade , Idoso , Adulto , Carcinoma Adenoide Cístico/terapia , Carcinoma Adenoide Cístico/patologia , Carcinoma Adenoide Cístico/mortalidade , Adenocarcinoma/terapia , Adenocarcinoma/patologia , Adenocarcinoma/mortalidade , Metástase Linfática , Idoso de 80 Anos ou mais , Adulto Jovem , Estadiamento de Neoplasias , Taxa de Sobrevida , Resultado do Tratamento
8.
Int Wound J ; 21(7): e70005, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-39040018

RESUMO

Excessive compression after parotidectomy can lead to flap necrosis, while inadequate pressure can cause fluid accumulation. This study aimed to determine the optimal pressure and compression properties of different types of dressings. Initially, pressure measurements were taken for conventional Barton's dressing and a pre-fabricated facial garment. In the subsequent phase, patients were randomly assigned to receive one of three types of pressure dressings: conforming bandage Barton's dressing, elastic bandage Barton's dressing or pre-fabricated facial garment. The dressing types were randomly crossed over the following day. The mean pressure exerted by conventional Barton's dressing and the pre-fabricated facial garment was 15.86 and 14.81 mmHg, respectively. There was no significant difference in the proportion of optimal pressure among the three types of pressure dressing (p-values of 0.195, 0.555 and 0.089 at pre-auricular, angle of mandible and post-auricular sites, respectively). The pre-auricular area demonstrated the highest proportion of optimal pressure, while suboptimal pressure was noted at the angle of the mandible and post-auricular area. Dressing types had no effect on pressure stability (p = 0.37), and there was no significant difference in patient preference (p = 0.91). Conforming bandage Barton's dressing, elastic bandage Barton's dressing and pre-fabricated facial garment exhibit comparable compressive properties, with no significant difference in patient preference and pressure stability.


Assuntos
Bandagens Compressivas , Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Adulto , Pressão , Glândula Parótida/cirurgia , Cicatrização , Bandagens , Estudos Cross-Over , Vestuário
9.
Oral Dis ; 29(1): 188-194, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34739166

RESUMO

OBJECTIVE: Deep lobe parotid tumour is commonly removed with the covering superficial lobe of parotid gland. Total or subtotal parotidectomy leads to an increase in surgical morbidity. This study evaluated recurrence and function after selective deep lobe parotidectomy via retroauricular hairline (Roh's) incision for pleomorphic adenoma. MATERIALS AND METHODS: Twenty-eight patients with deep lobe parotid pleomorphic adenomas underwent selective deep lobe parotidectomy with preservation of the superficial lobe and the facial lobe via Roh's incision. Each patient was evaluated with any complications, cosmetic and salivary functions and local recurrence. RESULTS: Superficial lobe-preserving surgery via Roh's incision was successfully applied to all patients without injury to the facial nerve and the Stensen's duct for a median operation time of 65 min. Facial nerve paralysis was found only temporarily in 9 (32%) patients, and other complications were minimal. None of the patients had postoperative Frey's syndrome. Salivary secretory function in the operated side was well preserved. No recurrence was found in the patients for a median follow-up of 94 months. CONCLUSIONS: Selective deep lobe parotidectomy via Roh's incision is a reliable option of treatment for deep lobe parotid pleomorphic adenoma.


Assuntos
Adenoma Pleomorfo , Neoplasias Parotídeas , Ferida Cirúrgica , Sudorese Gustativa , Humanos , Adenoma Pleomorfo/cirurgia , Adenoma Pleomorfo/complicações , Adenoma Pleomorfo/patologia , Complicações Pós-Operatórias/etiologia , Sudorese Gustativa/etiologia , Sudorese Gustativa/patologia , Neoplasias Parotídeas/cirurgia , Glândula Parótida/cirurgia , Glândula Parótida/patologia , Ferida Cirúrgica/complicações , Estudos Retrospectivos , Recidiva Local de Neoplasia/patologia
10.
Am J Otolaryngol ; 44(6): 103974, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37437335

