Improvement in solubility and dissolution rate of 1, 2-dithiole-3-thiones upon complexation with beta-cyclodextrin and its hydroxypropyl and sulfobutyl ether-7 derivatives.

Dollo, G; Le Corre, P; Chollet, M; Chevanne, F; Bertault, M; Burgot, J L; Le Verge, R

Dollo, G; Le Corre, P; Chollet, M; Chevanne, F; Bertault, M; Burgot, J L; Le Verge, R.

Affiliation

Dollo G; Laboratoire de Pharmacie Galénique et Biopharmacie and Laboratoire de Chimie Analytique, Faculté des Sciences Pharmaceutiques et Biologiques, Université de Rennes I, 35043 Rennes Cedex, France. Gilles.Dollo@univ-rennes1.fr

J Pharm Sci ; 88(9): 889-95, 1999 Sep.

Article in En | MEDLINE | ID: mdl-10479350

Subject(s)

Cyclodextrins/chemistry; Thiones/chemistry; beta-Cyclodextrins; 2-Hydroxypropyl-beta-cyclodextrin; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Kinetics; Microscopy, Electron, Scanning; Particle Size; Solubility; Spectrophotometry, Ultraviolet

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Collection: 01-internacional Database: MEDLINE Main subject: Thiones / Cyclodextrins / Beta-Cyclodextrins Language: En Journal: J Pharm Sci Year: 1999 Type: Article Affiliation country: France

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