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1.
Int J Audiol ; : 1-10, 2024 May 28.
Artigo em Inglês | MEDLINE | ID: mdl-38804563

RESUMO

OBJECTIVE: Evaluate the ability of an extended version of the 3 MTM Eargage to estimate the earcanal size and assess the likelihood that a particular earplug can fit an individual's earcanal, ultimately serving as a tool for selecting earplugs in the field. DESIGN: Earcanal morphology, assessed through earcanal earmolds scans, is compared to earcanal size assessed with the extended eargage (EE) via box plots and Pearson linear correlations coefficients. Relations between attenuation measured on participants (for 6 different earplugs) and their earcanal size assessed with the EE are established via comparison tests. STUDY SAMPLE: 121 participants exposed to occupational noise (103 men, 18 women, mean age 47 years). RESULTS: The earcanal size assessed with the EE allows for estimating the area of the earcanal's first bend cross-section (correlation coefficient  r = 0.533, p < 0.001). Extremely large earcanals (12.7% of earcanals in our sample) lead to significantly lower earplug attenuation (potentially inadequate) than smaller earcanals. CONCLUSIONS: The EE is a simple and inexpensive tool easily deployable in the field to assist earplugs selection. When extended with sizes larger than the maximum size of the commercial tool, it allows for detecting individuals with extremely large earcanals who are most likely to be under-protected.

2.
Int J Mol Sci ; 25(12)2024 Jun 07.
Artigo em Inglês | MEDLINE | ID: mdl-38928015

RESUMO

Noise-induced hearing loss (NIHL) is a major cause of hearing impairment and is linked to dementia and mental health conditions, yet no FDA-approved drugs exist to prevent it. Downregulating the mitogen-activated protein kinase (MAPK) cellular pathway has emerged as a promising approach to attenuate NIHL, but the molecular targets and the mechanism of protection are not fully understood. Here, we tested specifically the role of the kinases ERK1/2 in noise otoprotection using a newly developed, highly specific ERK1/2 inhibitor, tizaterkib, in preclinical animal models. Tizaterkib is currently being tested in phase 1 clinical trials for cancer treatment and has high oral bioavailability and low predicted systemic toxicity in mice and humans. In this study, we performed dose-response measurements of tizaterkib's efficacy against permanent NIHL in adult FVB/NJ mice, and its minimum effective dose (0.5 mg/kg/bw), therapeutic index (>50), and window of opportunity (<48 h) were determined. The drug, administered orally twice daily for 3 days, 24 h after 2 h of 100 dB or 106 dB SPL noise exposure, at a dose equivalent to what is prescribed currently for humans in clinical trials, conferred an average protection of 20-25 dB SPL in both female and male mice. The drug shielded mice from the noise-induced synaptic damage which occurs following loud noise exposure. Equally interesting, tizaterkib was shown to decrease the number of CD45- and CD68-positive immune cells in the mouse cochlea following noise exposure. This study suggests that repurposing tizaterkib and the ERK1/2 kinases' inhibition could be a promising strategy for the treatment of NIHL.


Assuntos
Perda Auditiva Provocada por Ruído , Animais , Camundongos , Administração Oral , Perda Auditiva Provocada por Ruído/tratamento farmacológico , Masculino , Inibidores de Proteínas Quinases/farmacologia , Inibidores de Proteínas Quinases/administração & dosagem , Sistema de Sinalização das MAP Quinases/efeitos dos fármacos , Feminino , Modelos Animais de Doenças , Cóclea/efeitos dos fármacos , Cóclea/metabolismo
3.
J Occup Environ Hyg ; 21(1): 68-76, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37843505

