Endothelial progenitor cells for regeneration.
Hum Cell
; 13(4): 153-60, 2000 Dec.
Article
in En
| MEDLINE
| ID: mdl-11329932
ABSTRACT
Endothelial progenitor cells (EPCs) have been recently isolated from peripheral blood and bone marrow (BM), and shown to be incorporated into sites of physiological and pathological neovascularization in vivo. In contrast to differentiated endothelial cells (ECs), transplantation of EPCs successfully enhanced vascular development by in situ differentiation and proliferation within ischemic organs. Based on such a novel concept of closed up function on EPCs in postnatal neovascularization, the beneficial property of EPC is attractive for cell therapy as well as cell-mediated gene therapy applications targeting regeneration of ischemic tissue.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Regeneration
/
Endothelium, Vascular
Limits:
Humans
Language:
En
Journal:
Hum Cell
Year:
2000
Type:
Article
Affiliation country:
United States