RESUMO

PURPOSE: Parotidectomies are rarely performed on an outpatient basis. The specific perioperative outcomes and their management remains insufficiently described to change daily practice. The objectives were to study the outcomes, the complications and the patient satisfaction rate in parotidectomy performed on an outpatient basis. MATERIALS AND METHODS: We conducted a retrospective monocentric database study on 85 patients who underwent parotidectomy as a first and sole procedure from 2015 to 2020. We analyzed perioperative outcomes between outpatients and inpatients. RESULTS: Among 28 outpatients and 57 inpatients, no significant differences in total perioperative complications (p = .66; OR = 1.25; 95 % confidence interval (CI) [0.47; 3.36]), reoperations (p = .55), readmissions (p = 1), or unplanned visits (p = .52) were shown in multivariate analysis. The conversion rate for surgical reasons was 8.6 %, and the satisfaction rate was high. CONCLUSION: Although outpatient parotidectomies should be as safe as for inpatients, the high rate of minor complications requires specific perioperative management, such as a systematic early postoperative visit and optimized preoperative information in order to be carried out with minimal issues.


Assuntos
Pacientes Ambulatoriais , Complicações Pós-Operatórias , Humanos , Estudos Retrospectivos , Complicações Pós-Operatórias/epidemiologia , Procedimentos Cirúrgicos Ambulatórios/efeitos adversos , Procedimentos Cirúrgicos Ambulatórios/métodos , Satisfação Pessoal
11.
Am J Otolaryngol ; 44(3): 103818, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36878174

RESUMO

In this paper, we aimed at methodologically presenting a video-case of Frey Syndrome occurred after parotidectomy, assessed by means of Minor's Test and treated with intradermic botulinum toxin A (BoNT-A) injection. Although largely described in the literature, a detailed explanation of both the procedures has not been previously elucidated. In a more original approach, we also highlighted the role of the Minor's test in identifying the most affected skin areas and new insight on the patient-tailored approach provided by multiple injections of botulinum toxin. Six months after the procedure, the patient's symptoms were resolved, and no evident signs of Frey syndrome were detectable through the Minor's test.


Assuntos
Toxinas Botulínicas , Sudorese Gustativa , Humanos , Sudorese Gustativa/diagnóstico , Sudorese Gustativa/tratamento farmacológico , Sudorese Gustativa/etiologia
12.
Am J Otolaryngol ; 44(2): 103806, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36842422

RESUMO

BACKGROUND: Parotidectomies have historically been performed on an inpatient basis despite being well-tolerated surgeries with minimal postoperative wound care and low rates of complications at high-volume institutions. Past studies have supported the safety of outpatient surgery for parotidectomy but have been limited to superficial parotidectomy and have not addressed the patient experience surrounding the surgical intervention such as pre-operative and post-operative care and communication. PURPOSE: This study assesses the impact of outpatient superficial, deep, and partial parotid surgery on various parameters including surgical safety, distance traveled for care, utilization of telehealth, and patient-initiated communication. MATERIALS AND METHODS: Retrospective study from January 2020 to October 2021. Patients undergoing superficial lobe, deep lobe, and partial parotidectomies for benign and malignant pathologies were divided into inpatient and outpatient cohorts. A multivariable model examined the relationship between admission status and surgical complications, adjusted for age, sex, and tumor size. RESULTS: 159 patients total, 94 outpatient and 65 inpatients. No statistical difference in rates of surgical complications with the exception of salivary leak. There was an increased rate of salivary leak reported in the inpatient group (OR 5.4, 95 % CI 1.6 to 18.0, p = 0.01). Mean patient travel distance of 354 miles one-way. Post-operatively, 76 % were evaluated via video visit. Following discharge, >55 % of patients initiated communication with the surgical team, which was not statistically different between the groups. CONCLUSIONS: Outpatient parotidectomy is safe and can be more convenient, but telehealth communication must be balanced with rigorous attention to patient education.


