Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax.

Versées, W; Decanniere, K; Pellé, R; Depoorter, J; Brosens, E; Parkin, D W; Steyaert, J

Versées, W; Decanniere, K; Pellé, R; Depoorter, J; Brosens, E; Parkin, D W; Steyaert, J.

Affiliation

Versées W; Dienst Ultrastructuur, Vlaams Interuniversitair instituut voor Biotechnologie, Vrije Universiteit Brussel, Paardenstraat 65, Sint-Genesius-Rode, B-1640, Belgium.

J Mol Biol ; 307(5): 1363-79, 2001 Apr 13.

Article in En | MEDLINE | ID: mdl-11292348

Subject(s)

N-Glycosyl Hydrolases/chemistry; N-Glycosyl Hydrolases/metabolism; Trypanosoma vivax/enzymology; Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; Crithidia fasciculata/enzymology; Crystallography, X-Ray; Dimerization; Drug Design; Histidine/genetics; Histidine/metabolism; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Weight; N-Glycosyl Hydrolases/antagonists & inhibitors; N-Glycosyl Hydrolases/genetics; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Subunits; Recombinant Fusion Proteins/antagonists & inhibitors; Recombinant Fusion Proteins/chemistry; Recombinant Fusion Proteins/metabolism; Sequence Alignment; Structure-Activity Relationship; Substrate Specificity; Trypanosoma vivax/genetics; Tubercidin/metabolism; Water/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Trypanosoma vivax / N-Glycosyl Hydrolases Limits: Animals Language: En Journal: J Mol Biol Year: 2001 Type: Article Affiliation country: Belgium

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