Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia.

Sun, L; Goodman, P A; Wood, C M; Crotty, M L; Sensel, M; Sather, H; Navara, C; Nachman, J; Steinherz, P G; Gaynon, P S; Seibel, N; Vassilev, A; Juran, B D; Reaman, G H; Uckun, F M

Sun, L; Goodman, P A; Wood, C M; Crotty, M L; Sensel, M; Sather, H; Navara, C; Nachman, J; Steinherz, P G; Gaynon, P S; Seibel, N; Vassilev, A; Juran, B D; Reaman, G H; Uckun, F M.

Affiliation

Sun L; Parker Hughes Cancer Center and Children's Cancer Group ALL Biology Reference Laboratory, Hughes Institute, St Paul, MN 55113, USA.

J Clin Oncol ; 17(12): 3753-66, 1999 Dec.

Article in En | MEDLINE | ID: mdl-10577847

Subject(s)

Alternative Splicing; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics; Transcription Factors/genetics; Adolescent; Adult; Animals; Base Sequence; Child; Child, Preschool; DNA/metabolism; Female; Humans; Ikaros Transcription Factor; Male; Mice; Molecular Sequence Data; Precursor Cell Lymphoblastic Leukemia-Lymphoma/metabolism; Protein Isoforms/biosynthesis; Protein Isoforms/genetics; RNA, Messenger/analysis; RNA, Messenger/metabolism; Sequence Homology, Nucleic Acid; Subcellular Fractions; Transcription Factors/biosynthesis; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Gene Expression Regulation, Neoplastic / Alternative Splicing / DNA-Binding Proteins / Precursor Cell Lymphoblastic Leukemia-Lymphoma Type of study: Prognostic_studies Limits: Adolescent / Adult / Animals / Child / Child, preschool / Female / Humans / Male Language: En Journal: J Clin Oncol Year: 1999 Type: Article Affiliation country: United States

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