Assuntos
Neoplasias Parotídeas , Humanos , Neoplasias Parotídeas/cirurgia , Neoplasias Parotídeas/patologia , Pacientes Ambulatoriais , Estudos Retrospectivos , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/patologia , Glândulas Salivares/patologia , Glândula Parótida/cirurgia , Glândula Parótida/patologia
13.
Am J Otolaryngol ; 44(6): 103973, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37429129

RESUMO

BACKGROUND: The aim of the study was to investigate primary locoregional metastatic behavior in a large sample of various malignant tumors of the parotid gland with varying grades following surgical treatment consisting of complete parotidectomy and neck dissection. METHODS: The records of all patients treated for primary malignant tumors of the parotid gland by means of complete parotidectomy and neck dissection between 2007 and 2022 were studied retrospectively. RESULTS: 196 patients formed our study sample (98 females, 98 males). The mean age was 65.7 years (22-101 years). 92 cases presented with low-grade subtypes, 19 with intermediate-grade, and 85 with high-grade carcinomas. The locoregional lymphatic network had been invaded in a total of 66/196 cases (33.6 %). The intraparotid lymph nodes were positive in 54/196 cases (27.5 %) and the cervical lymph nodes in 41/196 cases (20.9 %). In 12 out of the 66 cases with a pN+ status, the neck had been invaded without involvement of the intraparotideal lymph nodes (18.2 %). Male patients tended to suffer from more aggressive carcinomas, and high-grade subtypes presented significantly more frequently as locally advanced tumors. Higher grading was significantly associated with the involvement of the parotid (p < 0.001) and cervical (p < 0.001) lymph nodes. Intermediate and low-grade cases presented similar behavior concerning tumorous invasion of the lymphatic network of the parotid gland (p = 0.522) and the neck (p = 0.467). CONCLUSION: The locoregional metastatic potential of parotid malignant tumors depends upon a variety of histopathologic factors, which have to be considered in the decision-making process concerning the management of locoregional lymph nodes.


Assuntos
Carcinoma , Neoplasias Parotídeas , Feminino , Humanos , Masculino , Idoso , Glândula Parótida/cirurgia , Glândula Parótida/patologia , Neoplasias Parotídeas/cirurgia , Neoplasias Parotídeas/patologia , Estudos Retrospectivos , Estadiamento de Neoplasias , Metástase Linfática/patologia , Linfonodos/patologia , Esvaziamento Cervical , Carcinoma/patologia
14.
Am J Otolaryngol ; 44(3): 103824, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36889143

RESUMO

BACKGROUND: The aim of the study was to investigate primary locoregional metastatic behavior in a large sample of low-grade malignant tumors of the parotid gland following surgical treatment consisting of complete parotidectomy and neck dissection. METHODS: The records of all patients treated for low-grade malignant tumors of the parotid gland by complete parotidectomy and neck dissection between 2007 and 2022 were studied retrospectively. RESULTS: 94 patients formed our study sample (50 females, 44 males, female to male ratio: 1.14). The mean age was 59 years (range 15-95 years). The mean number of lymph nodes in the specimen from complete parotidectomy was 3.33 (range: 0-12). The mean number of involved lymph nodes in the parotid gland was 0.05 (range: 0-1). The mean number of lymph nodes in the specimen from the ipsilateral neck dissection was 16.2 (range 4-42). The mean number of involved lymph nodes in the neck dissection specimen was 0.09 (range: 0-2). Comparison of T1-T2 vs. T3-T4 cases revealed no statistically significant difference concerning the tumorous involvement of the lymphatic network (x2 = 0.719, p = 0.396). CONCLUSION: Low-grade primary malignant tumors of the parotid gland are characterized by an initially low metastatic potential, which justifies conservative forms of surgical treatment.


