CD4(+) T helper cells engineered to produce latent TGF-beta1 reverse allergen-induced airway hyperreactivity and inflammation.

Hansen, G; McIntire, J J; Yeung, V P; Berry, G; Thorbecke, G J; Chen, L; DeKruyff, R H; Umetsu, D T

Hansen, G; McIntire, J J; Yeung, V P; Berry, G; Thorbecke, G J; Chen, L; DeKruyff, R H; Umetsu, D T.

Affiliation

Hansen G; Division of Immunology, Department of Pediatrics, Stanford University, Stanford, California 94305, USA.

J Clin Invest ; 105(1): 61-70, 2000 Jan.

Article in En | MEDLINE | ID: mdl-10619862

Subject(s)

Allergens/immunology; Bronchial Hyperreactivity/therapy; CD4-Positive T-Lymphocytes/physiology; Genetic Therapy; Pneumonia/therapy; Transforming Growth Factor beta/physiology; Animals; Cell Line; Eosinophilia/prevention & control; Interferon-gamma/biosynthesis; Mice; Mice, Inbred BALB C; Mice, SCID; Ovalbumin/immunology

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia / Allergens / Genetic Therapy / CD4-Positive T-Lymphocytes / Transforming Growth Factor beta / Bronchial Hyperreactivity Limits: Animals Language: En Journal: J Clin Invest Year: 2000 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google