Direct relation between BCR-ABL tyrosine kinase activity and cyclin D2 expression in lymphoblasts.

Deininger, M W; Vieira, S A; Parada, Y; Banerji, L; Lam, E W; Peters, G; Mahon, F X; Köhler, T; Goldman, J M; Melo, J V

Deininger, M W; Vieira, S A; Parada, Y; Banerji, L; Lam, E W; Peters, G; Mahon, F X; Köhler, T; Goldman, J M; Melo, J V.

Affiliation

Deininger MW; Department of Haematology, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London W12 0NN, United Kingdom.

Cancer Res ; 61(21): 8005-13, 2001 Nov 01.

Article in En | MEDLINE | ID: mdl-11691826

Subject(s)

Cyclins/biosynthesis; Fusion Proteins, bcr-abl/metabolism; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/metabolism; Lymphocytes/metabolism; Precursor Cell Lymphoblastic Leukemia-Lymphoma/metabolism; Protein-Tyrosine Kinases/metabolism; Benzamides; Blast Crisis; Cyclin D2; Cyclins/genetics; Down-Regulation; Fusion Proteins, bcr-abl/antagonists & inhibitors; Fusion Proteins, bcr-abl/genetics; G1 Phase/drug effects; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/enzymology; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics; Lymphocytes/enzymology; Phosphatidylinositol 3-Kinases/physiology; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma/enzymology; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics; Protein-Tyrosine Kinases/antagonists & inhibitors; Protein-Tyrosine Kinases/genetics; Pyrimidines/pharmacology; S Phase/drug effects; Signal Transduction; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Protein-Tyrosine Kinases / Lymphocytes / Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Fusion Proteins, bcr-abl / Cyclins / Precursor Cell Lymphoblastic Leukemia-Lymphoma Limits: Humans Language: En Journal: Cancer Res Year: 2001 Type: Article Affiliation country: United kingdom

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