Assuntos
Glândula Parótida , Neoplasias Parotídeas , Humanos , Masculino , Feminino , Adolescente , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Glândula Parótida/cirurgia , Glândula Parótida/patologia , Neoplasias Parotídeas/cirurgia , Neoplasias Parotídeas/patologia , Estudos Retrospectivos , Estadiamento de Neoplasias , Metástase Linfática , Esvaziamento Cervical
15.
Eur Arch Otorhinolaryngol ; 280(12): 5219-5227, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37638999

RESUMO

BACKGROUND AND PURPOSE: Parotid gland lymphoma (PGL) is a rare and challenging diagnosis. Different lymphomas can develop in the parotid gland, with the most common being the mucosa-associated lymphoid tissue (MALT) lymphoma, which originates directly from the glandular parenchyma. Other histologic subtypes arise from both intraglandular and extraglandular parotid lymph nodes. A consensus on diagnosis and treatment of PGL is still lacking, and published data is scarce and heterogeneous. METHODS: We performed a systematic review of the literature, including studies published after 2001, when the WHO classification of lymphoid tumours was introduced. RESULTS: Twenty retrospective studies were included in the analyses, eight of which focused exclusively on MALT lymphomas. Final analysis included 612 cases of PGL, with a 1.68:1 F/M ratio. MALT lymphoma was the most common histology, followed by follicular and diffuse large B-cell lymphoma. Most cases were low stages (IE/IIE acc. Ann Arbour, 76.5%) and only 10% of patients presented with symptoms, most commonly pain (4.8%) and B symptoms (2.2%). A high prevalence of associated autoimmune diseases was found, particularly Sjögren's syndrome, that affected up to 70% of patients with MALT lymphoma. In most cases diagnosis was achieved through parotidectomy (57.5%), or open biopsy (31.2%). Treatment strategies were either surgical, non-surgical or a combination of modalities. Surgery as a single-modality treatment was reported in about 20% of patients, supposing it might be a valuable option for selected patients. CONCLUSIONS: Our review showed that the diagnosis and treatment of PGLs is far from being standardized and needs further, more homogeneous reports to reach consensus.


Assuntos
Linfoma de Zona Marginal Tipo Células B , Neoplasias Parotídeas , Síndrome de Sjogren , Humanos , Glândula Parótida/patologia , Linfoma de Zona Marginal Tipo Células B/diagnóstico , Linfoma de Zona Marginal Tipo Células B/terapia , Linfoma de Zona Marginal Tipo Células B/complicações , Estudos Retrospectivos , Glândulas Salivares/patologia , Síndrome de Sjogren/complicações , Síndrome de Sjogren/diagnóstico , Neoplasias Parotídeas/diagnóstico , Neoplasias Parotídeas/cirurgia
16.
Eur Arch Otorhinolaryngol ; 280(3): 1479-1484, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-36333562

RESUMO

PURPOSE: Facial nerve dysfunction (FND) is a frequent and serious parotidectomy outcome. Intraoperative facial nerve monitoring (IFNM) is an increasingly used technique to identify the facial nerve (FN) and minimize its injury. This study aimed to evaluate the determinant factors in the presence and severity of FND after parotidectomy, including IFNM. STUDY DESIGN, SETTING AND METHODS: A total of 48 patients consecutively submitted to parotidectomy between 2005 and 2020 in a tertiary hospital were retrospectively analyzed. The House-Brackmann Scale (HBS) was used to assess the severity of FND. RESULTS: There was a mean age of 54.2 ± 17.8 years, 50% were male. Pleomorphic adenoma (41.7%) and Warthin's tumor (25.0%) were most common. From the 23 patients (47.9%) who developed some degree of FND (HBS score of 3.41 ± 1.53), 19 (82.6%) showed facial movement recovery, with a mean recovery time of 4.78 ± 2.53 months. IFNM was performed in 39.6% of the surgeries. The use of IFNM (p = 0.514), the type of surgery-partial or total parotidectomy-(p = 0.853) and the type of histology-benign or malignant lesion-(p = 0.852) did not significantly influence the presence of FND in the postoperative period. However, in the subgroup of patients who developed FND, the HBS value was significantly lower in cases of benign pathology (p = 0.002) and in patients who underwent IFNM (p = 0.017), denoting a significantly lower severity. CONCLUSION: In the present study, IFNM and the existence of a benign lesion have been shown to be associated with lower severity of FND.


