C2-ceramide signaling in glioma cells: synergistic enhancement of CD95-mediated, caspase-dependent apoptosis.

Wagenknecht, B; Roth, W; Gulbins, E; Wolburg, H; Weller, M

Wagenknecht, B; Roth, W; Gulbins, E; Wolburg, H; Weller, M.

Affiliation

Wagenknecht B; Laboratory of Molecular Neuro-Oncology, Department of Neurology, University of Tübingen, Tübingen, Germany.

Cell Death Differ ; 8(6): 595-602, 2001 Jun.

Article in En | MEDLINE | ID: mdl-11536010

Subject(s)

Apoptosis/drug effects; Caspases/metabolism; Neuroglia/drug effects; Signal Transduction/drug effects; Sphingosine/pharmacology; fas Receptor/metabolism; Amino Acid Chloromethyl Ketones/pharmacology; Caspase Inhibitors; Cytochrome c Group/metabolism; Drug Synergism; Enzyme Activation/drug effects; Fas Ligand Protein; Humans; Immunoblotting; Membrane Glycoproteins/metabolism; Microscopy, Electron; Mitochondria/drug effects; Mitochondria/metabolism; Neuroglia/pathology; Neuroglia/ultrastructure; Poly(ADP-ribose) Polymerases/metabolism; Sphingosine/analogs & derivatives; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Sphingosine / Signal Transduction / Neuroglia / Apoptosis / Fas Receptor / Caspases Limits: Humans Language: En Journal: Cell Death Differ Year: 2001 Type: Article Affiliation country: Germany

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