RESUMO

Hearing protection device (HPD) fit-testing is a recommended best practice for hearing conservation programs as it yields a metric of the amount of attenuation an individual achieves with an HPD. This metric, the personal attenuation rating (PAR), provides hearing health care, safety, and occupational health personnel the data needed to select the optimal hearing protection for the occupational environment in which the HPD will be worn. Although commercial-off-the-shelf equipment allows the professional to complete HPD fit tests in the field, a standard test methodology does not exist across HPD fit-test systems. The purpose of this study was to compare the amount of attenuation obtained using the "gold standard" laboratory test (i.e., real-ear attenuation at threshold [REAT]) and three commercially available HPD fit-test systems (i.e., Benson Computer Controlled Fit Test System [CCF-200] with narrowband noise stimuli, Benson CCF-200 with pure tone stimuli, and Michael and Associates FitCheck Solo). A total of 57 adults, aged 18 to 63, were enrolled in the study and tested up to seven earplugs each across all fit-test systems. Once fitted by a trained member of the research team, earplugs remained in the ear throughout testing across test systems. Results revealed a statistically significant difference in measured group noise attenuation between the laboratory and field HPD fit-test systems (p < .0001). The mean attenuation was statistically significantly different (Benson CCF-200 narrowband noise was +3.1 dB, Benson CCF-200 pure tone was +2.1 dB, and Michael and Associates FitCheck Solo was +2.5 dB) from the control laboratory method. However, the mean attenuation values across the three experimental HPD fit-test systems did not reach statistical significance and were within 1.0 dB of one another. These findings imply consistency across the evaluated HPD fit-test systems and agree with the control REAT test method. Therefore, the use of each is acceptable for obtaining individual PARs outside of a laboratory environment.


Assuntos
Perda Auditiva Provocada por Ruído , Ruído Ocupacional , Exposição Ocupacional , Saúde Ocupacional , Adulto , Humanos , Perda Auditiva Provocada por Ruído/prevenção & controle , Ruído Ocupacional/prevenção & controle , Dispositivos de Proteção das Orelhas , Exposição Ocupacional/prevenção & controle
4.
Artigo em Zh | MEDLINE | ID: mdl-39223044

RESUMO

Objective: To measure and compare the difference of personal attenuation rating (PAR) of the workers wearing foam earplugs before and after the training, and to evaluate the effect of ear protector wearing training on the noise protection. Methods: In February 2023, 94 workers exposed to noise in a machinery manufacturing factory were selected as subjects. The production noise in the workplace was measured and subjects were trained to wear earplugs. The PAR values of wearing 3M 1110 foam test earplugs were measured and recorded before and after the training by using the fit testing of hearing protection device. The differences between the actual PAR values with nominal values and the noise attenuation values in related standards were compared, and the protective effect of hearing protection device before and after training was evaluated. Results: The average age of the subjects was (36.76±11.48) years old, the average length of service was (16.34±11.64) years, and the average exposure time to noise was (15.67±11.64) years. The noise detection results of the subjects' posts were ranged from 80.1 to 94.3 dB (A). The results of subjects wore 3M 1110 foam test earplugs for fit testing showed that the binaural PAR value after training was (19.3±6.4) dB (A), which was significantly higher than that before training (11.1±7.4) dB (A) (t=13.31, P<0.001). After training, 11 people (11.70%) could reach the corrected noise reduction value (NRR value), 26 people (27.66%) could reach the standard of single noise reduction value (SNR value) ×0.6, and 84 people (89.36%) could reach the standard of (NRR-7) /2. The under protection rate of hearing protectors after training (7.45%) was significantly lower than that before training (45.74%), and the difference of different protection levels before and after training was statistically significant (χ(2)=40.83, P<0.001) . Conclusion: It is suggested that enterprises should use the fit testing instead of nominal value estimation to evaluate the noise reduction effect of hearing protection device. Special training on the selection and use of hearing protection device should be strengthened, so as to ensure that workers wear them correctly and improve the protective effect of hearing protection device.


Assuntos
Dispositivos de Proteção das Orelhas , Perda Auditiva Provocada por Ruído , Ruído Ocupacional , Exposição Ocupacional , Humanos , Ruído Ocupacional/prevenção & controle , Ruído Ocupacional/efeitos adversos , Adulto , Exposição Ocupacional/prevenção & controle , Perda Auditiva Provocada por Ruído/prevenção & controle , Masculino , Pessoa de Meia-Idade , Feminino , Local de Trabalho
5.
Neurobiol Dis ; 183: 106176, 2023 07.
Artigo em Inglês | MEDLINE | ID: mdl-37263384

RESUMO

Aminoglycoside antibiotics (AGAs) are widely used in life-threatening infections, but they accumulate in cochlear hair cells (HCs) and result in hearing loss. Increases in adenosine triphosphate (ATP) concentrations and P2X7 receptor expression were observed after neomycin treatment. Here, we demonstrated that P2X7 receptor, which is a non-selective cation channel that is activated by high ATP concentrations, may participate in the process through which AGAs enter hair cells. Using transgenic knockout mice, we found that P2X7 receptor deficiency protects HCs against neomycin-induced injury in vitro and in vivo. Subsequently, we used fluorescent gentamicin-Fluor 594 to study the uptake of AGAs and found fluorescence labeling in wild-type mice but not in P2rx7-/- mice in vitro. In addition, knocking-out P2rx7 did not significantly alter the HC count and auditory signal transduction, but it did inhibit mitochondria-dependent oxidative stress and apoptosis in the cochlea after neomycin exposure. We thus conclude that the P2X7 receptor may be linked to the entry of AGAs into HCs and is likely to be a therapeutic target for auditory HC protection.


