Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation.

Brdicka, T; Pavlistová, D; Leo, A; Bruyns, E; Korínek, V; Angelisová, P; Scherer, J; Shevchenko, A; Hilgert, I; Cerný, J; Drbal, K; Kuramitsu, Y; Kornacker, B; Horejsí, V; Schraven, B

Brdicka, T; Pavlistová, D; Leo, A; Bruyns, E; Korínek, V; Angelisová, P; Scherer, J; Shevchenko, A; Hilgert, I; Cerný, J; Drbal, K; Kuramitsu, Y; Kornacker, B; Horejsí, V; Schraven, B.

Affiliation

Brdicka T; Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, 14220 Prague, Czech Republic.

J Exp Med ; 191(9): 1591-604, 2000 May 01.

Article in En | MEDLINE | ID: mdl-10790433

Subject(s)

Glycosphingolipids/metabolism; Lymphocyte Activation; Membrane Proteins/metabolism; Phosphoproteins/metabolism; Protein-Tyrosine Kinases/metabolism; T-Lymphocytes/immunology; Adaptor Proteins, Signal Transducing; Amino Acid Sequence; CD3 Complex/metabolism; CSK Tyrosine-Protein Kinase; Cloning, Molecular; DNA, Complementary/genetics; Humans; Membrane Proteins/genetics; Molecular Sequence Data; Phosphoproteins/genetics; Protein Binding; Receptors, Antigen, T-Cell/metabolism; Signal Transduction; src-Family Kinases

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphoproteins / Protein-Tyrosine Kinases / Glycosphingolipids / Lymphocyte Activation / T-Lymphocytes / Membrane Proteins Type of study: Risk_factors_studies Limits: Humans Language: En Journal: J Exp Med Year: 2000 Type: Article Affiliation country: Czech Republic

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