Assuntos
Traumatismos do Nervo Facial , Neoplasias Parotídeas , Humanos , Masculino , Adulto , Pessoa de Meia-Idade , Idoso , Feminino , Nervo Facial , Neoplasias Parotídeas/cirurgia , Estudos Retrospectivos , Traumatismos do Nervo Facial/etiologia , Face , Glândula Parótida/cirurgia , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/etiologia
17.
Eur Arch Otorhinolaryngol ; 280(7): 3329-3335, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-36872347

RESUMO

PURPOSE: Pleomorphic adenoma (mixed tumor) is the most common neoplasm of the parotid gland and one of the most frequent types of salivary gland tumor, generally with benign behavior and relatively slow growing. The adenomas could arise from the superficial, deep or from both superficial and deep parotid's lobes. METHODS: The aim of this review is to retrospectively analyze the surgical management of patients with pleomorphic adenoma of the parotid gland performed at the Department of Otorhinolaryngology (Department of Sense Organs of "Azienda Policlinico Umberto I" in Rome), from 2010 to 2020, with a focus on the percentage of recurrence and on the complication related to surgery to suggest an optimal diagnostic and therapeutic algorithm for patients with recurrent pleomorphic adenoma. The analysis of the complications observed in case of different surgical approaches was performed using the X2 test. RESULTS: The choice of a surgical approach (superficial parotidectomy-SP, total parotidectomy-TP, extracapsular dissection-ECD) depends on several elements, such as the location and the size of the adenoma, the availability of existing technical facilities and the professional experience of the surgeon. A transient facial palsy was present in 37.6%, 2.7% reported a permanent facial nerve palsy, 1.6% developed a salivary fistula, 1.6% a post-operative bleeding and 2.3% showed Frey Syndrome. CONCLUSION: The surgical management of this benign lesion is required, even in asymptomatic cases, to prevent the progressive growing and to reduce the risk of malignant transformation. The goal of surgical excision is to obtain the complete resection to minimize the risk of tumor recurrence and avoiding facial nerve disability. Therefore, an accurate preoperative study of the lesion and the choice of the most appropriate surgical treatment are essential to minimize the rate of recurrence.


Assuntos
Adenoma Pleomorfo , Paralisia de Bell , Paralisia Facial , Neoplasias Parotídeas , Humanos , Adenoma Pleomorfo/diagnóstico , Adenoma Pleomorfo/cirurgia , Adenoma Pleomorfo/patologia , Estudos Retrospectivos , Neoplasias Parotídeas/diagnóstico , Neoplasias Parotídeas/cirurgia , Neoplasias Parotídeas/patologia , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/patologia , Glândulas Salivares/patologia , Glândula Parótida/cirurgia , Glândula Parótida/patologia , Paralisia Facial/etiologia , Paralisia Facial/patologia , Recidiva Local de Neoplasia/diagnóstico , Recidiva Local de Neoplasia/cirurgia , Recidiva Local de Neoplasia/patologia
18.
Surg Innov ; 30(2): 210-217, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36128913

RESUMO

OBJECTIVE: The mainstay of first-line treatment of parotid tumors is adequate surgical removal. The present study was conducted to compare the differences between parotidectomy with postauricular incision (PI) and modified Blair incision (MBI). DATA SOURCES: A systematic search of PubMed, Embase and the Cochrane Library was performed. METHODS: The data of interest and study characteristics were extracted from the included studies. Statistical analysis was performed with Comprehensive Meta-Analysis software (version 3; BioStat, Englewood, NJ). Dichotomous data and continuous data were analyzed by calculating the risk difference and the mean difference with the 95% confidence interval respectively. RESULTS: Four retrospective studies were included in the present meta-analysis. The pooled results revealed that the cosmetic satisfaction score was higher in the PI group (MD = 2.67; 95% CI, 2.12 to 3.23) and that intraoperative blood loss was lower in the PI group (MD = -55.35; 95% CI, -100.33 to -10.36). The operative duration (MD = -5.15; 95% CI, -24.06 to 13.75), tumor size (MD = -.07; 95% CI, -.27 to .13) and incidences of common postoperative complications were comparable between the two groups. CONCLUSIONS: According to these findings, the use of PI in parotidectomies may be one of the options for improving cosmetic outcomes. This technique may be considered if oncological safety can be secured.