Assuntos
Aminoglicosídeos , Ototoxicidade , Animais , Camundongos , Aminoglicosídeos/toxicidade , Aminoglicosídeos/metabolismo , Receptores Purinérgicos P2X7/metabolismo , Ototoxicidade/metabolismo , Antibacterianos/toxicidade , Neomicina/toxicidade , Neomicina/metabolismo , Células Ciliadas Auditivas/metabolismo , Cóclea , Trifosfato de Adenosina/metabolismo
6.
Int J Audiol ; : 1-8, 2023 Nov 20.
Artigo em Inglês | MEDLINE | ID: mdl-37982731

RESUMO

OBJECTIVE: Young adults are at risk for hearing loss caused by exposure to loud music. Intervention at this stage provides opportunities to support lifelong hearing protection use. This study explores attitudes related to hearing, hearing loss, and hearing protection among university students. DESIGN: Qualitative interview design, supplemented by quantitative questionnaire data. STUDY SAMPLE: 18 university students, aged 18-24 years. RESULTS: Students were uncertain about mechanisms of noise-induced hearing loss, did not feel vulnerable to permanent hearing damage from loud music, were unconvinced of hearing protection efficacy, and reported barriers to hearing protection use. Students emphasised the positive effects of loud music and reported an increased likelihood of using hearing protection were it used by peers. Music students appeared more aware of the negative effects of loud music exposure. Students reported conflicting attitudes regarding government regulation of hearing protection use. CONCLUSION: Young adults require education about hearing protection from multiple, credible sources and need to understand the mechanisms behind noise-induced hearing loss in a way that makes it of high personal relevance.

7.
Sensors (Basel) ; 23(17)2023 Aug 25.
Artigo em Inglês | MEDLINE | ID: mdl-37687865

RESUMO

Combat soldiers are currently faced with using a hearing-protection device (HPD) at the cost of adequately detecting critical signals impacting mission success. The current study tested the performance of the Perforated-Concave-Earplug (pCEP), a proof-of-concept passive HPD consisting of a concave bowl-like rigid structure attached to a commercial roll-down earplug, designed to improve sound localization with minimal compromising of noise attenuation. Primarily intended for combat/military training settings, our aim was an evaluation of localization of relevant sound sources (single/multiple gunfire, continuous noise, spoken word) compared to 3M™-Combat-Arms™4.1 earplugs in open-mode and 3M™-E-A-R™-Classic™ earplugs. Ninety normal-hearing participants, aged 20-35 years, were asked to localize stimuli delivered from monitors evenly distributed around them in no-HPD and with-HPD conditions. The results showed (1) localization abilities worsened using HPDs; (2) the spoken word was localized less accurately than other stimuli; (3) mean root mean square errors (RMSEs) were largest for stimuli emanating from rear monitors; and (4) localization abilities corresponded to HPD attenuation levels (largest attenuation and mean RMSE: 3M™-E-A-R™-Classic™; smallest attenuation and mean RMSE: 3M™-Combat-Arms™4.1; pCEP was mid-range on both). These findings suggest that the pCEP may benefit in military settings by providing improved sound localization relative to 3M™ E-A-R™-Classic™ and higher attenuation relative to 3M™-Combat Arms™-4.1, recommending its use in noisy environments.


Assuntos
Militares , Localização de Som , Humanos , Dispositivos de Proteção das Orelhas , Som
8.
J Occup Environ Hyg ; 20(2): 120-128, 2023 02.
Artigo em Inglês | MEDLINE | ID: mdl-36445186

