The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis.

Blanchard, H; Kodandapani, L; Mittl, P R; Marco, S D; Krebs, J F; Wu, J C; Tomaselli, K J; Grütter, M G

Blanchard, H; Kodandapani, L; Mittl, P R; Marco, S D; Krebs, J F; Wu, J C; Tomaselli, K J; Grütter, M G.

Affiliation

Blanchard H; Biochemisches Institut Universität Zürich Winterthurer Strasse 190, CH-8057, Zürich, Switzerland.

Structure ; 7(9): 1125-33, 1999 Sep 15.

Article in En | MEDLINE | ID: mdl-10508784

Subject(s)

Apoptosis/physiology; Caspase Inhibitors; Caspases/chemistry; Oligopeptides/chemistry; Protease Inhibitors/chemistry; Amino Acid Sequence; Binding Sites; Caspase 8; Caspase 9; Caspases/metabolism; Crystallography, X-Ray; Dimerization; Models, Molecular; Molecular Sequence Data; Oligopeptides/metabolism; Protease Inhibitors/metabolism; Protein Conformation; Protein Structure, Quaternary; Substrate Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Protease Inhibitors / Apoptosis / Caspases / Caspase Inhibitors Type of study: Prognostic_studies Language: En Journal: Structure Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Year: 1999 Type: Article Affiliation country: Switzerland

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