Local morphine withdrawal increases c-fos gene, Fos protein, and oxytocin gene expression in hypothalamic magnocellular neurosecretory cells.

Johnstone, L E; Brown, C H; Meeren, H K; Vuijst, C L; Brooks, P J; Leng, G; Russell, J A

Johnstone, L E; Brown, C H; Meeren, H K; Vuijst, C L; Brooks, P J; Leng, G; Russell, J A.

Affiliation

Johnstone LE; Department of Biomedical Sciences, University Medical School, Edinburgh, EH8 9XD, Scotland, United Kingdom.

J Neurosci ; 20(3): 1272-80, 2000 Feb 01.

Article in En | MEDLINE | ID: mdl-10648731

Subject(s)

Gene Expression; Hypothalamus/physiology; Morphine/adverse effects; Narcotics/adverse effects; Oxytocin/genetics; Proto-Oncogene Proteins c-fos/genetics; Proto-Oncogene Proteins c-fos/metabolism; Substance Withdrawal Syndrome/genetics; Adrenergic alpha-Antagonists/pharmacology; Animals; Female; Hypothalamus/cytology; Hypothalamus/metabolism; Naloxone/pharmacology; Narcotic Antagonists/administration & dosage; Narcotic Antagonists/pharmacology; Neurosecretory Systems/cytology; Neurosecretory Systems/physiology; Paraventricular Hypothalamic Nucleus/metabolism; RNA, Heterogeneous Nuclear/metabolism; RNA, Messenger/metabolism; Rats; Supraoptic Nucleus/metabolism

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Substance Withdrawal Syndrome / Oxytocin / Gene Expression / Proto-Oncogene Proteins c-fos / Hypothalamus / Morphine / Narcotics Limits: Animals Language: En Journal: J Neurosci Year: 2000 Type: Article Affiliation country: United kingdom

Fulltext

XML

PubMed Links

Search on Google