Assuntos
Neoplasias Parotídeas , Ferida Cirúrgica , Humanos , Estudos Retrospectivos , Neoplasias Parotídeas/cirurgia , Neoplasias Parotídeas/patologia , Complicações Pós-Operatórias/epidemiologia , Perda Sanguínea Cirúrgica/prevenção & controle
19.
HNO ; 71(3): 145-153, 2023 Mar.
Artigo em Alemão | MEDLINE | ID: mdl-36512059

RESUMO

BACKGROUND: Salivary gland diseases are an important part of the work of ENT physicians in hospitals. The treatment strategies depend, among other things, on the doctrine at the respective location. OBJECTIVE: The aim of this questionnaire-based study was to assess the current diagnostic workup and therapeutic strategies for salivary gland diseases in German otorhinolaryngology departments. MATERIALS AND METHODS: A survey was performed using a 25-question online questionnaire sent to all German otorhinolaryngology department directors. RESULTS: The questionnaire was answered by 92 of 175 otorhinolaryngology departments (52.6%). In the diagnosis of salivary gland tumors, a dominance of sonography and MRI was shown. Fine- and core-needle aspiration were not performed by more than 50% of the clinics. The dominant technique for parotidectomy was under microscopic control (82%). In 99% of clinics, EMG was used during resection of the parotid gland for intraoperative monitoring of the facial nerve. There was a trend towards performing partial parotidectomies (85%), lateral parotidectomies (70%), and extracapsular dissections (57%) for benign tumors of the parotid gland. The treatment concepts for malignant tumors were inconsistent. CONCLUSION: In particular, the treatment strategy and extent of surgery for benign and malignant salivary gland tumors differed depending on location. The choice of palliative (drug) therapy was also diverse. Prospective multicenter studies could help to develop evidence-based treatment strategies.


Assuntos
Neoplasias Parotídeas , Doenças das Glândulas Salivares , Neoplasias das Glândulas Salivares , Humanos , Neoplasias Parotídeas/cirurgia , Estudos Prospectivos , Doenças das Glândulas Salivares/patologia , Glândula Parótida/patologia , Glândula Parótida/cirurgia , Hospitais , Inquéritos e Questionários , Estudos Retrospectivos
20.
J Pak Med Assoc ; 73(2): 412-415, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36800741

RESUMO

Mammary analogue secretory carcinoma (MASC) is a salivary gland tumour with low-grade potential and specific FTV6 derangement having translocation of chromosomes t (12;15) (p13;q25). It shares a similar morphological as well as an immunohistochemical profile with secretory carcinoma (SC) of the breast making it a diagnostic enigma. In this report, we discuss the case of a 65-year-old male patient, who presented with a complaint of right-sided facial swelling. To rule out the differential, he underwent various diagnostic modalities, including magnetic resonance imaging, fine-needle aspiration and it's the tumour's microscopic and immunohistochemical properties were also reviewed. Parotidectomy along with concurrent chemo-radiotherapy was performed to eradicate the growing mass.


Assuntos
Neoplasias da Mama , Carcinoma , Carcinoma Secretor Análogo ao Mamário , Masculino , Humanos , Idoso , Glândula Parótida/diagnóstico por imagem , Carcinoma Secretor Análogo ao Mamário/diagnóstico , Carcinoma Secretor Análogo ao Mamário/terapia , Carcinoma/diagnóstico por imagem , Carcinoma/terapia , Biópsia por Agulha Fina
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