Analysis of specific gene mutations in the transforming growth factor-beta signal transduction pathway in human ovarian cancer.

Wang, D; Kanuma, T; Mizunuma, H; Takama, F; Ibuki, Y; Wake, N; Mogi, A; Shitara, Y; Takenoshita, S

Wang, D; Kanuma, T; Mizunuma, H; Takama, F; Ibuki, Y; Wake, N; Mogi, A; Shitara, Y; Takenoshita, S.

Affiliation

Wang D; Department of Obstetrics and Gynecology, Gunma University School of Medicine, Japan.

Cancer Res ; 60(16): 4507-12, 2000 Aug 15.

Article in En | MEDLINE | ID: mdl-10969799

Subject(s)

Activin Receptors, Type I; Frameshift Mutation/genetics; Loss of Heterozygosity/genetics; Ovarian Neoplasms/genetics; Signal Transduction/genetics; Transforming Growth Factor beta/genetics; Adolescent; Adult; Aged; Aged, 80 and over; Blotting, Western; DNA Mutational Analysis; DNA-Binding Proteins/genetics; Female; Humans; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Protein Serine-Threonine Kinases/genetics; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta/genetics; Signal Transduction/physiology; Smad2 Protein; Smad4 Protein; Trans-Activators/genetics; Transforming Growth Factor beta/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Signal Transduction / Frameshift Mutation / Transforming Growth Factor beta / Loss of Heterozygosity / Activin Receptors, Type I Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Middle aged Language: En Journal: Cancer Res Year: 2000 Type: Article Affiliation country: Japan

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