RESUMO

Agricultural workers are more prone to noise-induced hearing loss than are many other workers. Hearing protection device use among agricultural workers is low, but training can increase hearing protection device use. This work proposes a system designed to automatically inform agricultural workers when they were exposed to noises that exceed the National Institute for Occupational Safety and Health (NIOSH) recommended exposure level. The smartphone-based system worn on the arm uses a noise dosimeter to measure noise exposures throughout the day to within ±2 A-weighted decibels of a Class 2 sound level meter. The device collects location and audio data, which are transferred to a server and presented to the worker on a locally hosted website. The website details noise exposure and helps the worker identify where exposure occurred and what specific tasks exceed NIOSH's recommended exposure limit, putting them at higher risk of noise-induced hearing loss. With this understanding, the worker is expected to adopt behavior changes and better hearing protection use at critical places and times. This pilot study evaluates the accuracy of the noise dosimeter and GPS relative to gold-standard instruments. The system was tested on a farm with outputs compared with gold-standard instruments. A-weighted, 1-sec averaged sound pressure levels and position data were collected while users were performing a variety of tasks indoors and outdoors. The smartphone's external noise dosimeter read within ±2 A-weighted decibels of the Class 2 reference dosimeter 59% of the time. The positioning devices had an average error of sub-4 m. While not perfectly matching gold-standard instruments, the device is capable of identifying and collecting information relative to loud noise events that promote noise-induced hearing loss.


Assuntos
Perda Auditiva Provocada por Ruído , Ruído Ocupacional , Exposição Ocupacional , Saúde Ocupacional , Humanos , Perda Auditiva Provocada por Ruído/etiologia , Perda Auditiva Provocada por Ruído/prevenção & controle , Ruído Ocupacional/efeitos adversos , Ruído Ocupacional/prevenção & controle , Projetos Piloto
9.
Int Arch Occup Environ Health ; 95(8): 1647-1659, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-35474491

RESUMO

OBJECTIVE: Workers from various industries use personal protective equipment (PPE) including masks, respirators, and hearing protection to reduce their exposures to workplace hazards. Many studies have evaluated the physiological impacts of PPE use, but few have assessed the psychological impacts. The aim of the present study was to carry out a scoping review to compile existing evidence and determine the extent of knowledge on workplace mask, respirator or hearing protection use as a psychosocial hazard (stressor) that could result in a stress response and potentially lead to psychological injury. METHODS: The scoping review followed recognized methods and was conducted using Ovid Emcare, PubMed, Sage Journals, ScienceDirect, Scopus, SpringerLink, Google Scholar and preprint databases (OSF Preprints and medRxiv). Articles on the stressors associated with the use of masks, respirators, and hearing protection were included. The extracted data included author(s) name, year of publication, title of article, study design, population data, stressors assessed, and key findings. RESULTS: We retrieved 650 articles after removal of duplicates, of which 26 were deemed eligible for inclusion for review. Identified factors associated with PPE use that could potentially create a stress response were identified: communication impacts, physical impacts, psychological illness symptoms, cognitive impacts, and perceived PPE-related impacts. Evidence for respirators suggest that there may be psychological injury associated with their use. However, hearing protection appears to have a protective effect in reducing psychological symptoms such as anxiety, depression, and aggression. CONCLUSIONS: Mask or respirator use may lead to an increase in work-related stress. Whereas hearing protection may have protective effects against psychological symptoms and improves speech intelligibility. More research is needed to better understand potential psychosocial impacts of mask, respirator and/or hearing protection use.


Assuntos
Angústia Psicológica , Dispositivos de Proteção Respiratória , Pessoal de Saúde , Audição , Humanos , Equipamento de Proteção Individual , Local de Trabalho
10.
Int J Audiol ; 61(6): 463-472, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-34406107

RESUMO

OBJECTIVE: The current study aimed to: i) determine the patterns of hearing protection device (HPD) use in early-career musicians, ii) identify barriers to and facilitators of HPD use, and iii) use the Behaviour Change Wheel (BCW) to develop an intervention to increase uptake and sustained use of HPDs. DESIGN: A mixed-methods approach using questionnaires and semi-structured interviews. STUDY SAMPLE: Eighty early-career musicians (age range = 18-26 years; women n = 39), across all categories of musical instrument. RESULTS: 42.5% percent of participants reported using HPDs at least once a week, 35% less than once a week, and 22.5% reported never using HPDs for music-related activities. Six barriers and four facilitators of HPD use were identified. Barriers include the impact of HPDs on listening to music and performing, and a lack of concern about noise exposure. Barriers/facilitators were mapped onto the Theoretical Domains Framework. Following the systematic process of the BCW, our proposed intervention strategies are based on 'Environmental Restructuring', such as providing prompts to increase awareness of noisy settings, and 'Persuasion/Modelling', such as providing credible role models. CONCLUSIONS: For the first time, the present study demonstrates the use of the BCW for designing interventions in the context of hearing conservation.


