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An improved helper-dependent adenoviral vector allows persistent gene expression after intramuscular delivery and overcomes preexisting immunity to adenovirus.
Maione, D; Della Rocca, C; Giannetti, P; D'Arrigo, R; Liberatoscioli, L; Franlin, L L; Sandig, V; Ciliberto, G; La Monica, N; Savino, R.
Affiliation
  • Maione D; Istituto di Ricerche di Biologia Molecolare P. Angeletti, 00040 Pomezia, Rome, Italy.
Proc Natl Acad Sci U S A ; 98(11): 5986-91, 2001 May 22.
Article in En | MEDLINE | ID: mdl-11353820

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenoviruses, Human / Genetic Vectors / Helper Viruses Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2001 Type: Article Affiliation country: Italy

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenoviruses, Human / Genetic Vectors / Helper Viruses Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2001 Type: Article Affiliation country: Italy