Excessive activation of serotonin (5-HT) 1B receptors disrupts the formation of sensory maps in monoamine oxidase a and 5-ht transporter knock-out mice.

Salichon, N; Gaspar, P; Upton, A L; Picaud, S; Hanoun, N; Hamon, M; De Maeyer , E; Murphy, D L; Mossner, R; Lesch, K P; Hen, R; Seif, I

Salichon, N; Gaspar, P; Upton, A L; Picaud, S; Hanoun, N; Hamon, M; De Maeyer , E; Murphy, D L; Mossner, R; Lesch, K P; Hen, R; Seif, I.

Affiliation

Salichon N; Centre National de la Recherche Scientifique, Unité Mixte de Recherche 146, Institut Curie, 91405 Orsay, France.

J Neurosci ; 21(3): 884-96, 2001 Feb 01.

Article in En | MEDLINE | ID: mdl-11157075

Subject(s)

Membrane Glycoproteins/deficiency; Membrane Transport Proteins; Monoamine Oxidase/deficiency; Movement Disorders/genetics; Nerve Tissue Proteins; Receptors, Serotonin/deficiency; Receptors, Serotonin/metabolism; Animals; Brain Mapping; Carrier Proteins/genetics; Crosses, Genetic; Female; Geniculate Bodies/cytology; Geniculate Bodies/metabolism; Immunohistochemistry; Male; Membrane Glycoproteins/genetics; Mice; Mice, Inbred Strains; Mice, Knockout; Monoamine Oxidase/genetics; Motor Activity/genetics; Movement Disorders/physiopathology; Neurons/metabolism; Neurons/pathology; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin/genetics; Retina/cytology; Retina/metabolism; Serotonin/metabolism; Serotonin/pharmacology; Serotonin Plasma Membrane Transport Proteins; Somatosensory Cortex/metabolism; Somatosensory Cortex/pathology; Somatosensory Cortex/physiopathology; Thalamus/cytology; Thalamus/metabolism; Tryptophan Hydroxylase/antagonists & inhibitors; Visual Pathways/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Transport Proteins / Membrane Glycoproteins / Receptors, Serotonin / Monoamine Oxidase / Movement Disorders / Nerve Tissue Proteins Language: En Journal: J Neurosci Year: 2001 Type: Article Affiliation country: France

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