Deracemization of alpha-methylbenzylamine using an enzyme obtained by in vitro evolution.

Alexeeva, Marina; Enright, Alexis; Dawson, Michael J; Mahmoudian, Mahmoud; Turner, Nicholas J

Alexeeva, Marina; Enright, Alexis; Dawson, Michael J; Mahmoudian, Mahmoud; Turner, Nicholas J.

Affiliation

Alexeeva M; Department of Chemistry, Centre for Protein Technology, The University of Edinburgh, King's Buildings, West Mains Road, Edinburgh EH9 3JJ, UK.

Angew Chem Int Ed Engl ; 41(17): 3177-80, 2002 Sep 02.

Article in En | MEDLINE | ID: mdl-12207381

Subject(s)

Amine Oxidase (Copper-Containing)/chemistry; Directed Molecular Evolution/methods; Phenethylamines/chemistry; Amine Oxidase (Copper-Containing)/chemical synthesis; Aspergillus niger/enzymology; Chromatography, High Pressure Liquid; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Escherichia coli/genetics; Escherichia coli/metabolism; Mutagenesis, Site-Directed; Oxidation-Reduction; Peptide Library; Stereoisomerism

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Collection: 01-internacional Database: MEDLINE Main subject: Phenethylamines / Amine Oxidase (Copper-Containing) / Directed Molecular Evolution Language: En Journal: Angew Chem Int Ed Engl Year: 2002 Type: Article Affiliation country: United kingdom

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