Placental transfer and pharmacokinetics of a single dermal dose of [14C]methyl parathion in rats.

Abu-Qare, A W; Abdel-Rahman, A A; Kishk, A M; Abou-Donia, M B

Abu-Qare, A W; Abdel-Rahman, A A; Kishk, A M; Abou-Donia, M B.

Affiliation

Abu-Qare AW; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

Toxicol Sci ; 53(1): 5-12, 2000 Jan.

Article in En | MEDLINE | ID: mdl-10653515

Subject(s)

Insecticides/pharmacokinetics; Maternal-Fetal Exchange/physiology; Methyl Parathion/pharmacokinetics; Placenta/metabolism; Administration, Cutaneous; Animals; Animals, Newborn; Area Under Curve; Chromatography, High Pressure Liquid; Female; Fetus/metabolism; Half-Life; Nitrophenols/metabolism; Paraoxon/analogs & derivatives; Paraoxon/metabolism; Pregnancy; Rats; Rats, Sprague-Dawley; Tissue Distribution

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Collection: 01-internacional Database: MEDLINE Main subject: Placenta / Insecticides / Maternal-Fetal Exchange / Methyl Parathion Type of study: Prognostic_studies Limits: Animals / Pregnancy Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2000 Type: Article Affiliation country: United States

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