Assuntos
Perda Auditiva Provocada por Ruído , Música , Adolescente , Adulto , Dispositivos de Proteção das Orelhas , Feminino , Audição , Perda Auditiva Provocada por Ruído/etiologia , Perda Auditiva Provocada por Ruído/prevenção & controle , Humanos , Masculino , Ruído , Adulto Jovem
11.
HNO ; 70(12): 891-902, 2022 Dec.
Artigo em Alemão | MEDLINE | ID: mdl-36269381

RESUMO

BACKGROUND: Perfect hearing is crucial to the practice of various professions, such as instrument makers, musicians, sound engineers, and other professions not related to music, such as sonar technicians. For people of these occupational groups, we propose the term "professional ear user" (PEU) in analogy to "professional voice user". PEUs have special requirements for their hearing health, as they have well-known above-average auditory perceptual abilities on which they are professionally dependent. OBJECTIVE: The purpose of this narrative review is to summarize selected aspects of the prevention, diagnosis, and treatment of ear disorders in PEUs. RESULTS AND CONCLUSION: Prevention of hearing disorders and other ear diseases includes protection from excessive sound levels, avoidance of ototoxins and nicotine, and a safe manner of cleaning the outer auditory canal. Diagnosing hearing disorders in PEUs can be challenging, since subclinical but relevant changes in hearing cannot be reliably objectified by conventional audiometric methods. Moreover, the fact that a PEU is affected by an ear disease may influence treatment decisions. Further, physicians must be vigilant for non-organic ear diseases in PEUs. Lastly, measures to promote comprehensive ear health in PEUs as part of an educational program and to maintain ear health by means of a specialized otolaryngology service are discussed. In contrast to existing concepts, we lay the attention on the entirety of occupational groups that are specifically dependent on their ear health in a professional setting. In this context, we suggest avoiding a sole focus on hearing disorders and their prevention, but rather encourage the maintenance of a comprehensive ear health.


Assuntos
Otopatias , Perda Auditiva Provocada por Ruído , Música , Doenças Profissionais , Humanos , Perda Auditiva Provocada por Ruído/diagnóstico , Doenças Profissionais/diagnóstico , Doenças Profissionais/prevenção & controle , Audiometria
12.
Am J Ind Med ; 64(12): 1002-1017, 2021 12.
Artigo em Inglês | MEDLINE | ID: mdl-34597431

RESUMO

BACKGROUND: This study estimated the prevalence of hearing protection device (HPD) non-use among US workers exposed to hazardous workplace noise and provided risk estimates. METHODS: Self-reported data from the National Health Interview Survey in 2007 (15,852 workers) and 2014 (23,656 workers) were examined. Weighted prevalence and adjusted prevalence ratios of HPD non-use (using HPDs half the time or less when exposed to hazardous noise) were estimated by demographic, industry, and occupation. Differences in the prevalences of non-use were estimated and compared. RESULTS: The prevalence of HPD non-use was 53% among all noise-exposed workers in 2014. Workers in the Accommodation and Food Services industry had the highest prevalence (90%) and risk (PR: 2.47, 95% confidence interval: 1.54-3.96) of HPD non-use. The industries with the lowest prevalences of noise exposure, including Finance and Insurance (2%) and Health Care and Social Assistance (4%), had some of the highest prevalences of HPD non-use (80% and 83%, respectively). There were no statistically significant changes in HPD non-use among industries between 2007 and 2014. Among occupations, HPD non-use increased 37% in Arts, Design, Entertainment, Sports and Media, and decreased 39% in Architecture and Engineering. CONCLUSION: The prevalence of HPD non-use remains high; especially within industries and occupations with fewer noise-exposed workers. These groups need targeted attention to increase awareness and compliance. Employers should require HPD use and trainings among noise-exposed workers and provide an assortment of HPDs tailored to noise level and type, workplace environment, communication and audibility needs, and individual comfort and convenience.


