Activation of microsomal epoxide hydrolase by interaction with cytochromes P450: kinetic analysis of the association and substrate-specific activation of epoxide hydrolase function.

Taura Ki, Ken-ichiro; Yamada, Hideyuki; Naito, Eri; Ariyoshi, Noritaka; Mori Ma, Masa-aki; Oguri, Kazuta

Taura Ki, Ken-ichiro; Yamada, Hideyuki; Naito, Eri; Ariyoshi, Noritaka; Mori Ma, Masa-aki; Oguri, Kazuta.

Affiliation

Taura Ki K; Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higash-ku Fukuoka 812-8582, Japan.

Arch Biochem Biophys ; 402(2): 275-80, 2002 Jun 15.

Article in En | MEDLINE | ID: mdl-12051674

Subject(s)

Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System/chemistry; Epoxide Hydrolases/chemistry; Steroid 16-alpha-Hydroxylase; Animals; Benzopyrenes/chemistry; Cytochrome P-450 CYP1A1/chemistry; Cytochrome P-450 CYP2B1/chemistry; Cytochrome P450 Family 2; Epoxy Compounds/chemistry; Kinetics; Rats; Steroid Hydroxylases/chemistry; Substrate Specificity; Surface Plasmon Resonance

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Collection: 01-internacional Database: MEDLINE Main subject: Aryl Hydrocarbon Hydroxylases / Cytochrome P-450 Enzyme System / Steroid 16-alpha-Hydroxylase / Epoxide Hydrolases Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Arch Biochem Biophys Year: 2002 Type: Article Affiliation country: Japan

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