Antisense oligodeoxynucleotides against the muscarinic m2, but not m4, receptor supports its role as autoreceptors in the rat hippocampus.

Kitaichi, K; Hori, T; Srivastava, L K; Quirion, R

Kitaichi, K; Hori, T; Srivastava, L K; Quirion, R.

Affiliation

Kitaichi K; Douglas Hospital Research Centre, Department of Psychiatry, Faculty of Medicine, McGill University, Montreal, Quebec, Canada.

Brain Res Mol Brain Res ; 67(1): 98-106, 1999 Apr 06.

Article in En | MEDLINE | ID: mdl-10101237

Subject(s)

Autoreceptors/genetics; Hippocampus/chemistry; Receptors, Muscarinic/genetics; Acetylcholine/analysis; Acetylcholine/metabolism; Animals; Antisense Elements (Genetics); Autoreceptors/metabolism; Brain Chemistry/drug effects; Brain Chemistry/physiology; Choline O-Acetyltransferase/analysis; Choline O-Acetyltransferase/metabolism; Gas Chromatography-Mass Spectrometry; Hippocampus/enzymology; Male; Microdialysis; Muscarinic Antagonists/pharmacology; Parasympatholytics/pharmacology; Pirenzepine/analogs & derivatives; Pirenzepine/pharmacology; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic/metabolism; Tritium

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Muscarinic / Autoreceptors / Hippocampus Limits: Animals Language: En Journal: Brain Res Mol Brain Res Journal subject: BIOLOGIA MOLECULAR / CEREBRO Year: 1999 Type: Article Affiliation country: Canada

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