Assuntos
Perda Auditiva Provocada por Ruído , Ruído Ocupacional , Exposição Ocupacional , Dispositivos de Proteção das Orelhas , Audição , Perda Auditiva Provocada por Ruído/epidemiologia , Humanos , Ruído Ocupacional/efeitos adversos , Exposição Ocupacional/análise , Prevalência
13.
Am J Ind Med ; 64(9): 771-780, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-34250617

RESUMO

BACKGROUND: The purpose of this study was twofold: (1) to measure the personal attenuation ratings (PARs) in Chinese workers wearing hearing protection devices (HPDs), to evaluate the effectiveness of the single number rating (SNR), the noise reduction rating (NRR), and the associated derated values of earplugs; and (2) to evaluate the effectiveness of one-on-one training along with earplug fit testing on PAR improvement. METHODS: Noise exposure measurements, one-on-one training, and fit tests to measure earplug attenuation were conducted at nine manufacturing facilities located in eastern China from 2016 to 2017. 503 workers participated in the study. Ninety-three percent were male. 199 workers were provided one-on-one training. RESULTS: Before training, 14% and 15% of the workers achieved the attenuation predicted by the manufacturer's SNR and NRR, 56% and 65% exceeded the derated SNR and NRR, respectively. Following one-on-one training, mean PAR improved significantly by 15 dB (p < 0.01); 26% of the workers achieved SNR and NRR, 79% and 91% met the associated derated values, respectively. CONCLUSIONS: Labeled noise attenuation ratings and their derated values overestimated the actual level of attenuation among workers wearing HPDs. One-on-one training along with earplug fit testing contributed to improved PARs.


Assuntos
Perda Auditiva Provocada por Ruído , Ruído Ocupacional , China , Dispositivos de Proteção das Orelhas , Perda Auditiva Provocada por Ruído/prevenção & controle , Humanos , Masculino , Instalações Industriais e de Manufatura
14.
Int J Audiol ; 60(1): 60-69, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-32749172

RESUMO

OBJECTIVE: To properly measure the effective noise exposure level of workers with hearing protection devices (HPD), the use of in-ear noise dosimeters (IEND) is increasing. Commercial IENDs typically feature one in-ear microphone that captures all noises inside the ear and do not discriminate the residual noise in the earcanal from wearer-induced disturbances (WID) to calculate the in-ear sound pressure levels (SPL). A method to alleviate this particular issue with IENDs and calculate the hearing protection level on-site is therefore proposed. DESIGN: The sound captured by an outer-ear microphone is filtered with the modelled HPD transfer function to estimate the in-ear SPL, this way part of the WIDs mostly captured by the in-ear microphone can be rejected from the SPL. The level of protection provided by the earplugs can then be estimated from the difference between in-ear and outer-ear SPLs. The proposed method is validated by comparing the outcome of the proposed WID rejection method to a reference method. STUDY SAMPLE: The detailed methods are assessed on audio recordings from 16 industrial workers monitored for up to 4 days. RESULTS: The merits of the proposed WID rejection approach are discussed in terms of residual SPL and hearing protection level estimation accuracy. CONCLUSIONS: Based on the findings, a method to integrate the proposed WID rejection algorithm in future IENDs is suggested.


Assuntos
Perda Auditiva Provocada por Ruído , Ruído Ocupacional , Dispositivos de Proteção das Orelhas , Audição , Perda Auditiva Provocada por Ruído/etiologia , Perda Auditiva Provocada por Ruído/prevenção & controle , Humanos , Ruído Ocupacional/efeitos adversos , Ruído Ocupacional/prevenção & controle , Projetos Piloto
15.
Int J Audiol ; 60(2): 151-159, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-32924674

RESUMO

OBJECTIVE: The purpose of this fit-testing study in the field was to systematically compare three Hearing Protection Device (HPD) fit-training methods and determine whether they differ in the acquisition of HPD fitting skill and resulting amount of earplug attenuation. DESIGN: Subjects were randomly assigned to receive HPD fit-training using one of three training methods: current, experiential HPD (eHPD), and integrated. Personal Attenuation Ratings (PARs) were acquired via HPD fit-testing and used to verify attenuations pre- and post-training. STUDY SAMPLE: US Marine training recruits (n = 341) identified via HPD fit-testing for remedial HPD fit-training and assigned to three cohorts. RESULTS: The post-training HPD fit-test passing rate differed by training method, with pass rates ranging from 50% (current) to nearly 92% (eHPD). The difference between group delta PAR values were significantly higher (>9 dB) in both the eHPD and integrated methods compared to the current method. CONCLUSION: The HPD fit-training methods that teach "what right feels like" (eHPD and integrated) provided a greater number of trainees with the skill to achieve noise attenuation values required for impulse noise exposures encountered during basic training. The attenuation achieved by those methods was significantly greater than the current training method.


