Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway.

Lee, R J; Albanese, C; Fu, M; D'Amico, M; Lin, B; Watanabe, G; Haines, G K; Siegel, P M; Hung, M C; Yarden, Y; Horowitz, J M; Muller, W J; Pestell, R G

Lee, R J; Albanese, C; Fu, M; D'Amico, M; Lin, B; Watanabe, G; Haines, G K; Siegel, P M; Hung, M C; Yarden, Y; Horowitz, J M; Muller, W J; Pestell, R G.

Affiliation

Lee RJ; Department of Developmental Biology, The Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

Mol Cell Biol ; 20(2): 672-83, 2000 Jan.

Article in En | MEDLINE | ID: mdl-10611246

Subject(s)

Carrier Proteins; Cell Cycle Proteins; Cell Transformation, Neoplastic/pathology; Cyclin D1/metabolism; MAP Kinase Signaling System; Receptor, ErbB-2/metabolism; Transcription Factors/metabolism; Animals; Binding Sites; Cyclin D1/antagonists & inhibitors; Cyclin D1/genetics; DNA-Binding Proteins/metabolism; E2F Transcription Factors; E2F1 Transcription Factor; Humans; JNK Mitogen-Activated Protein Kinases; Mammary Glands, Animal/metabolism; Mammary Glands, Animal/pathology; Mice; Mice, Nude; Mice, Transgenic; Mitogen-Activated Protein Kinases/antagonists & inhibitors; Mitogen-Activated Protein Kinases/metabolism; Monomeric GTP-Binding Proteins/genetics; Monomeric GTP-Binding Proteins/metabolism; Mutation/genetics; Promoter Regions, Genetic/genetics; Proto-Oncogene Mas; RNA, Antisense/genetics; RNA, Antisense/physiology; Receptor, ErbB-2/antagonists & inhibitors; Receptor, ErbB-2/genetics; Retinoblastoma-Binding Protein 1; Sp1 Transcription Factor/metabolism; Sp3 Transcription Factor; Transcription Factor DP1; Transcriptional Activation; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Carrier Proteins / Cell Transformation, Neoplastic / Receptor, ErbB-2 / Cell Cycle Proteins / Cyclin D1 / MAP Kinase Signaling System Type of study: Prognostic_studies Language: En Journal: Mol Cell Biol Year: 2000 Type: Article Affiliation country: United States

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