The appropriate axillary procedure after a positive sentinel node in breast cancer patients: the 'Hôpital Tenon' score revisited. A two-institution study
Clin. transl. oncol. (Print)
; 18(11): 1098-1105, nov. 2016. tab, graf
Article
in En
| IBECS
| ID: ibc-156875
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
Introduction. Until recently, completion ALND has been considered the standard of care after a positive SN in breast cancer patients. However, most patients will not display further axillary involvement. The Tenon score is a simple nomogram that can be used intraoperatively to avoid completion ALND in low-risk patients. We aimed at validating the Tenon score on a SN-positive patient sample that had been preoperatively selected using axillary US examination. Patients and method. We used a retrospective analysis of our bicentric database that included 246 breast cancer patients with a positive SN. We calculated sensitivity, specificity, as well as positive and negative predictive values for each cut-off point. ROCs were constructed and corresponding AUC values were calculated as a measure of discriminative capacity. Results. At least one non-SN was positive in 52 patients (21.1 %). 118 patients (48 %) had a score up to 5. Among them, three had at least one positive non-SN. NPV was 97.5 %. Using that threshold, the ROCs analysis showed an AUC of 0.822 (95 % CI 0.764-0.880). Conclusion. Use of preoperative axillary US examination led to a modification of the proposed Tenon cut-off value from 3.5 to 5 to attain good predictive power for non-SN status. Straightforward intraoperative use of the Tenon score may be considered an advantage over other available nomograms (AU)
RESUMEN
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Collection:
06-national
/
ES
Database:
IBECS
Main subject:
Prognosis
/
Breast Neoplasms
/
Sensitivity and Specificity
/
Sentinel Lymph Node Biopsy
/
Preoperative Period
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
Language:
En
Journal:
Clin. transl. oncol. (Print)
Year:
2016
Type:
Article