Osteoporosis: an unusual presentation of childhood Crohn's disease.
J Clin Endocrinol Metab
; 85(6): 2122-6, 2000 Jun.
Article
in En
| MEDLINE
| ID: mdl-10852438
ABSTRACT
Osteoporosis is known to be associated with Crohn's disease. We report a 12-yr-old boy without a history of steroid use, in whom severe osteoporosis and multiple collapsed vertebrae were the presenting manifestations of Crohn's disease. After treatment of the Crohn's disease, he resumed normal growth and progressed through puberty. Concomitantly, he demonstrated a substantial recovery of vertebral bone mineral density and structure. Possible pathophysiological mechanisms underlying the osteoporosis and the subsequent improvement in bone density are discussed.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Osteoporosis
/
Methylprednisolone
/
Crohn Disease
/
Diphosphonates
Type of study:
Diagnostic_studies
Limits:
Child
/
Humans
/
Male
Language:
En
Journal:
J Clin Endocrinol Metab
Year:
2000
Type:
Article
Affiliation country:
United States