Assuntos
Perda Auditiva Provocada por Ruído , Militares , Ruído Ocupacional , Dispositivos de Proteção das Orelhas , Audição , Perda Auditiva Provocada por Ruído/etiologia , Perda Auditiva Provocada por Ruído/prevenção & controle , Humanos
16.
Int J Mol Sci ; 22(6)2021 Mar 11.
Artigo em Inglês | MEDLINE | ID: mdl-33799684

RESUMO

Age-related hearing loss (ARHL), a sensorineural hearing loss of multifactorial origin, increases its prevalence in aging societies. Besides hearing aids and cochlear implants, there is no FDA approved efficient pharmacotherapy to either cure or prevent ARHL. We hypothesized that selegiline, an antiparkinsonian drug, could be a promising candidate for the treatment due to its complex neuroprotective, antioxidant, antiapoptotic, and dopaminergic neurotransmission enhancing effects. We monitored by repeated Auditory Brainstem Response (ABR) measurements the effect of chronic per os selegiline administration on the hearing function in BALB/c and DBA/2J mice, which strains exhibit moderate and rapid progressive high frequency hearing loss, respectively. The treatments were started at 1 month of age and lasted until almost a year and 5 months of age, respectively. In BALB/c mice, 4 mg/kg selegiline significantly mitigated the progression of ARHL at higher frequencies. Used in a wide dose range (0.15-45 mg/kg), selegiline had no effect in DBA/2J mice. Our results suggest that selegiline can partially preserve the hearing in certain forms of ARHL by alleviating its development. It might also be otoprotective in other mammals or humans.


Assuntos
Envelhecimento/fisiologia , Modelos Animais de Doenças , Perda Auditiva Neurossensorial/tratamento farmacológico , Selegilina/farmacologia , Administração Oral , Animais , Antiparkinsonianos/administração & dosagem , Antiparkinsonianos/farmacologia , Limiar Auditivo/efeitos dos fármacos , Limiar Auditivo/fisiologia , Potenciais Evocados Auditivos do Tronco Encefálico/efeitos dos fármacos , Potenciais Evocados Auditivos do Tronco Encefálico/fisiologia , Perda Auditiva Neurossensorial/fisiopatologia , Humanos , Masculino , Camundongos Endogâmicos BALB C , Camundongos Endogâmicos DBA , Substâncias Protetoras/administração & dosagem , Substâncias Protetoras/farmacologia , Selegilina/administração & dosagem , Transmissão Sináptica/efeitos dos fármacos , Transmissão Sináptica/fisiologia
17.
BMC Public Health ; 20(1): 1529, 2020 Oct 09.
Artigo em Inglês | MEDLINE | ID: mdl-33036596

RESUMO

BACKGROUND: Hearing loss is prevalent and disabling, yet little is known about the extent of recreational noise exposure and hearing protection use. The aim of the present research was to estimate the extent of recreational noise exposure and hearing protection use in a sample representative of the UK adult population. METHODS: We conducted a cross-sectional survey of 10,401 UK adults who were representative of the population. RESULTS: More than 7000 people (n = 7590, 73.0%) reported exposure to recreational noise excluding headphone and earphone use in the last 12 months. Just 158 people (2.1%) reported wearing hearing protection for every noisy recreational activity. Age (younger people) and beliefs of a behavioral (as opposed to genetic) cause of hearing loss were predictive of both higher recreational noise exposure and greater hearing protection use. Men were more exposed to recreational noise but women were less likely to use hearing protection. CONCLUSIONS: For the first time, the present research quantifies the recreational noise exposure and low levels of hearing protection use in a representative sample of the UK population. The biggest public health gains are likely to be achieved through interventions targeted at younger people and in explaining behavioral (as opposed to genetic) causes of hearing loss.


