EVI2B, a gene lying in an intron of the neurofibromatosis type 1 (NF1) gene, is as the NF1 gene involved in differentiation of melanocytes and keratinocytes and is overexpressed in cells derived from NF1 neurofibromas.

Kaufmann, D; Gruener, S; Braun, F; Stark, M; Griesser, J; Hoffmeyer, S; Bartelt, B

Kaufmann, D; Gruener, S; Braun, F; Stark, M; Griesser, J; Hoffmeyer, S; Bartelt, B.

Affiliation

Kaufmann D; Department of Human Genetics, University of Ulm, Germany.

DNA Cell Biol ; 18(5): 345-56, 1999 May.

Article in En | MEDLINE | ID: mdl-10360836

Subject(s)

Gene Expression Regulation, Neoplastic; Genes, Neurofibromatosis 1; Keratinocytes/pathology; Melanocytes/pathology; Neurofibroma/pathology; Adolescent; Adult; Cafe-au-Lait Spots/metabolism; Calcium/pharmacology; Cell Differentiation/drug effects; Cell Differentiation/genetics; Cells, Cultured; Child; Child, Preschool; Fibroblast Growth Factor 2/pharmacology; Fibroblasts/metabolism; Humans; Introns; Keratinocytes/drug effects; Melanocytes/drug effects; Neurofibroma/genetics; RNA, Messenger/metabolism; Skin/metabolism; Skin/pathology; Tetradecanoylphorbol Acetate/pharmacology

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Keratinocytes / Genes, Neurofibromatosis 1 / Melanocytes / Neurofibroma Limits: Adolescent / Adult / Child / Child, preschool / Humans Language: En Journal: DNA Cell Biol Journal subject: BIOLOGIA MOLECULAR Year: 1999 Type: Article Affiliation country: Germany

Search on Google

XML

PubMed Links