In vivo receptor occupancy of NRA0045, a putative atypical antipsychotic, in rats.

Chaki, S; Funakoshi, T; Yoshikawa, R; Okuyama, S; Kumagai, T; Nakazato, A; Nagamine, M; Tomisawa, K

Chaki, S; Funakoshi, T; Yoshikawa, R; Okuyama, S; Kumagai, T; Nakazato, A; Nagamine, M; Tomisawa, K.

Affiliation

Chaki S; 1st Laboratory, Medicinal Research Laboratories, Taisho Pharmaceutical Co., Ltd., Ohmiya, Saitama, Japan. s13555@ccm.taisho.co.jp

Neuropharmacology ; 38(8): 1185-94, 1999 Aug.

Article in En | MEDLINE | ID: mdl-10462131

Subject(s)

Antipsychotic Agents/metabolism; Pyrrolidines/metabolism; Receptors, Adrenergic, alpha-1/metabolism; Receptors, Dopamine/metabolism; Receptors, Serotonin/metabolism; Thiazoles/metabolism; Animals; Antipsychotic Agents/antagonists & inhibitors; Antipsychotic Agents/therapeutic use; Binding, Competitive; Cerebral Cortex/metabolism; Clozapine/pharmacology; Corpus Striatum/metabolism; Dopamine Antagonists/pharmacology; Haloperidol/pharmacology; Male; Nucleus Accumbens/metabolism; Pyrrolidines/antagonists & inhibitors; Pyrrolidines/therapeutic use; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Risperidone/pharmacology; Schizophrenia/drug therapy; Thiazoles/antagonists & inhibitors; Thiazoles/therapeutic use

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Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolidines / Thiazoles / Antipsychotic Agents / Receptors, Serotonin / Receptors, Dopamine / Receptors, Adrenergic, alpha-1 Limits: Animals Language: En Journal: Neuropharmacology Year: 1999 Type: Article Affiliation country: Japan

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