Assuntos
Dispositivos de Proteção das Orelhas , Perda Auditiva Provocada por Ruído , Adulto , Estudos Transversais , Feminino , Audição , Perda Auditiva Provocada por Ruído/epidemiologia , Perda Auditiva Provocada por Ruído/etiologia , Perda Auditiva Provocada por Ruído/prevenção & controle , Humanos , Masculino , Reino Unido/epidemiologia
18.
BMC Public Health ; 20(1): 1376, 2020 Sep 13.
Artigo em Inglês | MEDLINE | ID: mdl-32919462

RESUMO

BACKGROUND: Hearing loss and tinnitus are global concerns that can be reduced through hearing protection behaviors (e.g., earplug use). Little is known about the effectiveness of interventions to increase hearing protection use in recreational domains. For the first time we review systematically the effectiveness of such interventions. METHODS: Systematic searches of nine databases, as well as grey literature and hand-searching, were conducted. Any study design was included if it assessed quantitatively a purposeful attempt to increase hearing protection in recreational settings. Studies were excluded if they assessed noise exposure from occupational sources and headphones/earphones, as these have been reviewed elsewhere. PROSPERO protocol: CRD42018098573. RESULTS: Eight studies were retrieved following the screening of 1908 articles. Two pretest-posttest studies detected a small to medium effect (d ≥ 0·3 ≤ 0·5), one a small effect (d ~ =0·2) and two no real effect. Three posttest experimental studies detected small to medium effects (d ≥ 0·3 ≤ 0·5). Studies were rated as "poor quality" and 17 out of a possible 93 behavior change techniques were coded, with the majority targeting the intervention function 'education'. CONCLUSIONS: Hearing loss and tinnitus due to recreational noise exposure are major public health concerns yet very few studies have examined preventive interventions. The present systematic review sets the agenda for the future development and testing of evidence-based interventions designed to prevent future hearing loss and tinnitus caused by noise in recreational settings, by recommending systematic approaches to intervention design, and implementation of intervention functions beyond education, such as incentivization, enablement and modeling.


Assuntos
Dispositivos de Proteção das Orelhas , Perda Auditiva Provocada por Ruído/prevenção & controle , Audição , Ruído/efeitos adversos , Recreação , Zumbido/prevenção & controle , Humanos
19.
Int J Audiol ; 59(sup1): S31-S39, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-31714149

RESUMO

Objective: Study the effects of hearing loss and language proficiency in a speech task over radio transmission.Design: Four TCAPS device conditions (2 models × 2 talk-through modes) were investigated with the Modified Rhyme Test (MRT) conducted in talker-listener pairs immersed in 85-dBA noise. Speech quality ratings and preferred radio volume levels were also collected.Study sample: Thirty-six participants divided into three groups (control, non-fluent, hearing-impaired) took part in the experiment. Participants acted as talkers and listeners when paired with a unique standard individual (fluent and normal hearing) of the same gender.Results: MRT scores were significantly lower in many device conditions when the non-fluent group of participants acted as listeners and talkers and when the hearing-impaired participants acted as listeners, compared to the control group. MRT results were also consistently poorer with one device configured for bone-conducted voice pick-up in the occluded ear compared to another one equipped with an external mouth microphone. Talk-through settings had little effect. MRT results were reflected in the subjective quality ratings. Participants with hearing loss used higher radio volume levels.Conclusions: Language proficiency, hearing loss and method of sensing the talker's voice are key issues to consider with TCAPS devices.


Assuntos
Auxiliares de Comunicação para Pessoas com Deficiência , Perda Auditiva/psicologia , Idioma , Rádio , Inteligibilidade da Fala , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Testes de Discriminação da Fala , Percepção da Fala , Voz , Adulto Jovem
20.
Paediatr Child Health ; 25(4): 216-221, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32549736

RESUMO

INTRODUCTION: Previous research has suggested that hand dryers may operate at dangerously loud levels for adults. No research has explored whether they operate at a safe level for children's hearing. Children's ears are more sensitive to damage from loud sounds than adult ears. Health Canada prohibits the sale of toys with peak loudness greater than 100 dB. This study tested installed dryers in public washrooms to see if they were safe for children's hearing. METHODS: Forty-four hand dryers in public washrooms were each measured for peak sound levels in a standardized fashion, including at children's ear canal heights. Each dryer was measured at 10 different combinations of heights and distances from the wall, and with and without hands in the air stream coming from the hand dryer, for a total of 20 measurements per dryer. RESULTS: Xlerator units performed the loudest, with all being louder than 100 dBA at all measurements whenever hands were in the airstream. Several Dyson Airblade models were also very loud, including the single loudest measurement of 121 dBA. While some other units operated at low sound levels, many units were louder at children's ear heights than at adult ear heights. DISCUSSION: Many dryers operated much louder than their manufacturers claimed, usually greater than 100 dBA (the maximum allowable noise level for products/toys meant for children). CONCLUSION: This study suggests that many hand dryers operate at levels far louder than their manufacturers claim and at levels that are clearly dangerous to children's hearing.

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